Results 11 to 20 of about 5,199 (177)

Therapeutic Effects of Glycyrrhizic Acid [PDF]

Natural Product Communications, 2013
Glycyrrhizic acid (GA), belonging to a class of triterpenes, is a conjugate of two molecules, namely glucuronic acid and glycyrrhetinic acid. It is naturally extracted from the roots of licorice plants.
Lee Jia Ming, Adeline Chia Yoke Yin
doaj   +3 more sources

Advances in the roles of glycyrrhizic acid in cancer therapy. [PDF]

Front Pharmacol, 2023
Since the first 70 years of reporting cancer chemotherapy, malignant tumors have been the second most common cause of death in children and adults. Currently, the commonly used anti-cancer methods include surgery, chemotherapy, radiotherapy, and immunotherapy. Although these treatment methods could alleviate cancer, they lead to different forms of side
Zhang Y, Sheng Z, Xiao J, Li Y, Huang J, Jia J, Zeng X, Li L.   +7 more
europepmc   +4 more sources

Treatment of Hematological Malignancies with Glycyrrhizic Acid [PDF]

Anticancer Research, 2017
The current study examined the effectiveness of glycyrrhizic acid (GA) in reducing cell viability and inducing apoptosis in human chronic myeloid leukemia (CML) in vitro and a mouse lymphoma in vivo. Additionally, we assessed GA as a candidate for combinational therapy in CML along with the current frontline treatment, imatinib (IM).
Bryan J, Hostetler, Olga N, Uchakina, Hao, Ban, Robert J, McKallip   +3 more
openaire   +2 more sources

Revealing the Toxicity-Enhancing Essence of Glycyrrhiza on Genkwa Flos Based on Ultra-high-performance Liquid Chromatography Coupled With Quadrupole-Orbitrap High-Resolution Mass Spectrometry and Self-Assembled Supramolecular Technology

Frontiers in Chemistry, 2021
Researchers often focus on the mechanisms of synergistic agents, a few explore drug combinations that enhance toxicity, while few have studied the internal mechanism of compatibility enhancement in chemical level.
Yuqin Yang, Feifei Li, Mengmeng Yan, Shan Chen, Desheng Cai, Xiaojing Liu, Nana Han, Zhihua Yuan, Jihui Lu, Yaozhi Zhang, Qiang Ma, Penglong Wang, Haimin Lei   +12 more
doaj   +1 more source

Clinical and morphological substantiation of the use of glycyrizzic acid in poultry farming [PDF]

BIO Web of Conferences
The paper presents a clinical and morphological justification for the use of glycyrrhizic acid in poultry farming. It was found that the use of glycyrrhizic acid in broiler chickens enhances the histological picture of the thymus with a pronounced image
Gatiyatullin Ildar, Bazekin George, Dolinin Ilgiz   +2 more
doaj   +1 more source

Using glycyrrhizic acid to target sumoylation processes during Epstein-Barr virus latency.

PLoS ONE, 2019
Cellular sumoylation processes are proposed targets for anti-viral and anti-cancer therapies. We reported that Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) dysregulates cellular sumoylation processes, contributing to its oncogenic potential ...
Gretchen L Bentz, Angela J Lowrey, Dustin C Horne, Vy Nguyen, Austin R Satterfield, Tabithia D Ross, Abigail E Harrod, Olga N Uchakina, Robert J McKallip   +8 more
doaj   +1 more source

Simultaneous determination of 12, 13-dihydroxyeuparin and glycyrrhizic acid in Yanyanfang mixture by high performance liquid chromatography

Journal of Pharmaceutical Analysis, 2011
A reversed phase high performance liquid chromatography (HPLC) method was established for the simultaneous determination of 12, 13-dihydroxyeuparin and glycyrrhizic acid in Yanyanfang mixture. A Grace Apollo C18 column (250 mm×4.6 mm, 5 μm) was used
Zhi-Sheng Xie, Xin-Jun Xu, Chun-Yan Xie, Jie-Yun Huang, Mei Yang, Rui-Ming Li, Xiao Chen   +6 more
doaj   +1 more source

Hepatoprotective properties of glycyrrhizic acid

Experimental and Clinical Gastroenterology, 2020
The review is devoted to the problem of treatment of non-alcoholic fatty liver disease, which is the most common pathology of the hepato-biliary system worldwide and is characterized by an increasing frequency, including of more severe forms. A wide range of pathogenetic relationships of non-alcoholic fatty liver disease with diseases of other organ ...
S. V. Okovity, K. L. Raikhelson, A. V. Volnukhin, D. A. Kudlai   +3 more
openaire   +2 more sources

Absorption and Interaction of the Main Constituents from the Traditional Chinese Drug Pair Shaoyao-Gancao via a Caco-2 Cell Monolayer Model

Molecules, 2012
Shaoyao-Gancao (Paeoniae Radix Alba and Glycyrrhizae Radix et Rhizoma) is a traditional Chinese drug pair widely used in decoctions for relieving pains, especially abdominal pain.
Qingqing Wu, Lianghui Chen, Yan Chen, Lu Wang, Jinyan Wang   +4 more
doaj   +1 more source

Synthesis of complex compounds of the monoammonium salt of glycyrrhizic acid and thiourea [PDF]

E3S Web of Conferences, 2023
With poor (low) solubility in the aquatic environment, highly toxic drugs (aspirin, doxorubicin, daunorubicin, sulfonamides and others), a low level of glycyrrhizic acid (HA) leads to a decrease in the toxicity of drugs and increases their biological ...
Askarov Ibrahim, Isaev Yusup, Tashtemirova Gulnoza, Rustamov Sanjar, Kadirov Mahamadzarif, Shadmanov Kamoliddin   +5 more
doaj   +1 more source