Results 191 to 200 of about 13,136 (253)
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Nanofibers of Glycyrrhizin/Hydroxypropyl-β-Cyclodextrin Inclusion Complex: Enhanced Solubility Profile and Anti-inflammatory Effect of Glycyrrhizin

AAPS PharmSciTech, 2023
Despite having a wide range of therapeutic advantages, glycyrrhizin (GL) has few commercial applications due to its poor aqueous solubility. In this study, we combined the benefits of hydroxypropyl β-cyclodextrin (HP-βCD) supramolecular inclusion ...
Jitu Halder   +6 more
semanticscholar   +1 more source

Potential Neuroprotective Effect of the HMGB1 Inhibitor Glycyrrhizin in Neurological Disorders

ACS Chemical Neuroscience, 2020
Glycyrrhizin (Glycyrrhizic Acid), a bioactive triterpenoid saponin found in Glycyrrhiza glabra, has been used for a long time in traditional medicine.
Yam Nath Paudel   +2 more
exaly   +2 more sources

Molecular docking, molecular dynamics simulation and MM-GBSA studies of the activity of glycyrrhizin relevant substructures on SARS-CoV-2 RNA-dependent-RNA polymerase

Journal of Biomolecular Structure and Dynamics, 2022
SARS-CoV-2 is the causative agent of Coronavirus Disease (COVID-19), which is a life-threatening disease. The World Health Organization has classified COVID-19 as a severe worldwide public health pandemic due to its high death rate, quick transmission ...
M. Zamzami
semanticscholar   +1 more source

Glycyrrhizin Mediates Downregulation of Notch Pathway Resulting in Initiation of Apoptosis and Disruption in the Cell Cycle Progression in Cervical Cancer Cells

Nutrition and Cancer, 2021
Growing emphasis on exploring the antiproliferative potential of natural compounds has gathered momentum for the formulation of anticancer drugs. In the present study, the anticancer and apoptotic potential of glycyrrhizin (GLY) was studied on HPV– C33A ...
Afza Ahmad   +4 more
semanticscholar   +1 more source

Glycyrrhizin: An old weapon against a novel coronavirus

Phytotherapy Research, 2020
Currently, over 100 countries are fighting against a common enemy, the severe acute respiratory syndrome coronavirus (SARS‐CoV)‐2, which causes COVID‐19.
J. Chrzanowski   +2 more
semanticscholar   +1 more source

A systematic review of experimental and clinical studies on the pharmacology of glycyrrhizin and its derivatives

Akusherstvo i ginekologiia, 2022
Glycyrrhizin and its derivatives (glycyrrhizic acid, etc.) are the key components of licorice root extracts (licorice) which can have anti-inflammatory and antiviral effects.
G. Gromova   +2 more
semanticscholar   +1 more source

Pharmacokinetics of magnesium glycyrrhizinate following intravenous administration of magnesium glycyrrhizinate in Rats

European Journal of Drug Metabolism and Pharmacokinetics, 2003
The elimination, distribution, excretion of magnesium glycyrrhizinate (MG) after intravenous (i.v.) administration in rats, and the binding rate of MG to plasma protein were investigated. The concentrations of MG in plasma, tissue, and excretion of rats after i.v.
Qin, Hu   +4 more
openaire   +2 more sources

Profound difference of metabolic pharmacokinetics between pure glycyrrhizin and glycyrrhizin in licorice decoction

Life Sciences, 2005
To investigate the difference of metabolic pharmacokinetics between pure glycyrrhizin (GZ) and GZ in licorice decoction, six New Zealand White rabbits were orally given pure GZ and licorice decoction containing equivalent content of GZ in a randomized crossover design.
Yu-Chi, Hou   +6 more
openaire   +2 more sources

Recent Advances in the Pharmacological Activities of Glycyrrhizin, Glycyrrhetinic Acid, and Their Analogs

Revista Brasileira de Farmacognosia, 2023
A. Mittal   +2 more
semanticscholar   +1 more source

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