Results 41 to 50 of about 9,837 (271)

Characterization of high amylose starch-microcrystalline cellulose based floatable gel for enhanced gastrointestinal retention and drug delivery

Carbohydrate Polymer Technologies and Applications, 2022
Floatable high amylose rice starch and microcrystalline cellulose hybrid gels were developed for gastric drug delivery purposes. The concentration of microcrystal cellulose was varied from 1 to 4% to provide the porous rigid surface with high ...
L Susmita Devi, Arup Jyoti Das, Amit Baran Das   +2 more
doaj   +1 more source

Comparative Cytotoxicity of Glycyrrhiza glabra Roots from Different Geographical Origins Against Immortal Human Keratinocyte (HaCaT), Lung Adenocarcinoma (A549) and Liver Carcinoma (HepG2) Cells [PDF]

, 2015
Glycyrrhiza glabra L. (Fabaceae), commonly known as 'liquorice', is a well-known medicinal plant. Roots of this plant have long been used as a sweetening and flavouring agent in food and pharmaceutical products, and also as a traditional remedy for cough,
Akamatsu, Asha, Astafeva, Basar, Center, Dirican, Hirabayashi, Hiroaki, Hsieh, Kalaiarasi, Lakshmi, Li, Marianna, Marjan, Mosmann, Okimasu, Russo, Santos, Schmidt, Sharma, Song, Vispute, Yo, Zadeh, Zhang, Zheng, Zhou   +26 more
core   +1 more source

A novel biomimetic nanomedicine system with anti-inflammatory and anti-osteoporosis effects improves the therapy efficacy of steroid-resistant nephrotic syndrome

Journal of Nanobiotechnology, 2021
Clinically, steroid-resistant nephrotic syndrome (SRNS) is always prolonged and difficult to treat and easily develops into end-stage renal disease, resulting in a low survival rate.
Jian Li, Mingyi Zhao, Xinying Xiang, Qingnan He, Rong Gui   +4 more
doaj   +1 more source

Emerging trends in pharmacological and therapeutic potential of glycyrrhizic acids: Traditional and nanotechnological approach

Pharmacological Research - Modern Chinese Medicine
Introduction: Glycyrrhizic acid which is the most important active ingredient extracted from the licorice root shows great potential as a carrier material in traditional chinese medicine.
Priyanka Jurel, Shiv Bahadur, Meenakshi Bajpai   +2 more
doaj   +1 more source

Glycyrrhizic acid derivatives as Dengue virus inhibitors

Bioorganic & Medicinal Chemistry Letters, 2019
Dengue virus (DENV) is one of the most geographically distributed pathogenic flaviviruses transmitted by mosquitoes Aedes sps. In this study, the structure-antiviral activity relationships of Glycyrrhizic acid (GL) derivatives was evaluated by the inhibitory assays on the cytopathic effect (CPE) and viral infectivity of DENV type 2 (DENV2) in Vero E6 ...
Baltina, Lidia A., Tasi, Yan-Ting, Huang, Su-Hua, Lai, Hsueh-Chou, Baltina, Lia A., Petrova, Svetlana F., Yunusov, Marat S., Lin, Cheng-Wen   +7 more
openaire   +2 more sources

Mechanism of Cd-Induced Inhibition of Na-Glucose Cotransporter in Rabbit Proximal Tubule Cells: Roles of Luminal pH and Membrane-Bound Carbonic Anhydrase [PDF]

, 2008
Background/Aims: We have previously reported that a complex of cadmium-metallothionein (Cd-MT) directly affects the apical Na-glucose cotransporter on the luminal side in proximal tubules, suggesting that Cd-MT is more toxic than CdCl2 in causing ...
Fujimura Akio, Imai Masashi, Swenson Erik R., Tsuruoka Shuichi, 鶴岡 秀一   +4 more
core   +1 more source

The Interaction of the Transmembrane Domain of SARS-CoV-2 E-Protein with Glycyrrhizic Acid in Lipid Bilayer

Membranes, 2023
The interaction of the transmembrane domain of SARS-CoV-2 E-protein with glycyrrhizic acid in a model lipid bilayer (small isotropic bicelles) is demonstrated using various NMR techniques.
Polina A. Kononova, Olga Yu. Selyutina, Nikolay E. Polyakov   +2 more
doaj   +1 more source

Extraction of Glycyrrhizic Acid and Glabridin from Licorice [PDF]

International Journal of Molecular Sciences, 2008
The extraction and separation conditions of glycyrrhizic acid and glabridin from licorice were investigated. By changing the different extraction solvents, procedures, times and temperature, the optimum extraction condition was established: the used of ethanol/water (30:70, v/v) as an extraction solvent, and 60 min dipping time under 50°C. The extracts
Minglei Tian, Hongyuan Yan, Kyung Ho Row
openaire   +2 more sources

Enrichment of the Glycyrrhizic Acid from Licorice Roots (Glycyrrhiza glabra L.) by Isoelectric Focused Adsorptive Bubble Chromatography

Journal of Analytical Methods in Chemistry, 2016
The main aim of this study was to enrich glycyrrhizic acid ammonium salt known as one of the main compounds of licorice roots (Glycyrrhiza glabra L.) by isoelectric focused adsorptive bubble separation technique with different foaming agents.
Eyyüp Karaoğul, Perihan Parlar, Harun Parlar, M. Hakkı Alma   +3 more
doaj   +1 more source

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source