Results 51 to 60 of about 13,136 (253)

Micelle Formation of Monoammonium Glycyrrhizinate

Journal of Oleo Science, 2021
Monoammonium glycyrrhizinate is produced by the neutralization of glycyrrhizic acid from plant licorice with ammonia. In this study, the physicochemical properties of aqueous monoammonium glycyrrhizinate were investigated from the viewpoint of surface chemistry.
Keisuke, Matsuoka, Mamoru, Arima, Yusuke, Goto, Shiho, Yada, Tomokazu, Yoshimura   +4 more
openaire   +3 more sources

Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

Food Frontiers, EarlyView.
Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou, Xuechun Sun, Jian Zhou, Huali Meng, Pengfei Fan, Yufeng Chu, Hao Wu   +6 more
wiley   +1 more source

LC-MS/MS standardization and validation of glycyrrhizin from the roots of Taverniera cuneifolia: A potential alternative source of Glycyrrhiza glabra

Heliyon, 2022
Glycyrrhizin is a triterpene glycoside derived from Glycyrrhiza glabra and related species which is a renowned phytochemical used to cure a variety of ailments such as inflammation, sore throat, hepatitis etc.
Padamnabhi S. Nagar, Shailendra Rane, Mannu Dwivedi   +2 more
doaj   +1 more source

Stabilization of solid lipid nanoparticles with glycyrrhizin

European Food Research and Technology, 2022
This study investigated the influence of saponin glycyrrhizin on the formation and stability of solid lipid nanoparticles. The hypothesis was that glycyrrhizin facilitates the formation of stable crystalline lipid particles due to its molecular ...
Hanna Salminen, Kadriye Nur Kasapoğlu, B. Özçelik, J. Weiss   +3 more
semanticscholar   +1 more source

Chewable Soft Gelatin Capsules: Design and Formulation Strategies for a Patient‐Preferred Dosage Alternative

Macromolecular Materials and Engineering, EarlyView.
Chewable softgels are a patient‐preferred alternative to conventional oral forms, offering pleasant taste, fast onset, and suitability for children or patients with swallowing difficulties. However, they present relevant challenges in their formulation: the shell must balance chewability, machinability, and stability, while the fill must mask the ...
Almudena Naharros‐Molinero, María Ángela Caballo‐González, Francisco Javier de la Mata, Sandra García‐Gallego   +3 more
wiley   +1 more source

Molecular screening of glycyrrhizin-based inhibitors against ACE2 host receptor of SARS-CoV-2

Journal of Molecular Modeling, 2021
The interaction between SARS-CoV-2 Spike protein and angiotensin-converting enzyme 2 (ACE2) is essential to viral attachment and the subsequent fusion process.
Sajjad Ahmad, Yasir Waheed, A. Abro, S. Abbasi, S. Ismail   +4 more
semanticscholar   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Effects of Glycyrrhizin in a Mouse Model of Lung Adenocarcinoma

Cellular Physiology and Biochemistry, 2017
Background: Currently, there is a global attempt to identify potential anti-cancer agents with low toxicity. Previous studies have found that glycyrrhizin exerts anti-cancer action with low toxicity through suppressing thromboxane A2 (TxA2) in lung ...
Qing-Ping Deng, Mao-Jie Wang, Xing Zeng, George Gong Chen, Run-Yue Huang   +4 more
doaj   +1 more source

Glycyrrhizin (Glycyrrhizic Acid) HMGB1 (high mobility group box 1) inhibitor upregulate mitochondrial function in adipocyte, cell viability and in-silico study

Journal of Saudi Chemical Society, 2022
Background: Mitochondrial plays a vital role in regulating obesity and related comorbidity. Targeting mitochondrial function could be a potent therapeutic approach to inhibit metabolic-related diseases like obesity, liver disease.
Md. Reyad-ul-Ferdous, Mohnad Abdalla, Yongfeng Song   +2 more
doaj   +1 more source

Glycyrrhizin regulates rat TMJOA progression by inhibiting the HMGB1‐RAGE/TLR4‐NF‐κB/AKT pathway

Journal of Cellular and Molecular Medicine, 2021
To investigate the role of glycyrrhizin on the progression of temporomandibular joint osteoarthritis (TMJOA) and the underlying mechanism by regulation of the high‐mobility group box 1 (HMGB1) receptor for advanced glycation end products (RAGE)/toll‐like
Zhi-hui Hu, M. Xiao, H. Cai, Wei Li, W. Fang, X. Long   +5 more
semanticscholar   +1 more source