Results 51 to 60 of about 2,522,082 (192)

Development of a UPLC-TQ/MS Approach for the Determination of Eleven Bioactive Components in Haizao Yuhu Decoction Plus-Minus Haizao and Gancao Drug Combination after Oral Administration in a Rat Model of Hypothyroidism

Molecules, 2016
Haizao Yuhu Decoction (HYD) has been used for approximately 500 years and is well-known in Traditional Chinese Medicine for its efficacy in the treatment of thyroid-related diseases.
Yingchang Ma, Yang Zhang, Yuanjuan Zhai, Zhenhua Zhu, Ying Pan, Dawei Qian, Shulan Su, Xinsheng Fan, Jinao Duan   +8 more
doaj   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Separation of Glycyrrhizic Acid and Its Derivants from Hydrolyzation in Subcritical Water by Macroporous Resin

Molecules, 2020
Glycyrrhizic acid (GL) and its derivants, glycyrrhetinic acid 3-O-mono-β-d-glucuronide (GAMG) and glycyrrhetinic acid (GA) hydrolyzed in subcritical water, are bioactive substances and edulcorators.
Rui Fan
doaj   +1 more source

Practical recommendations for seborrheic dermatitis management: An expert consensus

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 9, Page 1460-1468, September 2026.
This modified Delphi study established expert consensus on Seborrheic Dermatitis management. Key findings prioritize combined topical antifungal and anti‐inflammatory therapy for both acute flares and long‐term maintenance. The consensus also provides a clear framework for escalating to systemic treatment in extensive or refractory cases.
L. Naldi, A. Kyrgidis, G. S. Tiplica, M. A. de Rie, D. Tatsis, P. Gisondi, D. Ioannides, O. Chosidow, M. Deleuran, the Delphi SD study experts   +9 more
wiley   +1 more source

Effect of solid fermentation of Lactobacillus plantarum on the contents of effective components in compound Chinese medicine [PDF]

Zhongguo niangzao
Compound Chinese medicine (Astragalus, licorice and Leonurus japonicus, etc.) were prepared with solid state fermentation by Lactobacillus plantarum BLCC2-0015, BLCC2-0126 and BLCC2-0410.
HOU Nannan, XIE Quanxi, WANG Junxian, WANG Qian, WANG Mei, GU Wei
doaj   +1 more source

Natural Agents for Preventing Skin Damage Induced by Visible Light: A Systematic Review of Preclinical and Clinical Evidence

Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 5, September 2026.
ABSTRACT Background/Purpose Visible light (VL), and particularly high‐energy visible light (HEVL), reaching Earth's surface has emerged as a relevant contributor to skin damage. VL has been implicated in oxidative stress, inflammation, pigmentation disorders, and photoaging, especially in individuals with darker skin phototypes.
Azahara Rodríguez‐Luna, Alicia Zamarrón, Cristina García‐Muñoz, Juan‐Carlos Hernández‐Rodríguez, Henry W. Lim, Salvador González   +5 more
wiley   +1 more source

Comparison of alpha and beta isoforms of glycyrrhetinic acid and carbenoxolone as inhibitors of EDHF-type relaxation

, 2001
The vascular actions of the lipophilic gap junction inhibitors 18alpha-glycyrrhetinic acid, 18beta-glycyrrhetinic acid and the water-soluble hemisuccinate derivative of 18beta-glycyrrhetinic acid, carbenoxolone, were investigated in constricted rings of ...
Chaytor, A.T., Griffith, Tudor Morley, Marsh, W. L., Hutcheson, Iain Richard   +3 more
core   +5 more sources

Transformations in glycyrrhetinic acid: rearrangement of ring A

Journal of Pharmacy and Pharmacology, 1966
Abstract Methyl 11-oxo-18 β-A-neo-oleana-3, 12-dien-30-oate and the corresponding 18α-isomer have been prepared and tested for anti-inflammatory and antidiuretic activity. Relative to methyl glycyrrhetinate, both kinds of activity and toxicity are reduced by the rearrangement.
V, Askam, C M, Baines, H J, Smith
openaire   +2 more sources

Kinetic Compatibility as a Predictor of PTP1B Inhibitor Combination Outcomes: An Integrated Experimental and Computational Study

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Combining PTP1B inhibitors of distinct kinetic mechanisms determines their pharmacological outcome. Integrating enzyme kinetics, docking, molecular dynamics, and membrane‐permeability simulations, we show that mechanistically compatible pairs (competitive + competitive; uncompetitive + mixed) yield additivity, whereas competitive + uncompetitive ...
Jonathan Trapala, Laura I. Álvarez‐Añorve, Nathaly Vasquez‐Martínez, Erika Chavira‐Suárez, Luz Vásquez‐Bochm, Deyamira Matuz‐Mares, Francisco Cortés‐Benítez, Martin González‐Andrade   +7 more
wiley   +1 more source

Biocomputational Prediction of Anticancer Activity of Ayurvedic Plants Inhibiting Cyclin D1: Molecular Docking Study of the Major Active Compounds of Licorice Root Extract (Glycyrrhiza glabra) in Inhibiting Oral Squamous Cell Carcinoma Proliferation

Indonesian Journal of Cancer
Background: Oral squamous cell carcinoma (OSCC) reported for > 90% of oral cancer cases, causing 377,713 new cases and 177,757 deaths in 2020. Treatments like surgery, chemotherapy, and radiotherapy affect patients’ lives. This study focuses on Licorice (
Mohammad Iqbal
doaj   +1 more source