Glycyrrhizin - Open Access .click

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Histamine release inhibition in anti-inflammatory mechanism [PDF]

, 1970
Rats were depleted of skin histamine by more than 80 % by intraperitoneal injections of sinomenine with daily increasing doses for 6 days. In these rats, egg-white edema induced in the hind paws was inhibited by 68 % of control. The weight of the wall of
Irino, Shozo +3 more
core +1 more source

Network pharmacology and in vitro experimental verification unveil glycyrrhizin from glycyrrhiza glabra alleviates acute pancreatitis via modulation of MAPK and STAT3 signaling pathways

BMC Complementary Medicine and Therapies
Acute pancreatitis (AP) is a severe gastrointestinal inflammatory disease with increasing mortality and morbidity. Glycyrrhiza glabra, commonly known as Liquorice, is a widely used plant containing bioactive compounds like Glycyrrhizin, which possesses ...
Rui Zhang +8 more
doaj +1 more source

The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis [PDF]

, 2015
In contrast to microbially triggered inflammation, mechanisms promoting sterile inflammation remain poorly understood. Damage-associated molecular patterns (DAMPs) are considered key inducers of sterile inflammation following cell death, but the relative
Antoine +17 more
core +1 more source

Nutritional Composition, Antioxidant Activity And Anticarcinogenic Effect Of Typhonium Flagelliforme (Nicholson 1029) Extract In Rat [PDF]

, 2000
Typhonium flagelliforme from the family Araceae is locally known as rodent tuber. It is being used traditionally in Malaysia to treat cancer. The major aim of this study was to investigate the effect of Typhonium flagelliforme crude extract on ...
Karuppiah, Thilakavathy
core

Dose-Dependent Pharmacokinetics of Glycyrrhizin in Rats.

Chemical and Pharmaceutical Bulletin, 1992
The dose-dependent pharmacokinetics of glycyrrhizin (GLZ) was investigated by measuring drug disappearance from plasma and biliary excretion in rats. The decline in plasma concentration was biexponential after an i.v. dose of 5, 10, 20, or 50 mg/kg. Dosage, however, had a marked effect on the pharmacokinetics, with a greater-than-proportional increase ...
S, Ishida, Y, Sakiya, T, Ichikawa, Z, Taira +3 more
openaire +3 more sources

Anti-inflammatory effects of intramammary infusions of glycyrrhizin in lactating cows with mastitis caused by coagulase-negative staphylococci [PDF]