The Glymphatic System: a Potential Key Player in Bacterial Meningitis [PDF]
mBio, 2022 The glial-lymphatic system (glymphatic system) is a recently characterized fluid clearance pathway of the central nervous system. Glymphatic system disfunctions leading to defects in drainage of the cerebrospinal fluid have been associated with several ...
Marco Rinaldo Oggioni, Uwe Koedel
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The glymphatic system clears amyloid beta and tau from brain to plasma in humans [PDF]
Nature CommunicationsDysfunction of the glymphatic system has been proposed as a mechanistic link between sleep disruption and Alzheimer’s disease (AD). In animal models, glymphatic impairment alone can drive AD pathology. Whether this system clears amyloid beta (Aβ) and tau
Paul Dagum +13 more
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The Glymphatic System in Diabetes-Induced Dementia [PDF]
Frontiers in Neurology, 2018 The glymphatic system has emerged as an important player in central nervous system (CNS) diseases, by regulating the vasculature impairment, effectively controlling the clearance of toxic peptides, modulating activity of astrocytes, and being involved in
Young-Kook Kim +4 more
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Neurobiology of DiseaseNeurodegenerative diseases (ND) are characterized by the accumulation of aggregated proteins. The glymphatic system, through its rapid exchange mechanisms between cerebrospinal fluid (CSF) and interstitial fluid (ISF), facilitates the movement of ...
Yan-rui Sun +4 more
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Glymphatic system function in patients with ischemic stroke evaluated by the DTI-ALPS method: a comprehensive review [PDF]
Frontiers in NeurologyThe glymphatic system is a glial-dependent waste clearance pathway in the central nervous system (CNS) of vertebrates that exploits the perivascular compartment between the vascular basement membrane (outermost wall of blood vessels) and astrocytic ...
Lichuan Zeng +8 more
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Targeting the glymphatic system: Aβ accumulation and phototherapy strategies across different stages of Alzheimer’s disease [PDF]
Translational NeurodegenerationThe glymphatic system serves as the brain’s clearance system. It deteriorates with age and is a significant contributor to the onset and progression of Alzheimer’s disease (AD).
Danrui Zhao +11 more
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Research hotspots and frontiers of glymphatic system and Alzheimer's disease: a bibliometrics analysis. [PDF]
Front Aging NeurosciLiu S, Zhuang L, Li X.
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Dilated Virchow-Robin spaces in primary open-angle glaucoma : a biomarker of glymphatic waste clearance dysfunction? [PDF]
, 2016 The lymphatic clearance pathways of the brain are different compared to the other organs of the body and have been the subject of heated debates. Drainage of brain extracellular fluids, particularly interstitial fluid (ISF) and cerebrospinal fluid (CSF),
Audenaert, Kurt +5 more
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The Glymphatic System：a New Exploration of Pathological Mechanism in Stroke [PDF]
Zhongguo quanke yixue, 2022 The glymphatic system is a system that promotes the exchange and flow of cerebrospinal fluid (CSF) -interstitial fluid (ISF) to maintain the balance of CSF-ISF, and rid the neuropil of toxic proteinaceous metabolites with astroglial water channel ...
YI Ting, JIN Shuoguo, YIN Haiyan, GAO Ping, ZHU Tianmin
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Development of a novel diagnostic model for Alzheimer's disease based on glymphatic system and metabolism-related genes. [PDF]
Front Mol BiosciJiang A +9 more
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