Results 21 to 30 of about 24,909,638 (279)

Glymphatic system and post-hemorrhagic hydrocephalus

Brain Hemorrhages, 2023
The glymphatic system is a recently identified route for exchanging parenchyma interstitial fluid and cerebrospinal fluid along perivascular space, facilitating brain waste clearance.
Fenghui Ye, Richard F. Keep, Ya Hua, Hugh J.L. Garton, Guohua Xi   +4 more
doaj   +3 more sources

The Glymphatic System and Its Role in Neurovascular Diseases. [PDF]

J Neuroendovasc Ther
Over the past decade, clinicians and researchers have increasingly recognized the significance of the glymphatic system. Evidence demonstrates that this system—named for its reliance on astrocyte endfeet of glial cells and its lymphatic-like waste ...
Krings T, Takemoto Y, Mori K, Kee TP.
europepmc   +2 more sources

The Glymphatic System in Diabetes-Induced Dementia [PDF]

Frontiers in Neurology, 2018
The glymphatic system has emerged as an important player in central nervous system (CNS) diseases, by regulating the vasculature impairment, effectively controlling the clearance of toxic peptides, modulating activity of astrocytes, and being involved in
Young-Kook Kim, Young-Kook Kim, Kwang Il Nam, Juhyun Song, Juhyun Song   +4 more
doaj   +3 more sources

The glymphatic system and glioblastoma. [PDF]

Brain
Abstract The discovery of the glymphatic system and meningeal lymphatic vessels revolutionized the understanding of brain waste clearance. These findings challenged the long-held notion of CNS immune privilege and provided insights into how the brain maintains homeostasis despite lacking conventional lymphatic drainage.
Soumbasis A, Ueno A, Elliott D, Lama S, Edwards S, Starreveld YP, Zhang Y, Federico P, Sutherland GR, LeVan P, Poon CC.   +10 more
europepmc   +3 more sources

The glymphatic system in migraine and other headaches

The Journal of Headache and Pain
Glymphatic system is an emerging pathway of removing metabolic waste products and toxic solutes from the brain tissue. It is made of a network of perivascular spaces, filled in cerebrospinal and interstitial fluid, encompassing penetrating and pial ...
Maria Grazia Vittorini, A. Şahin, A. Trojan, Sevil Yusifli, Tamta Alashvili, G. Bonifácio, Ketevan Paposhvili, Viktoria Tischler, C. Lampl, S. Sacco   +9 more
semanticscholar   +5 more sources

The Glymphatic System and Pain [PDF]

Medical Acupuncture, 2020
The glymphatic system is network of perivascular spaces through which cerebrospinal fluid and interstitial fluid can move through the brain, clearing metabolic waste, such as amyloid beta, lactate and more, from the parenchyma. This cleaning system is regulated by sleep and norepinephrine, with increased levels of norepinephrine during wakefulness ...
Goldman, Nanna, Hablitz, Lauren M., Mori, Yuki, Nedergaard, Maiken   +3 more
openaire   +3 more sources

The glymphatic system: Current understanding and modeling [PDF]

iScience, 2022
We review theoretical and numerical models of the glymphatic system, which circulates cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models enable hypothesis development and predictions of transport, with clinical applications including drug delivery, stroke, cardiac arrest, and neurodegenerative disorders ...
Bohr, Tomas, Hjorth, Poul G., Holst, Sebastian C., Hrabětová, Sabina, Kiviniemi, Vesa, Lilius, Tuomas, Lundgaard, Iben, Mardal, Kent-Andre, Martens, Erik A., Mori, Yuki, Nägerl, U. Valentin, Nicholson, Charles, Tannenbaum, Allen, Thomas, John H., Tithof, Jeffrey, Benveniste, Helene, Iliff, Jeffrey J., Kelley, Douglas H., Nedergaard, Maiken   +18 more
openaire   +8 more sources

The glymphatic system in Huntington's disease. [PDF]

J Huntingtons Dis
The glymphatic system, a macroscopic waste clearance network in the brain, plays a vital role in maintaining neuronal health and brain homeostasis. Functionally analogous to the lymphatic system in other organs, the term “glymphatic” combines “glial” and “lymphatic.” This system facilitates the exchange of cerebrospinal fluid (CSF) and interstitial ...
Duan W, Zhou Y, Liu H.
europepmc   +4 more sources

Peristaltic flow in the glymphatic system [PDF]

Scientific Reports, 2020
AbstractThe flow inside the perivascular space (PVS) is modeled using a first-principles approach in order to investigate how the cerebrospinal fluid (CSF) enters the brain through a permeable layer of glial cells. Lubrication theory is employed to deal with the flow in the thin annular gap of the perivascular space between an impermeable artery and ...
Romano, Francesco, Suresh, Vinod, Galie, Peter A., Grotberg, James B.   +3 more
openaire   +5 more sources

Continuous Theta-Burst Stimulation Promotes Paravascular CSF-Interstitial Fluid Exchange through Regulation of Aquaporin-4 Polarization in APP/PS1 Mice

Mediators of Inflammation, 2022
Amyloid-β (Aβ) deposition plays a crucial role in the occurrence and development of Alzheimer’s disease (AD), and impaired Aβ clearance is the leading cause of Aβ deposition.
Cheng Wu, Tuo Lin, Qian Ding, Ni Zhang, Zi-tong Ou, Gui-yuan Cai, Hong-ying Chen, Jia-yue Xu, Ge Li, Zhong Pei, Guang-qing Xu, Yue Lan   +11 more
doaj   +1 more source