Using glycyrrhizic acid to target sumoylation processes during Epstein-Barr virus latency.
Cellular sumoylation processes are proposed targets for anti-viral and anti-cancer therapies. We reported that Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) dysregulates cellular sumoylation processes, contributing to its oncogenic potential ...
Gretchen L Bentz +8 more
doaj +2 more sources
Simultaneous determination of 12, 13-dihydroxyeuparin and glycyrrhizic acid in Yanyanfang mixture by high performance liquid chromatography [PDF]
A reversed phase high performance liquid chromatography (HPLC) method was established for the simultaneous determination of 12, 13-dihydroxyeuparin and glycyrrhizic acid in Yanyanfang mixture. A Grace Apollo C18 column (250 mmÃ4.6 mm, 5 μm) was used
Zhi-Sheng Xie +6 more
doaj +2 more sources
Glycyrrhizic acid has been used in Indian traditional medicine for ages. It is obtained from the root extract of Glycyrrhizaglabra. There is seasonal variation of Glycyrrhizic acid content in the roots of the plant.
Amit K De, S Datta, A Mukherjee
doaj +4 more sources
OPTIMIZATION OF HPLC METHODS FOR QUANTITATIVE DETERMINATION OF GLYCYRRHIZIC ACID IN LICORICE ROOTS [PDF]
Comparative evaluation of glycyrrhizic acid content in licorice roots by methods of UV-spectrophotometry (GF RF XIII) and high-performance liquid chromatography (HPLC) was carried out.
B. V. Brovchenko +4 more
doaj +1 more source
The main aim of this study was to enrich glycyrrhizic acid ammonium salt known as one of the main compounds of licorice roots (Glycyrrhiza glabra L.) by isoelectric focused adsorptive bubble separation technique with different foaming agents.
Eyyüp Karaoğul +3 more
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Glycerin as an alternative solvent for the extraction of glycyrrhizic acid from the roots of Glycyrrhiza glabra [PDF]
Licorice root extracts are one of the most common and widely used plant extracts. Due to the high content of biologically active substances and pronounced properties, they are used in various industries – in medicine, pharmacology, cosmetics and food ...
K. N. Laricheva, U. G. Grishina
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CO2 - extraction of glycyrrhizic acid from licorice root: Optimization of extraction conditions using RSM [PDF]
Extraction of GA (glycyrrhizic acid) from licorice roots was carried out utilizing SC-CO2 with etilen as a dissolvable. Tests and recreations were assigned utilizing RSM. Licorice root extricate was analyzed by chromatography and AAS.
Mirzayeva Shoxista +2 more
doaj +3 more sources
Glycyrrhizic acid attenuates cerebral ischemia-reperfusion injury in rats by inhibiting HMGB1-mediated pyroptosis [PDF]
Objective To explore the protective impact of glycyrrhizic acid on rats experiencing cerebral ischemia-reperfusion, and to elaborate its mechanism of action via high mobility group box-1 protein (HMGB1)- mediated pyroptosis.
CHEN Guolei +5 more
doaj +2 more sources
Objective This study aimed to evaluate a co-encapsulated pegylated nano-liposome system based on two herbal anti-tumor drugs, silibinin and glycyrrhizic acid, for delivery to a hepatocellular carcinoma (HCC) cell line (HepG2). Materials and Methods
Ochi Mohammad Mahdi +4 more
doaj +1 more source
AI-Assisted Engineering of Glycyrrhizic Acid/Simvastatin Nanocrystals for Multifunctional Treatment of Bacterial Osteomyelitis. [PDF]
Through AI‐assisted screening from FDA‐approved API to overcome the limitations of bacterial osteomyelitis treatment, glycyrrhizic acid and simvastatin are identified as a multifunctional combination capable of self‐assembling into mechanism‐targeting nanocrystals that effectively neutralize reactive oxygen species, suppress M1 macrophage polarization,
Han Y +11 more
europepmc +2 more sources

