Results 71 to 80 of about 9,008 (236)

Peritoneal Lavage With Low GDP Neutral pH PD Solution Reduces Mortality and Severity in a Lethal Peritonitis Model

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction The efficacy of peritoneal lavage monotherapy using PD solution for severe peritonitis remains unproven. Methods We evaluated the effects of 3‐times and 6‐times lavage using low GDP neutral PD solution on a Methicillin‐sensitive Staphylococcus aureus (MSSA) lethal peritonitis model rats without antibiotic use.
Masato Ikeda, Kotaro Haruhara, Yukio Maruyama, Naoko Tanaka, Risa Kusanagi, Yuri Sakamaki, Hitomi Hagiwara, Takashi Yokoo   +7 more
wiley   +1 more source

Mechanism of Cd-Induced Inhibition of Na-Glucose Cotransporter in Rabbit Proximal Tubule Cells: Roles of Luminal pH and Membrane-Bound Carbonic Anhydrase [PDF]

, 2008
Background/Aims: We have previously reported that a complex of cadmium-metallothionein (Cd-MT) directly affects the apical Na-glucose cotransporter on the luminal side in proximal tubules, suggesting that Cd-MT is more toxic than CdCl2 in causing ...
Fujimura Akio, Imai Masashi, Swenson Erik R., Tsuruoka Shuichi, 鶴岡 秀一   +4 more
core   +1 more source

Desenvolvimento e validação de métodos analíticos para determinação de ácido glicirrízico, ácido salicílico e cafeína em nanopartículas de quitosana e alginato

Química Nova, 2012
The present work consists of the development and validation of analytical method for evaluation of glycyrrhizic acid, salicylic acid, and caffeine in chitosan-alginate nanoparticles by high performance liquid chromatography.
Monika P. Tagliari, Andréa Granada, Gislaine Kuminek, Hellen K. Stulzer, Marcos A. S. Silva   +4 more
doaj   +1 more source

Targeting acetylated high mobility group box 1 protein (HMGB1) and toll‐like receptor (TLR4) interaction to alleviate hypertension and neuroinflammation in fructose‐fed rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Our previous study reported that fructose intake increased systemic blood pressure and reduced nitric oxide (NO) in the nucleus tractus solitarius (NTS) due to oxidative stress and neuroinflammation. However, it remains unclear how reactive oxygen species (ROS) reduce NO and how this process impacts neuroinflammation in ...
Yu‐Te Lin, Chiu‐Yi Ho, Gwo‐Ching Sun, Tzyy‐Yue Wong, Michael Hsiao, Ching‐Jiunn Tseng, Pei‐Wen Cheng   +6 more
wiley   +1 more source

In Vitro Co-Delivery Evaluation of Novel Pegylated Nano-Liposomal Herbal Drugs of Silibinin and Glycyrrhizic Acid (Nano-Phytosome) to Hepatocellular Carcinoma Cells

Cell Journal, 2016
Objective This study aimed to evaluate a co-encapsulated pegylated nano-liposome system based on two herbal anti-tumor drugs, silibinin and glycyrrhizic acid, for delivery to a hepatocellular carcinoma (HCC) cell line (HepG2). Materials and Methods
Ochi Mohammad Mahdi, Amoabediny Ghasem, Rezayat Seyed Mahdi, Akbarzadeh Azim, Ebrahimi Bahman   +4 more
doaj  

Unveiling the catalytical roles of three glycosyltransferases in triterpenoid saponins in quinoa

Plant Biotechnology Journal, EarlyView.
Summary Saponins constitute a class of characteristic compounds within quinoa grains. In this study, metabolomic analysis identified 20 triterpene saponins, the majority of which were exclusively localized within the pericarp. Furthermore, three crucial glycosyltransferases were identified in quinoa.
Yiming Zhang, Peng Zhu, Long Wu, Zhaohui Li, Yongshun Huang, Mingyu Wang, Kaiying Gu, Peng Wang, Jun Li, Huihua Wan, Hailong Zhang, Jianghua Chen, Ruikun He, Wei Sun, Lixin Li   +14 more
wiley   +1 more source

Pharmacological effect of Trinatrium salt of Glycyrrhizic acid

European Science Review, 2016
Trinatrium salt of glycyrrhizic acid (Glycytrinate) with strong anti-ulcerous activity combined with anti-inflammatory effect was synthesized on the basis of glycyrrhizic acid. According to the parameters of acute toxicity in experiments on white mice and rats with per oral administration Glycytrinate was included to the group of little toxic ...
MIRZAAKHMEDOVA KAMOLA TOKHIROVNA, AMINOV SALAKHITDIN DJURAYEVICH   +1 more
openaire   +2 more sources

Synthesis and study of complexes of the novel Russian antiviral drug Camphecene with pentacyclic triterpenes of licorice [PDF]

, 2020
For the first time, the complexation of pentacyclic triterpenes of licorice (glycyrrhizic acid (GA) and its aglycone, glycyrrhetinic acid (GLA)) with the novel Russian antiviral drug Camphecene (Camph) was investigated.
Borisenko, N. I., Borisenko, S. N., Khizrieva, S. S., Maksimenko, E. V., Vetrova, E. V.   +4 more
core   +3 more sources

Comparison of the conventional and immersing powdered crude drugs (IPCD) methods for color and extraction of quantitative indicator ingredients in the Kampo formula decoction of daiokanzoto

Journal of Pharmaceutical Health Care and Sciences, 2023
Aim The immersing powdered crude drugs (IPCD) method is a quick and simple method for preparing decoctions. Here, the conventional and IPCD methods were compared for the color and extraction of quantitative indicator ingredients in the daiokanzoto ...
Kazumasa Naruhashi, Natsumi Amaike, Karen Shiraishi, Sumire Sato, Chiho Uryuzu, Yui Saito, Narumi Tsue   +6 more
doaj   +1 more source

Fatty Acids and Inflammatory Protein Biomarkers From Coronavirus Disease 2019 Patients

Immunity, Inflammation and Disease, Volume 13, Issue 7, July 2025.
The coronavirus disease 2019 (COVID‐19) pandemic created the need to identify new biomarkers and drug targets. In this study, we aimed to establish a unique signature profile of specific fatty acids, cytokines, and chemokines present in the plasma after COVID‐19 viral infection to serve as novel biomarkers that can be used to determine the severity of ...
Niharika Bala, Alaa H. Habib, Marianne Kozuch, Nancy D. Denslow, Neha S. Dhaliwal, Anna H. Owings, Sarah C. Glover, Abdel A. Alli   +7 more
wiley   +1 more source