Results 31 to 40 of about 24,909,638 (279)

A clinical primer for the glymphatic system

open access: yesBrain, 2021
Abstract The complex and dynamic system of fluid flow through the perivascular and interstitial spaces of the CNS has new-found implications for neurological diseases. CSF movement throughout the CNS parenchyma is more dynamic than could be explained via passive diffusion mechanisms alone.
Lucas P Carlstrom   +9 more
openaire   +2 more sources

Mapping the Glymphatic Pathway Using Imaging Advances

open access: yesJ, 2023
The glymphatic system is a newly discovered waste-clearing system that is analogous to the lymphatic system in our central nervous system. Furthermore, disruption in the glymphatic system has also been associated with many neurodegenerative disorders (e ...
Rajvi N. Thakkar   +6 more
doaj   +1 more source

What Is the “Glymphatic System”?

open access: yesMagnetic Resonance in Medical Sciences, 2023
Although the glymphatic system hypothesis is highly popular, it also lacks certain details. In this paper, an attempt was made to present a more clearly defined hypothesis, which is consistent with the past experiment results. The new hypothesis consists of (1) water flux in the brain parenchyma, (2) water and solutes pathway of the perivascular space,
openaire   +3 more sources

Imaging glymphatic response to glioblastoma

open access: yesCancer Imaging, 2023
Background The glymphatic system actively exchanges cerebrospinal fluid (CSF) and interstitial fluid (ISF) to eliminate toxic interstitial waste solutes from the brain parenchyma.
Jasleen Kaur   +11 more
doaj   +1 more source

MRI-Based Demonstration of the Normal Glymphatic System in a Human Population: A Systematic Review

open access: yesFrontiers in Neurology, 2022
BackgroundThe glymphatic system has been described as one that facilitates the exchange between the cerebrospinal fluid (CSF) and interstitial fluid, and many recent studies have demonstrated glymphatic flow based on magnetic resonance imaging (MRI).
Min Kyoung Lee   +3 more
doaj   +1 more source

The Glymphatic System: a Potential Key Player in Bacterial Meningitis

open access: yesmBio, 2022
The glial-lymphatic system (glymphatic system) is a recently characterized fluid clearance pathway of the central nervous system. Glymphatic system disfunctions leading to defects in drainage of the cerebrospinal fluid have been associated with several ...
Marco Rinaldo Oggioni, Uwe Koedel
doaj   +1 more source

The Role of Glymphatic System in Alzheimer’s and Parkinson’s Disease Pathogenesis

open access: yesBiomedicines, 2022
Alzheimer’s disease (AD) is the most common cause of neurodegenerative dementia, whilst Parkinson’s disease (PD) is a neurodegenerative movement disorder.
Francesca R. Buccellato   +4 more
doaj   +1 more source

MRI and glymphatic system [PDF]

open access: yesStroke and Vascular Neurology, 2019
Glymphatic system is newly discovered pseudolymphatic system in brain and it plays an important role in the removal of interstitial metabolic waste products. We discuss and review the role of glymphatic system in neurological diseases, especially focus on the potential of MRI modelling and its associated challenges to obtain useful new information ...
openaire   +2 more sources

Altered Glymphatic System in Middle-Aged cART-Treated Patients With HIV: A Diffusion Tensor Imaging Study

open access: yesFrontiers in Neurology, 2022
Objective:The brain relies on the glymphatic system to clear metabolic wastes and maintain brain homeostasis to fulfill its functions better. Yet, the complexity of the glymphatic flow and clearance and its changes in HIV infection and its role in ...
Benedictor Alexander Nguchu   +8 more
doaj   +1 more source

The Brain’s Glymphatic System: Current Controversies [PDF]

open access: yesTrends in Neurosciences, 2020
The glymphatic concept along with the discovery of meningeal lymphatic vessels have, in recent years, highlighted that fluid is directionally transported within the central nervous system (CNS). Imaging studies, as well as manipulations of fluid transport, point to a key role of the glymphatic-lymphatic system in clearance of amyloid-β and other ...
Mestre, Humberto   +2 more
openaire   +3 more sources

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