Results 21 to 30 of about 18,116,541 (240)

Impairment of the glymphatic system after diabetes [PDF]

open access: yesJournal of Cerebral Blood Flow & Metabolism, 2016
The glymphatic system has recently been shown to clear brain extracellular solutes and abnormalities in glymphatic clearance system may contribute to both initiation and progression of neurological diseases. Despite that diabetes is known as a risk factor for vascular diseases, little is known how diabetes affects the glymphatic system.
Jiang, Quan   +9 more
openaire   +4 more sources

Glymphatic system: a gateway for neuroinflammation

open access: yesNeural Regeneration Research, 2023
The glymphatic system is a relatively recently identified fluid exchange and transport system in the brain. Accumulating evidence indicates that glymphatic function is impaired not only in central nervous system disorders but also in systemic diseases ...
Kailu Zou   +3 more
doaj   +3 more sources

Magnetic Resonance Imaging and Modeling of the Glymphatic System

open access: yesDiagnostics, 2020
The glymphatic system is a newly discovered waste drainage pathway in the brain; it plays an important role in many neurological diseases. Ongoing research utilizing various cerebrospinal fluid tracer infusions, either directly or indirectly into the ...
Jasleen Kaur   +8 more
doaj   +3 more sources

Glymphatic system and post-hemorrhagic hydrocephalus

open access: yesBrain Hemorrhages, 2023
The glymphatic system is a recently identified route for exchanging parenchyma interstitial fluid and cerebrospinal fluid along perivascular space, facilitating brain waste clearance.
Fenghui Ye   +4 more
doaj   +3 more sources

The glymphatic system in migraine and other headaches [PDF]

open access: yesThe Journal of Headache and Pain
AbstractGlymphatic system is an emerging pathway of removing metabolic waste products and toxic solutes from the brain tissue. It is made of a network of perivascular spaces, filled in cerebrospinal and interstitial fluid, encompassing penetrating and pial vessels and communicating with the subarachnoid space.
Maria Grazia Vittorini   +10 more
openaire   +5 more sources

The glymphatic system and Amyotrophic lateral sclerosis

open access: yesProgress in Neurobiology
The glymphatic system and the meningeal lymphatic vessels provide a pathway for transport of solutes and clearance of toxic material from the brain. Of specific relevance to ALS, this is applicable for TDP-43 and glutamate, both major elements in disease pathogenesis.
Eisen, Andrew   +3 more
openaire   +4 more sources

The glymphatic system and glioblastoma. [PDF]

open access: yesBrain
Abstract The discovery of the glymphatic system and meningeal lymphatic vessels revolutionized the understanding of brain waste clearance. These findings challenged the long-held notion of CNS immune privilege and provided insights into how the brain maintains homeostasis despite lacking conventional lymphatic drainage.
Soumbasis A   +10 more
europepmc   +3 more sources

Dysfunction of the Glymphatic System as a Potential Mechanism of Perioperative Neurocognitive Disorders

open access: yesFrontiers in Aging Neuroscience, 2021
Perioperative neurocognitive disorder (PND) frequently occurs in the elderly as a severe postoperative complication and is characterized by a decline in cognitive function that impairs memory, attention, and other cognitive domains.
Xuli Ren   +7 more
doaj   +1 more source

The Brain’s Glymphatic System: Drawing New Perspectives in Neuroscience

open access: yesBrain Sciences, 2023
This paper delves into the intricate structure and functionality of the brain’s glymphatic system, bringing forth new dimensions in its neuroscientific understanding.
Alexandru Vlad Ciurea   +4 more
doaj   +1 more source

The glymphatic system: Current understanding and modeling [PDF]

open access: yesiScience, 2022
We review theoretical and numerical models of the glymphatic system, which circulates cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models enable hypothesis development and predictions of transport, with clinical applications including drug delivery, stroke, cardiac arrest, and neurodegenerative disorders ...
Bohr, Tomas   +18 more
openaire   +8 more sources

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