Results 11 to 20 of about 28 (28)
Effect of anticholinergic eye drops on intraorbital, periorbital and brain pulsation power
Acta Ophthalmologica, EarlyView.Abstract Purpose The study aims to investigate the effect of pharmacologically reducing parasympathetic activity on ocular and cerebral pulsations, inspired by recent discoveries of a glymphatic‐like system in the eye driven by physiological pulsations.
Seyed Mohsen Ebrahimi +8 more
wiley +1 more source
Brain Pathology, EarlyView.Graphical representation of the widespread white matter (blue color mask) and grey matter (cortical and deep grey matter; red color mask) demyelination in MS cases characterized by substantial inflammation of the CP (A). The presence of lesions was mainly associated with periventricular white matter and hippocampus areas (A).
R. Magliozzi +19 more
wiley +1 more source
Exercise Delays Brain Ageing Through Muscle‐Brain Crosstalk
Cell Proliferation, EarlyView.This graphical abstract illustrates the reciprocal crosstalk between the brain and peripheral organs, highlighting the profound impact of exercise on brain health through systemic interactions. It underscores how exercise influences the brain via signals from various organs and, conversely, how the brain modulates functions of peripheral organs.
Shirin Pourteymour +3 more
wiley +1 more source
European Journal of Clinical Investigation, EarlyView.Abstract Background The validation of a combination of plasma biomarkers and demographic variables is required to establish reliable cut‐offs for Alzheimer's disease diagnosis (AD). Methods Plasma biomarkers (Aβ42/Aβ40, p‐Tau181, t‐Tau, NfL, GFAP), ApoE genotype, and demographic variables were obtained from a retrospective clinical cohort of cognitive ...
Lourdes Álvarez‐Sánchez +8 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Phosphorylated tau (pTau) has been reported in surgical resections in refractory epilepsy. It is unclear whether this is activity‐driven physiological pTau or signifies the advent of neurodegenerative cascades, relevant to memory decline.
Alicja Mrzyglod +13 more
wiley +1 more source
Anatomy of spinal CSF loss in the American alligator (Alligator mississippiensis)
Journal of Anatomy, Volume 246, Issue 4, Page 575-584, April 2025.India ink introduced into the cranial cerebrospinal fluid (CSF) compartment of Alligator diffuses along the spinal cord and exits the spinal compartment using perineural flow, resulting in a prominent “ink cuff” forming at the base of the spinal nerve. In Alligator, the region of the ink cuff is drained by a small lymphatic vessel.
Hadyn DeLeeuw +5 more
wiley +1 more source
Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dysfunction. This study aimed to describe the effects of shunt treatment on excessive daytime sleepiness and whether ...
Simon Lidén +4 more
wiley +1 more source
Changes to human sleep architecture during long‐duration spaceflight
Journal of Sleep Research, Volume 34, Issue 3, June 2025.Summary Both rapid eye movement and non‐rapid eye movement sleep are important for cognitive function and well‐being, yet few studies have examined whether human sleep architecture is affected by long‐duration spaceflight. We recorded 256 nights of sleep from five crew members before (n = 112 nights), during (n = 83 nights) and after (n = 61 nights) ~6‐
Oliver Piltch +3 more
wiley +1 more source
Objective sleep monitoring at home in older adults: A scoping review
Journal of Sleep Research, EarlyView.Summary Inadequate sleep in older adults is linked to health issues such as frailty, cognitive impairment and cardiovascular disorders. Maintaining regular sleep patterns is important for healthy aging, making effective sleep monitoring essential.
Sarah Nauman Ghazi +4 more
wiley +1 more source
Daily rhythm in DNA methylation and the effect of total sleep deprivation
Journal of Sleep Research, EarlyView.Summary Numerous hormones and genes exhibit diurnal 24‐hr rhythms that can also be affected by sleep deprivation. Here we studied diurnal rhythms in DNA methylation under a 24‐hr sleep/wake cycle and a subsequent 29 hr of continual wakefulness (1 night of sleep deprivation).
Antti‐Jussi Ämmälä +9 more
wiley +1 more source