Results 41 to 50 of about 6,278 (169)

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Dynamic Changes and Correlation Analysis of Polysaccharide Content and Color Parameters in Glycyrrhiza Stems and Leaves during Fermentation

Fermentation, 2023
Fermentation can increase the concentration of active ingredients and improve the effectiveness of Chinese herbal medicine. The purpose of this study was to investigate the effect of solid-state fermentation (SSF) on the polysaccharide content and color ...
Juan Du, Yifeng Song, Xia Li, Na Liu, Xiaoping An, Jingwei Qi   +5 more
doaj   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan, Reyhaneh Farghadani, Ammu K. Radhakrishnan   +2 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Cloning and molecular evolution of 9-cis-epoxycarotenoid dioxygenase gene (NCED3) in six species of Glycyrrhiza L

Journal of Traditional Chinese Medical Sciences, 2017
Objective: To understand the evolutionary relationship of NCED3 in Glycyrrhiza L. and find genetic evidence of its local adaptation. Meanwhile, lay the foundation for relieving the demand and subsequent starvation of Glycyrrhiza resources. Methods: NCED3
Li Wang, Guangxi Ren, Mingyang Chen, Jing Chen, Chunsheng Liu   +4 more
doaj   +1 more source

Metabolic Plasticity and Terpenoid Modulation in Zanthoxylum armatum Callus Cultures: Chemical Composition and Biotechnological Perspectives

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 884-899, July 2026.
Graphical abstract illustrating the metabolic dynamics and regulation of terpenoid production in Zanthoxylum armatum callus cultures. On the left, callus initiation and growth from explants are shown, followed by the establishment of suspension cultures.
Sumit Purohit, Balwant Rawat, Ravendra Kumar, Mrinalini Agarwal, Somya Sinha, Shivani Negi, Namini Joshi, Akshita Raj, Prabhakar Semwal, A. Dheerani, Janhvi Mishra Rawat, Mozaniel Santana de Oliveira   +11 more
wiley   +1 more source

Multi‐Induction Strategies in Crops: Mechanisms, Synergistic Effects, and Sustainable Applications for Enhanced Secondary Metabolite Production

Food Frontiers, Volume 7, Issue 4, July 2026.
This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun, Daoyan Xiao, Xingyue Li, Zhaofei Wang, Maoqin Xia, Chao Song, Hong‐Lei Li   +6 more
wiley   +1 more source

Comparative analysis of chloroplast genomes and transcriptomics reveals the adaptation of Glycyrrhiza to salt stress

Plant Signaling & Behavior
Glycyrrhiza is a perennial leguminous plant with salt tolerance, and its roots and rhizomes possess extremely significant medicinal value. The proper salinity can facilitate the growth of Glycyrrhiza and increase its content of medicinal ingredients ...
Mingxiang Huang, Tianxiang Zhang, Yuansheng Duan, Guifeng Zhang, Wei Hong, Yongjun Shu   +5 more
doaj   +1 more source

Tripartite Symbiosis Between Legumes, Arbuscular Mycorrhizal Fungi and Nitrogen Fixing Rhizobia: Interactions and Regulation

Plant, Cell &Environment, Volume 49, Issue 7, Page 3789-3807, July 2026.
ABSTRACT Legume plants can interact with nitrogen‐fixing rhizobia bacteria and arbuscular mycorrhizal fungi (AMF) simultaneously, forming a tripartite symbiotic association. Co‐inoculation studies performed on a variety of legumes have shown that rhizobia and AMF influence each other when they co‐occur in tripartite association and affect host plant ...
Polyxeni Gorgia, Daniela Tsikou
wiley   +1 more source

Polyphenolic compounds in Glycyrrhiza spp.: a potential weapon against multidrug-resistant pathogens

Frontiers in Pharmacology
Antimicrobial resistance (AMR) is a rapidly escalating global health crisis, projected to cause 10 million deaths annually by 2050 without effective intervention.
Muhammad Rafiq, Muhammad Rafiq, Zhaoqi Xie, Zhaoqi Xie, Shahida Hameed, Haijing Xiao, Haijing Xiao, Yiqing Luo, Yiqing Luo, Kai Chen, Kai Chen, Jiaxin Yang, Jiaxin Yang, Lei Hu, Lei Hu, Min Guo, Min Guo, Chunsong Cheng, Chunsong Cheng   +18 more
doaj   +1 more source