Results 71 to 80 of about 4,216 (200)

Ononin, a Natural Isoflavone Glycoside, Alleviates Postoperative Cognitive Dysfunction in Aged Mice by Regulating Neuroinflammation and Oxidative Stress

Brain and Behavior, Volume 15, Issue 10, October 2025.
Ononin alleviates postoperative cognitive dysfunction in aged mice by regulating neuroinflammation and oxidative stress. ABSTRACT Objective Postoperative cognitive dysfunction (POCD) is a serious neurological complication that currently lacks effective clinical prevention and treatment.
Ming Li, Qingmei Peng, Min Zhu, Qilin Liu, Simin Yang, Cansheng Gong, Jingyan Lin, Qingbo Yu   +7 more
wiley   +1 more source

Advances in Atopic Dermatitis Treatment: From Pathogenesis to Natural Product‐Based Therapies

Phytotherapy Research, Volume 39, Issue 10, Page 4444-4473, October 2025.
NPs improve atopic dermatitis mainly include flavonoids, phenols, glycosides, alkaloids, and others. ABSTRACT Atopic dermatitis (AD), a widespread and chronic inflammatory skin disorder, profoundly affects patients' quality of life, imposes significant psychological strain, and adds to the public health burden.
Xinyun Fan, Zibo Liu, Wenjing Yang, Hongying Zhang, Hao Zhong, Yan Pang, Xun Ye, Chunjie Wu, Liang Li   +8 more
wiley   +1 more source

Exogenous ethanol treatment promotes glycyrrhizin accumulation in aseptically grown Glycyrrhiza uralensis seedlings

Plant Signaling & Behavior
Licorice, the dried roots and rhizomes of Glycyrrhiza uralensis Fisch., is one of the most popular herbal medicines used globally. Glycyrrhizin is the primary bioactive component of licorice, exhibiting various pharmacological activities. Herein, we grew
Yuto Nishidono, Ken Tanaka
doaj   +1 more source

Glycyrrhiza uralensis polysaccharides ameliorates cecal ligation and puncture-induced sepsis by inhibiting the cGAS-STING signaling pathway

Frontiers in Pharmacology
Ethnopharmacological relevance:G. uralensis Fisch. (Glycyrrhiza uralensis) is an ancient and widely used traditional Chinese medicine with good efficacy in clearing heat and detoxifying action.
Siwen Hui, Siwen Hui, Siwen Hui, Wen Kan, Wen Kan, Shuanglin Qin, Shuanglin Qin, Shuanglin Qin, Ping He, Ping He, Jia Zhao, Jia Zhao, Hui Li, Hui Li, Jun Bai, Jincai Wen, Jincai Wen, Wenqing Mou, Wenqing Mou, Manting Hou, Manting Hou, Ziying Wei, Ziying Wei, Li Lin, Li Lin, Xiaohe Xiao, Xiaohe Xiao, Guang Xu, Guang Xu, Guang Xu, Zhaofang Bai, Zhaofang Bai   +31 more
doaj   +1 more source

Metagenomics insights into responses of rhizobacteria and their alleviation role in licorice allelopathy

Microbiome, 2023
Background Allelopathy is closely associated with rhizosphere biological processes, and rhizosphere microbial communities are essential for plant development.
Yang Liu, Hao Wang, Xun Qian, Jie Gu, Weimin Chen, Xihui Shen, Shiheng Tao, Shuo Jiao, Gehong Wei   +8 more
doaj   +1 more source

The synergic effect of glycyrrhizic acid and low frequency electromagnetic field on angiogenesis in chick chorioallantoic membrane [PDF]

, 2015
Objective: Much attention is paid to angiogenesis due to its mutual role in health and disease. Therefore, the effect of various chemical and physical agents on inhibition of this process has been recently studied. This study was conducted to investigate
Asadi-Samani, Majid., Baharara, Javad., Majidian Eydgahi, Shokat., Zafar Balanezhad, Saeideh.   +3 more
core   +1 more source

Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications

Cell Proliferation, Volume 58, Issue 10, October 2025.
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su, Yanlin Li, Zihao Zhou, Bing Feng, Haiming Chen, Guangjuan Zheng   +5 more
wiley   +1 more source

The Effects of Endogenous Hormones on the Flowering and Fruiting of Glycyrrhiza uralensis

Plants, 2019
Although endogenous hormones play an important role in flower bud differentiation and seed-filling, their effects on the flowering and fruiting of Glycyrrhiza uralensis Fisch. remain unknown.
Binbin Yan, Junling Hou, Jie Cui, Chao He, Wenbin Li, Xiaoyu Chen, Min Li, Wenquan Wang   +7 more
doaj   +1 more source

Hepatoprotective effect of total flavonoids from Glycyrrhiza uralensis Fisch in liver injury mice

Natural Product Research, 2020
This work aimed to investigate the hepatoprotective effect of total flavonoids from Glycyrrhiza uralensis. The main compounds in licorice total flavonoids (LTF) were isolated from Glycyrrhiza uralensis and their total content in LTF were more than 60%. Hepatoprotective effects of LTF were investigated in three kinds of hepatic injury mice model induced
San-Hu, Gou, Miao, He, Bei-Bei, Li, Ning-Yi, Zhu, Jing-Man, Ni   +4 more
openaire   +2 more sources

Emerging cGAS‐STING Agonist‐Based Nanotherapeutics: Mechanistic Insights and Applications in Cancer Combination Therapy

Advanced Science, Volume 12, Issue 36, September 25, 2025.
This review summarizes recent advances in cGAS‐STING agonist‐based nanotherapeutics for cancer combination therapy. It explores nanoparticle‐mediated delivery strategies, underlying molecular mechanisms, and combinatorial applications with chemotherapy, radiotherapy, targeted therapy, phototherapy, sonodynamic therapy, and immunotherapy.
Zhaomeng Wang, Yongjun Wang, Zhonggui He, Caigang Liu   +3 more
wiley   +1 more source