Results 51 to 60 of about 9,814 (162)
Small Science, Volume 6, Issue 1, January 2026.Herein, a liver‐targeted nanohybrid formulation, SGLC/DOX@AG, is developed to enhance doxorubicin delivery and reduce vascular toxicity in hepatocellular carcinoma (HCC) treatment. Incorporating an albumin–glucosamine lipid complex, the system shows potent anticancer effects and minimized side effects across in vitro, in vivo, and cancer‐on‐a‐chip ...
Hyelim Kim +11 more
wiley +1 more source
Glycyrrhetinic Acid Induced Apoptosis in Murine Splenocytes.
Biological and Pharmaceutical Bulletin, 2001 Glycyrrhetinic acid (GA) is known to inhibit glucocorticoid metabolism inhibiting 11beta-hydroxysteroid dehydrogenase (11beta-HSD). Moreover, GA administration to mice has been shown to affect the lymphoid organs through elevation of endogenous corticosterone concentration.
H, Horigome, M, Homma, T, Hirano, K, Oka
openaire +3 more sources
Neurogastroenterology &Motility, Volume 38, Issue 1, January 2026.The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi +6 more
wiley +1 more source
Comparative Cytotoxicity of Glycyrrhiza glabra Roots from Different Geographical Origins Against Immortal Human Keratinocyte (HaCaT), Lung Adenocarcinoma (A549) and Liver Carcinoma (HepG2) Cells [PDF]
, 2015 Glycyrrhiza glabra L. (Fabaceae), commonly known as 'liquorice', is a well-known medicinal plant. Roots of this plant have long been used as a sweetening and flavouring agent in food and pharmaceutical products, and also as a traditional remedy for cough,
Akamatsu +26 more
core +1 more source
Analisis Penghambatan Aktivitas Mortalin dengan Senyawa Herbal Indonesia untuk Skrening Anti Kanker melalui In Silico [PDF]
, 2015 The prevalence of cancer in Indonesia is still very high, especially breast and cervical cancer. However, the potent and safe drugs for cancer therapy are still not available.
UB, W. (Widodo)
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Nitric Oxide Is Involved in Heavy Ion-Induced Non-Targeted Effects in Human Fibroblasts [PDF]
, 2019 Previously, we investigated the dose response for chromosomal aberration (CA) for exposures corresponding to less than one particle traversal per cell nucleus by high energy and charge (HZE) particles, and showed that the dose responses for simple ...
Cucinotta, Francis A. +2 more
core +2 more sources
, 2011 The effect of drug on a person may be different than expected because that drug interacts with another drug the person is taking (drug-drug interaction), food, beverages, dietary supplements the person is consuming (drug-nutrient/food interaction) or ...
Arshad Yar Khan +2 more
core +1 more source
Journal of Pharmacy and Pharmacology, 1993 AbstractThe anti-inflammatory profile of dihemiphthalate compounds of glycyrrhetinic acid derivatives in acute rat paw oedema induced by various vasoactive agents was compared with the parent compound. Three dihemiphthalate compounds (the di-sodium salt of 18 β-olean-12-ene-3β,30-diol di-O-hemiphthalate, 18β-olean-9(11),12-dione-3β,30-diol di-O ...
H, Inoue +4 more
openaire +2 more sources
Gap Junctions Are Essential for Generating the Correlated Spike Activity of Neighboring Retinal Ganglion Cells [PDF]
, 2013 Neurons throughout the brain show spike activity that is temporally correlated to that expressed by their neighbors, yet the generating mechanism(s) remains unclear.
Bloomfield, Stewart A. +5 more
core +2 more sources
Renal handling of prednisolone/prednisone: effect of steroid dose and llβ-hydroxysteroid dehydrogenase [PDF]
, 2017 The purposes of this study were: (1) to determine under steady-state conditions whether the renal clearance of prednisolone is concentration dependent, and (2) to establish whether the urinary excretion of prednisolone and its biologically inactive 11 ...
Conti, M. +4 more
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