Results 41 to 50 of about 5,199 (177)

Multi‐Induction Strategies in Crops: Mechanisms, Synergistic Effects, and Sustainable Applications for Enhanced Secondary Metabolite Production

Food Frontiers, Volume 7, Issue 4, July 2026.
This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun, Daoyan Xiao, Xingyue Li, Zhaofei Wang, Maoqin Xia, Chao Song, Hong‐Lei Li   +6 more
wiley   +1 more source

In Vitro Co-Delivery Evaluation of Novel Pegylated Nano-Liposomal Herbal Drugs of Silibinin and Glycyrrhizic Acid (Nano-Phytosome) to Hepatocellular Carcinoma Cells

Cell Journal, 2016
Objective This study aimed to evaluate a co-encapsulated pegylated nano-liposome system based on two herbal anti-tumor drugs, silibinin and glycyrrhizic acid, for delivery to a hepatocellular carcinoma (HCC) cell line (HepG2). Materials and Methods
Ochi Mohammad Mahdi, Amoabediny Ghasem, Rezayat Seyed Mahdi, Akbarzadeh Azim, Ebrahimi Bahman   +4 more
doaj  

Desenvolvimento e validação de métodos analíticos para determinação de ácido glicirrízico, ácido salicílico e cafeína em nanopartículas de quitosana e alginato

Química Nova, 2012
The present work consists of the development and validation of analytical method for evaluation of glycyrrhizic acid, salicylic acid, and caffeine in chitosan-alginate nanoparticles by high performance liquid chromatography.
Monika P. Tagliari, Andréa Granada, Gislaine Kuminek, Hellen K. Stulzer, Marcos A. S. Silva   +4 more
doaj   +1 more source

Food and Medicinal Homologous Substances in Sleep Disorders Improvement: Current Advances and Future Perspectives

Food Frontiers, Volume 7, Issue 4, July 2026.
The schematic diagram illustrating the improvement mechanisms of six typical FMH substances and their main active ingredients in different sleep disorders. ABSTRACT Sleep integrates many brain and peripheral processes, profoundly influencing well‐being.
Wenjing Wen, Qili Li, Chenghao Lv, Jing Wen, Yihan Zhang, Yuhang Yi, Tao Li, Fang Wang, Yibo Luo, Si Qin   +9 more
wiley   +1 more source

Transformation of Glycyrrhizic Acid byAspergillusspp.

Bioscience, Biotechnology, and Biochemistry, 1994
Glycryrrhizic acid was metabolized to 3-oxo-18β-glycyrrhetinic acid via 18β-glycyrrhetinic acid by Aspergillus niger, A. oryzae, A. sojae, and A. tamarii. Two methyl esters were derived from these two metabolites and identified by their 13C-NMR spectra and MS data.
Yamada, Yasumasa, Nakamura, Atsuko, Yamamoto, Kiyoko, Kikuzaki, Hiroe   +3 more
openaire   +1 more source

Autophagy Inhibition by Fangji Huangqi Decoction Enhances Tumor Immunogenicity and Potentiates PD‐1 Blockade

Cancer Science, Volume 117, Issue 7, Page 1778-1794, July 2026.
In tumor cells, MHC‐I is typically degraded through autophagy, leading to reduced antigen presentation. However, Fangji Huangqi Decoction (FJHQ), acting as an autophagy inhibitor, suppresses lysosomal acidification, which in turn inhibits the degradation of MHC‐I. This results in increased surface expression of MHC‐I on tumor cells.
Yuxiao Jiang, Shiji Zeng, Dingye Wang, Junbo Jiang, Zhenzhen Li, Jingbi Li, Dan Chen, Xu Zhao, Zheng Ying, Yuehua Deng, Qianwei Cai, Silin Mai, Jiayi Zheng, Qiaohong Yang, Fang Liu, Biaoyan Du, Jianyong Xiao, Xiaoyi Liu, Kun Wang   +18 more
wiley   +1 more source

Glycyrrhizic acid derivatives as Dengue virus inhibitors

Bioorganic & Medicinal Chemistry Letters, 2019
Dengue virus (DENV) is one of the most geographically distributed pathogenic flaviviruses transmitted by mosquitoes Aedes sps. In this study, the structure-antiviral activity relationships of Glycyrrhizic acid (GL) derivatives was evaluated by the inhibitory assays on the cytopathic effect (CPE) and viral infectivity of DENV type 2 (DENV2) in Vero E6 ...
Baltina, Lidia A., Tasi, Yan-Ting, Huang, Su-Hua, Lai, Hsueh-Chou, Baltina, Lia A., Petrova, Svetlana F., Yunusov, Marat S., Lin, Cheng-Wen   +7 more
openaire   +2 more sources

Nanobiotechnological Approaches to Enhance Potato Resistance against Potato Leafroll Virus (PLRV) Using Glycyrrhizic Acid Ammonium Salt and Salicylic Acid Nanoparticles

Horticulturae, 2021
The present research was aiming to study In-Silico the effect of Glycyrrhizic Acid ammonium salt (GAS) and Salicylic acid (SA) on the coat protein of potato leafroll virus (PLRV). In addition, in-vitro studying the effect of (GAS NPs) and Salicylic acid (
Tahsin Shoala, Ahmed A. Al-Karmalawy, Mousa O. Germoush, Salha M. ALshamrani, Mohamed A. Abdein, Nabil S. Awad   +5 more
doaj   +1 more source

Advancing Antiviral Design: Integrating Natural Products, Computation and Targeted Delivery

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
A stepwise translational framework linking natural‐product discovery, computational prioritisation, experimental validation, lead optimisation and targeted delivery is proposed to advance antiviral design. ABSTRACT The COVID‐19 pandemic highlighted the role of rapid viral mutation and global connectivity in accelerating viral emergence and spread ...
Adedayo Ayodeji Lanrewaju, Abimbola Motunrayo Folami, Saheed Sabiu, Feroz Mahomed Swalaha   +3 more
wiley   +1 more source

The Self-Assembly of Glycyrrhizic Acid into Nanofibrils

Journal of Colloid and Interface Science
The self-assembly of glycyrrhizic acid (GA) in aqueous solutions has significant implications for soft matter science and material design. Here, we describe the self-assembly of GA under well-defined conditions, focusing on measurements of the critical aggregation concentration (CAC) - when GA dimers start stacking into nanofibrils, and of the critical
Suelen Gauna Trindade, Fernando Bonin Okasaki, Ashley P. Williams, Edvaldo Sabadini, Viviane Lutz-Bueno   +4 more
openaire   +2 more sources