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Pharmacological underlying mechanisms of the anticancer effect of licorice: Bioinformatics and experimental verification

Journal of Holistic Integrative Pharmacy
Purpose: Cancer is the second leading cause of human mortality and has rapidly become a major global issue. According to traditional Chinese medicine (TCM) theory, the primary pathogenesis of cancer is the deficiency of ''vital Qi''.
Mengqi Liu +5 more
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Discovery of a novel broad-spectrum inhibitor against influenza virus A

Virology Journal
The pandemic of influenza A virus (IAV) is on the rise worldwide, however, drug resistance to anti-influenza drugs has been widely found. The viral mutation of IAV highlights the necessitate for discovery of new antiviral agents with broad-spectrum ...
Ran Yu, Peng Li, Rong Shen, Wenting Fei
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The Behavior of Glycyrrhizic Acid and Glycyrrhetinic Acid

Journal of the agricultural chemical society of Japan, 1973
グリシルリチン酸およびグリシルレチン酸を添加した紙巻たばこを人工喫煙して得られるタール中のグリシルレチン酸の定量法を確立した.この方法によって二つの酸の喫煙時における挙動を調べたところ,グリシルリチン酸は喫煙の際,加熱分解して一部グリシルレチン酸となり,グリシルレチン酸は,そのままの形で煙中に移行することが認められた.しかし,煙中へのグリシルレチン酸の移行率は,両者とも非常に少なかった. 従って,たばこ香料として添加された甘草エキス中のグリシルリチン酸は,大部分熱分解されて煙中に移行するものと考えられる.
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Exfoliating effect of β-glycyrrhetinic acid on plaque inducing gingivitis: Comparison with cetylpyridinium chloride. [PDF]