Results 41 to 50 of about 2,494,579 (210)

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Glycyrrhizic acid treatment targets the maintenance of EBV latency.

, 2019
A) HEK 293 EBV BAC cells were treated with DMSO, ginkgolic acid, or graduated amounts of glycyrrhizic acid. Supernatant fluids were collected 72 hours post-treatment, DNase-resistant encapsidated virion associated DNA harvested, and real time PCR ...
Gretchen L. Bentz (6733994), Olga N. Uchakina (6734012), Vy Nguyen (4111945), Robert J. McKallip (6734015), Austin R. Satterfield (6734003), Tabithia D. Ross (6734006), Abigail E. Harrod (6734009), Angela J. Lowrey (6733997), Dustin C. Horne (6734000)   +8 more
core   +1 more source

AKR1C1 overexpression attenuates the inhibitory effect of glycyrrhizic acid on gastric cancer cell proliferation and migration [PDF]

, 2022
Purpose: To investigate the involvement of aldo-keto reductase family 1 member C1 (AKR1C1) in glycyrrhizic acid-mediated gastric cancer.Methods: Immunohistochemistry, quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR), and ...
Qiao, Lian, Gao, Junxia, Liu, Yalei, Shi, Cheng, Zheng, Qian   +4 more
core   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

A novel biomimetic nanomedicine system with anti-inflammatory and anti-osteoporosis effects improves the therapy efficacy of steroid-resistant nephrotic syndrome

Journal of Nanobiotechnology, 2021
Clinically, steroid-resistant nephrotic syndrome (SRNS) is always prolonged and difficult to treat and easily develops into end-stage renal disease, resulting in a low survival rate.
Jian Li, Mingyi Zhao, Xinying Xiang, Qingnan He, Rong Gui   +4 more
doaj   +1 more source

The Self-Assembly of Glycyrrhizic Acid into Nanofibrils

Journal of Colloid and Interface Science
The self-assembly of glycyrrhizic acid (GA) in aqueous solutions has significant implications for soft matter science and material design. Here, we describe the self-assembly of GA under well-defined conditions, focusing on measurements of the critical aggregation concentration (CAC) - when GA dimers start stacking into nanofibrils, and of the critical
Suelen Gauna Trindade, Fernando Bonin Okasaki, Ashley P. Williams, Edvaldo Sabadini, Viviane Lutz-Bueno   +4 more
openaire   +3 more sources

Protective effects of glycyrrhizic acid by rectal treatment on a TNBS-induced rat colitis model

, 2011
Objectives The research compared rectal and oral treatments with glycyrrhizic acid for trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats. Methods Wistar rats
Min Liu, Ying Liu, Robert J Lee, Hong Ding, Jin Xiang, Shi Wang   +5 more
core   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Pharmacological effect of Trinatrium salt of Glycyrrhizic acid

European Science Review, 2016
Trinatrium salt of glycyrrhizic acid (Glycytrinate) with strong anti-ulcerous activity combined with anti-inflammatory effect was synthesized on the basis of glycyrrhizic acid. According to the parameters of acute toxicity in experiments on white mice and rats with per oral administration Glycytrinate was included to the group of little toxic ...
MIRZAAKHMEDOVA KAMOLA TOKHIROVNA, AMINOV SALAKHITDIN DJURAYEVICH   +1 more
openaire   +2 more sources