Results 11 to 20 of about 5,928 (179)

Oxyanion and tetrahedral intermediate stabilization by subtilisin : detection of a new tetrahedral adduct [PDF]

, 2009
The peptide-derived glyoxal inhibitor Z-Ala-Ala-Phe-glyoxal has been shown to be ~10 fold more effective as an inhibitor of subtilisin than Z-Ala-Pro-Phe-glyoxal. Signals at 107.2 p.p.m. and 200.5 p.p.m.
Rogers, Louis, Howe, Nicole, Hewage, Chandralal, Malthouse, J.Paul G.   +3 more
core   +1 more source

Glyoxal damages human aortic endothelial cells by perturbing the glutathione, mitochondrial membrane potential, and mitogen-activated protein kinase pathways

BMC Cardiovascular Disorders, 2021
Background Exposure to glyoxal, the smallest dialdehyde, is associated with several diseases; humans are routinely exposed to glyoxal because of its ubiquitous presence in foods and the environment.
Ming-Zhang Xie, Chun Guo, Jia-Qi Dong, Jie Zhang, Ke-Tao Sun, Guang-Jian Lu, Lei Wang, De-Ying Bo, Lu-Yang Jiao, Guo-An Zhao   +9 more
doaj   +1 more source

Revisiting the global budget of atmospheric glyoxal: updates on terrestrial and marine precursor emissions, chemistry, and impacts on atmospheric oxidation capacity [PDF]

Atmospheric Chemistry and Physics
Atmospheric glyoxal (CHOCHO) plays critical yet incompletely understood roles in tropospheric chemistry. Current models substantially underestimate glyoxal abundance over both land and ocean, indicating knowledge gaps in our understanding of its sources ...
A. Zhang, A. Zhang, A. Zhang, T.-M. Fu, T.-M. Fu, T.-M. Fu, T.-M. Fu, Y. Wang, E. Xiong, E. Xiong, E. Xiong, E. Xiong, W. Wu, W. Wu, W. Wu, W. Wu, Y. Li, L. Zhu, L. Zhu, L. Zhu, W. Tao, W. Tao, W. Tao, K. C. Wells, D. B. Millet, Z. Wang, B. Yuan, M. Shao, C. Lerot, C. Lerot, T. Danckaert, R. Zhang, K. H. Bates   +32 more
doaj   +1 more source

Simulation of semi-explicit mechanisms of SOA formation from glyoxal in aerosol in a 3-D model [PDF]

Atmospheric Chemistry and Physics, 2014
New pathways to form secondary organic aerosol (SOA) have been postulated recently. Glyoxal, the smallest dicarbonyl, is one of the proposed precursors.
C. Knote, A. Hodzic, J. L. Jimenez, R. Volkamer, J. J. Orlando, S. Baidar, J. Brioude, J. Fast, D. R. Gentner, A. H. Goldstein, P. L. Hayes, W. B. Knighton, H. Oetjen, A. Setyan, H. Stark, R. Thalman, G. Tyndall, R. Washenfelder, E. Waxman, Q. Zhang   +19 more
doaj   +1 more source

Chamber studies of SOA formation from aromatic hydrocarbons: observation of limited glyoxal uptake [PDF]

Atmospheric Chemistry and Physics, 2012
This study evaluates the significance of glyoxal acting as an intermediate species leading to secondary organic aerosol (SOA) formation from aromatic hydrocarbon photooxidation under humid conditions. Rapid SOA formation from glyoxal uptake onto aqueous (
S. Nakao, Y. Liu, P. Tang, C.-L. Chen, J. Zhang, D. R. Cocker III   +5 more
doaj   +1 more source

Glyoxal-based fixation of Drosophila embryos for immunofluorescence staining and RNA in situ hybridization

STAR Protocols, 2023
Summary: The dialdehyde glyoxal is an alternative chemical fixative that cross-links tissues faster than formaldehyde, retains higher antigenicity, and is less hazardous than either formaldehyde or glutaraldehyde. Here we present a glyoxal-based fixation
Shrunali Amin, Malika Basu, Valeria Buzinova, Anthony Delgado, Tejas Mahadevan, Sanya Mishra, Sarah Zaida, Xi Wang, Anna Marie Sokac   +8 more
doaj   +1 more source

Glyoxal in hyperglycaemic ischemic stroke – a cohort study

Cardiovascular Diabetology, 2023
Background Hyperglycaemia is frequent in acute ischemic stroke and denotes a bad prognosis, even in the absence of pre-existing diabetes. However, in clinical trials treatment of elevated glucose levels with insulin did not improve stroke outcome ...
Sina Rhein, Julica Inderhees, Oliver Herrmann, Alaa Othman, Kimberly Begemann, Thomas Fleming, Peter P. Nawroth, Karel D. Klika, Rakad Isa, Inke R. König, Georg Royl, Markus Schwaninger   +11 more
doaj   +1 more source

A Retrieval of Glyoxal from OMI over China: Investigation of the Effects of Tropospheric NO2

Remote Sensing, 2019
East China is the ‘hotspot’ of glyoxal (CHOCHO), especially over the Pearl River Delta (PRD) region, where glyoxal is yielded from the oxidation of aromatics.
Yapeng Wang, Jinhua Tao, Liangxiao Cheng, Chao Yu, Zifeng Wang, Liangfu Chen   +5 more
doaj   +1 more source

Chemical insights, explicit chemistry, and yields of secondary organic aerosol from OH radical oxidation of methylglyoxal and glyoxal in the aqueous phase [PDF]

Atmospheric Chemistry and Physics, 2013
Atmospherically abundant, volatile water-soluble organic compounds formed through gas-phase chemistry (e.g., glyoxal (C2), methylglyoxal (C3), and acetic acid) have great potential to form secondary organic aerosol (SOA) via aqueous chemistry in clouds ...
Y. B. Lim, Y. Tan, B. J. Turpin
doaj   +1 more source

Seasonal in situ observations of glyoxal and methylglyoxal over the temperate oceans of the Southern Hemisphere [PDF]

Atmospheric Chemistry and Physics, 2015
The dicarbonyls glyoxal and methylglyoxal have been measured with 2,4-dinitrophenylhydrazine (2,4-DNPH) cartridges and high-performance liquid chromatography (HPLC), optimised for dicarbonyl detection, in clean marine air over the temperate Southern ...
S. J. Lawson, P. W. Selleck, I. E. Galbally, M. D. Keywood, M. J. Harvey, C. Lerot, D. Helmig, Z. Ristovski   +7 more
doaj   +1 more source