Results 81 to 90 of about 10,603 (261)

Development and evaluation of sildenafil/glycyrrhizin-loaded nanofibers as a potential novel buccal delivery system for erectile dysfunction

open access: yesSaudi Pharmaceutical Journal
Erectile dysfunction (ED) is a growing health condition that needs safe and effective therapy. One of the main common treatments is sildenafil which is used in clinics for managing erectile dysfunction by enhancing the blood supply to the penis.
Ali A. Alamer   +8 more
doaj   +1 more source

A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis

open access: yesNature Communications, 2020
Saponins such as glycyrrhizin, a natural sweetener found in licorice root, are a class of triterpenoids synthesized that are characterized by a glucoronic acid moiety at the C-3 position.
Soo Yeon Chung   +8 more
doaj   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin   +17 more
wiley   +1 more source

Glycyrrhizin Represses Total Parenteral Nutrition-Associated Acute Liver Injury in Rats by Suppressing Endoplasmic Reticulum Stress

open access: yes, 2013
Total parenteral nutrition (TPN) is an artificial way to support daily nutritional requirements by bypassing the digestive system, but long-term TPN administration may cause severe liver dysfunction.
Hsing-Chun Kuo   +3 more
core   +1 more source

EFFECTS OF GLYCYRRHIZIN PRE-TREATMENT ON TRANSIENT ISCHEMIC BRAIN INJURY IN MICE

open access: yes, 2017
Background: Ischemia-induced brain damage is the leading cause of adult disability and the fifth leading cause of death, and thus, the development of anti-apoptotic neuro-protective therapeutic agents is viewed as an attractive developmental strategy ...
Kong, Bokcheul   +16 more
core   +1 more source

A leaf phenomics approach for estimating belowground traits in North American licorice

open access: yesAmerican Journal of Botany, Volume 113, Issue 5, May 2026.
Abstract Premise Selective breeding over thousands of years has prioritized aboveground yield, with little regard for changes belowground. Roots underpin plant growth and resilience, but our knowledge of these critical structures lags behind that of aboveground structures.
Zachary N. Harris   +5 more
wiley   +1 more source

The Protective Role of Glycyrrhizin on Ethanol- Damaged B92 Glial Cells in Vitro

open access: yesArmaghane Danesh Bimonthly Journal, 2019
Background & aim: Glycyrrhizin is one of the most important pharmacological compounds of the Licorice plant which has anti-inflammatory properties.
L Saleh Haggho   +2 more
doaj  

Diagnosis and Treatment of Foot Fusarium Infection Confirmed by Molecular Identification: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Fusarium spp. are opportunistic fungal pathogens, with an increasing incidence of infection observed in immunocompromised populations. Due to the non‐specific clinical manifestations of cutaneous Fusarium infections, they are often misdiagnosed or overlooked.
Yulin Wang   +9 more
wiley   +1 more source

EFFECT OF GLYCYRRHIZIN ON ESTROGEN ACTION

open access: yesEndocrinologia Japonica, 1967
It was demonstrated by the present study that glycyrrhizin inhibited the action of estradiol-17β on uterine weight and β-glucuronidase activity in ovariectomized mice and rats in a certain dose ratio. The inhibition was 50% or more when the dose ratio of glycyrrhizin: estradiol-17β was 1000: 1.
KUMAGAI, AKIRA   +4 more
openaire   +3 more sources

Polymorphic ventricular tachycardia (Torsades de pointes) due to licorice root tea

open access: yesTürk Kardiyoloji Derneği Arşivi, 2013
Longed QT syndromes are cardiac repolarization disorders characterized by longed QT intervals on ECG. This electrophysiological abnormality may lead to syncope or sudden cardiac death due to rapid, polymorphic ventricular tachycardia (VT). Licorice root (
Serkan Öztürk   +3 more
doaj   +1 more source

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