Glymphatic system dysfunction in young adults hospitalized for an acute psychotic episode: a preliminary report from a pilot study [PDF]
The glymphatic system is integral to the elimination of metabolic waste from the central nervous system and has been extensively studied in relation to neurodegenerative and cerebrovascular diseases. Emerging evidence suggests that glymphatic dysfunction
Tommaso Barlattani +11 more
doaj +2 more sources
Effects of intermittent theta-burst stimulation on cognition and glymphatic system activity in mild cognitive impairment and very mild Alzheimer’s disease: a randomized controlled trial [PDF]
Background Repetitive transcranial magnetic stimulation (rTMS) has demonstrated efficacy in alleviating cognitive symptoms in Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Although animal studies suggest rTMS may enhance glymphatic system
Cheng-Chang Yang +5 more
doaj +2 more sources
Optoacoustic imaging of the glymphatic system
Background: The glymphatic system is a brain waste clearance system mediated via cerebrospinal fluid (CSF) flow,1 with implications for influence on neurodegenerative diseases.2 Most preclinical glymphatic studies employ fluorescence imaging, which provides higher specificity, but a smaller field-of-view (FOV), or magnetic resonance imaging (MRI ...
Sarah Shaykevich +7 more
openalex +4 more sources
The Glymphatic System:a New Exploration of Pathological Mechanism in Stroke [PDF]
The glymphatic system is a system that promotes the exchange and flow of cerebrospinal fluid (CSF) -interstitial fluid (ISF) to maintain the balance of CSF-ISF, and rid the neuropil of toxic proteinaceous metabolites with astroglial water channel ...
YI Ting, JIN Shuoguo, YIN Haiyan, GAO Ping, ZHU Tianmin
doaj +1 more source
Glymphatic System Dysfunction in Central Nervous System Diseases and Mood Disorders
The glymphatic system, a recently discovered macroscopic waste removal system in the brain, has many unknown aspects, especially its driving forces and relationship with sleep, and thus further explorations of the relationship between the glymphatic ...
Dianjun Zhang +8 more
doaj +1 more source
The glymphatic system in Huntington's disease. [PDF]
The glymphatic system, a macroscopic waste clearance network in the brain, plays a vital role in maintaining neuronal health and brain homeostasis. Functionally analogous to the lymphatic system in other organs, the term “glymphatic” combines “glial” and “lymphatic.” This system facilitates the exchange of cerebrospinal fluid (CSF) and interstitial ...
Duan W, Zhou Y, Liu H.
europepmc +3 more sources
The Glymphatic System and Pain [PDF]
The glymphatic system is network of perivascular spaces through which cerebrospinal fluid and interstitial fluid can move through the brain, clearing metabolic waste, such as amyloid beta, lactate and more, from the parenchyma. This cleaning system is regulated by sleep and norepinephrine, with increased levels of norepinephrine during wakefulness ...
Goldman, Nanna +3 more
openaire +4 more sources
"Black Holes" and the Ocular Glymphatic System: Author Response to "The Glymphatic System: A New Player in Ocular Diseases?" [PDF]
Denniston, AK, Keane, PA
core +5 more sources
The glymphatic system: Current understanding and modeling [PDF]
We review theoretical and numerical models of the glymphatic system, which circulates cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models enable hypothesis development and predictions of transport, with clinical applications including drug delivery, stroke, cardiac arrest, and neurodegenerative disorders ...
Bohr, Tomas +18 more
openaire +8 more sources
Peristaltic flow in the glymphatic system [PDF]
AbstractThe flow inside the perivascular space (PVS) is modeled using a first-principles approach in order to investigate how the cerebrospinal fluid (CSF) enters the brain through a permeable layer of glial cells. Lubrication theory is employed to deal with the flow in the thin annular gap of the perivascular space between an impermeable artery and ...
Romano, Francesco +3 more
openaire +6 more sources

