Results 181 to 190 of about 11,518 (273)
Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.Abstract INTRODUCTION Agents targeting metabolic/vascular disorders are promising candidates to treat Alzheimer's disease (AD) and enhance safety and efficacy of other therapies. METHODS In a 2×2 factorial double‐blinded randomized trial, participants with mild cognitive impairment (MCI), early AD, or who were amyloid positive received intranasal ...
Jennifer M. Erichsen +11 more
wiley +1 more source
Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.Abstract Individuals with Down syndrome (DS) have a higher risk of developing cerebral amyloid angiopathy (CAA), primarily because of the excessive production of amyloid beta (Aβ). However, the consequences of CAA on blood–brain barrier (BBB) integrity and the neurovascular unit (NVU) are still not well understood.
Louis Valay, Marie‐Claude Potier
wiley +1 more source
“Hypodense Holes” and the Ocular Glymphatic System: Author Response: “Black Holes” and the Ocular Glymphatic System [PDF]
Investigative Opthalmology & Visual Science, 2017 Veva De Groot +6 more
openaire +4 more sources
Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.Abstract INTRODUCTION We examined the association between low‐frequency oscillations in blood pressure variability (LF‐BPV) at baseline (past) and 12 years later (concurrent) and BrainAGE gap (an indicator of brain health). METHODS Participants were 110 adults (age range 37–83 years at baseline, 60% female) from the Midlife in the United States (MIDUS)
Kevin S. Heffernan +6 more
wiley +1 more source
Annals of Neurology, Volume 98, Issue 4, Page 668-681, October 2025.Synthesis of Literature: Neurodegeneration in Moderate‐Severe TBI. [Color figure can be viewed at www.annalsofneurology.org] Objective Although moderate‐to‐severe traumatic brain injury (msTBI) was once considered a static neural event following resolution of acute injuries, numerous studies now demonstrate progressive losses to volume and white matter
Bhanu Sharma +4 more
wiley +1 more source
Cancer, Volume 131, Issue 19, 1 October 2025.Abstract Background The pathophysiology of chemotherapy‐induced cognitive impairment (CICI) remains unclear. Besides direct neurotoxicity, chemotherapy may trigger peripheral proinflammatory responses leading to neuroinflammation and neuronal injury.
Rob Colaes +10 more
wiley +1 more source
International Journal for Numerical Methods in Biomedical Engineering, Volume 41, Issue 10, October 2025.Ischemic stroke is a leading cause of death worldwide, yet clot lodging mechanics remain poorly understood. Most in silico studies assume a stress‐free clot, though both the clot and artery are likely in a pre‐stressed state at the point of thrombectomy procedures.
Jose L. Monclova +3 more
wiley +1 more source