Results 31 to 40 of about 17,183,881 (176)

Glymphatic imaging using MRI [PDF]

, 2020
In recent years, the existence of a mass transport system in the brain via cerebrospinal fluid (CSF) or interstitial fluid (ISF) has been suggested by many studies.
Toshiaki Taoka, Shinji Naganawa, Taoka, Toshiaki, Naganawa, Shinji   +3 more
core   +1 more source

Peristaltic flow in the glymphatic system [PDF]

Scientific Reports, 2020
AbstractThe flow inside the perivascular space (PVS) is modeled using a first-principles approach in order to investigate how the cerebrospinal fluid (CSF) enters the brain through a permeable layer of glial cells. Lubrication theory is employed to deal with the flow in the thin annular gap of the perivascular space between an impermeable artery and ...
Romano, Francesco, Suresh, Vinod, Galie, Peter A., Grotberg, James B.   +3 more
openaire   +5 more sources

Continuous Theta-Burst Stimulation Promotes Paravascular CSF-Interstitial Fluid Exchange through Regulation of Aquaporin-4 Polarization in APP/PS1 Mice

Mediators of Inflammation, 2022
Amyloid-β (Aβ) deposition plays a crucial role in the occurrence and development of Alzheimer’s disease (AD), and impaired Aβ clearance is the leading cause of Aβ deposition.
Cheng Wu, Tuo Lin, Qian Ding, Ni Zhang, Zi-tong Ou, Gui-yuan Cai, Hong-ying Chen, Jia-yue Xu, Ge Li, Zhong Pei, Guang-qing Xu, Yue Lan   +11 more
doaj   +1 more source

Mapping the Glymphatic Pathway Using Imaging Advances

J, 2023
The glymphatic system is a newly discovered waste-clearing system that is analogous to the lymphatic system in our central nervous system. Furthermore, disruption in the glymphatic system has also been associated with many neurodegenerative disorders (e ...
Rajvi N. Thakkar, Ivelina P. Kioutchoukova, Ian Griffin, Devon T. Foster, Pratiksha Sharma, Eduardo Molina Valero, Brandon Lucke-Wold   +6 more
doaj   +1 more source

What Is the “Glymphatic System”?

Magnetic Resonance in Medical Sciences, 2023
Although the glymphatic system hypothesis is highly popular, it also lacks certain details. In this paper, an attempt was made to present a more clearly defined hypothesis, which is consistent with the past experiment results. The new hypothesis consists of (1) water flux in the brain parenchyma, (2) water and solutes pathway of the perivascular space,
openaire   +3 more sources

MRI-Based Demonstration of the Normal Glymphatic System in a Human Population: A Systematic Review

Frontiers in Neurology, 2022
BackgroundThe glymphatic system has been described as one that facilitates the exchange between the cerebrospinal fluid (CSF) and interstitial fluid, and many recent studies have demonstrated glymphatic flow based on magnetic resonance imaging (MRI).
Min Kyoung Lee, Se Jin Cho, Yun Jung Bae, Jong-Min Kim   +3 more
doaj   +1 more source

The Glymphatic System: A Beginner’s Guide [PDF]

Neurochemical Research, 2015
The glymphatic system is a recently discovered macroscopic waste clearance system that utilizes a unique system of perivascular tunnels, formed by astroglial cells, to promote efficient elimination of soluble proteins and metabolites from the central nervous system.
Nadia Aalling Jessen, Anne Sofie Finmann Munk, Iben Lundgaard, Maiken Nedergaard   +3 more
openaire   +2 more sources

Altered Glymphatic System in Middle-Aged cART-Treated Patients With HIV: A Diffusion Tensor Imaging Study

Frontiers in Neurology, 2022
Objective:The brain relies on the glymphatic system to clear metabolic wastes and maintain brain homeostasis to fulfill its functions better. Yet, the complexity of the glymphatic flow and clearance and its changes in HIV infection and its role in ...
Benedictor Alexander Nguchu, Jing Zhao, Jing Zhao, Yanming Wang, Jean de Dieu Uwisengeyimana, Xiaoxiao Wang, Bensheng Qiu, Hongjun Li, Hongjun Li   +8 more
doaj   +1 more source

Age- and glaucoma-induced changes to the ocular glymphatic system

, 2023
The ocular glymphatic system supports bidirectional fluid transport along the optic nerve, thereby removes metabolic wastes including amyloid-β.
Sun, Qian, Richard T. Libby, Sweeney, Amanda, Shinya Sakurai, Libby, Richard T., Sigurdsson, Björn, Christine Delle, Peter Kusk, Delle, Christine, Maiken Nedergaard, Nedergaard, Maiken, Weiguo Peng, Qian Sun, Kusk, Peter, Björn Sigurdsson, Wang, Xiaowei, Peng, Weiguo, Amanda Sweeney, Plá, Virginia, Ting Du, Giannetto, Michael, Michael Giannetto, Du, Ting, Virginia Plá, Sakurai, Shinya, Xiaowei Wang   +25 more
core   +1 more source

Glymphatic System Dysfunction and Sleep Disturbance May Contribute to the Pathogenesis and Progression of Parkinson’s Disease

, 2022
Parkinson’s disease (PD) is a multisystem alpha-synucleinopathic neurodegenerative disease and the most prevalent neurodegenerative disorder after Alzheimer’s disease with a high incidence rate in the elderly population.
Andie Massey, Khoo, Tien K., Boag, Matthew K, Dharah Bispo, Pountney, Dean L, Matthew Boag, Scott-Massey, Andie, Bispo, Dharah P. C. F., Annie Magnier, Bispo, Dharah PCF, Boag, Matthew K., Pountney, Dean L., Khoo, Tien K, Dean Pountney, Magnier, Annie, Tien Khoo   +15 more
core   +1 more source