Results 101 to 110 of about 29,848 (251)

Lifespan‐Extending Endogenous Metabolites

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

Organic Acids: The Pools of Fixed Carbon Involved in Redox Regulation and Energy Balance in Higher Plants

open access: yesFrontiers in Plant Science, 2016
Organic acids are synthesized in plants as a result of the incomplete oxidation of photosynthetic products and represent the stored pools of fixed carbon accumulated due to different transient times of conversion of carbon compounds in metabolic pathways.
Abir U Igamberdiev   +1 more
doaj   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

open access: yesThe FEBS Journal, Volume 293, Issue 3, Page 781-805, February 2026.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

The Transcription Factor StuA Regulates the Glyoxylate Cycle in the Dermatophyte Trichophyton rubrum under Carbon Starvation. [PDF]

open access: yesInt J Mol Sci, 2023
Petrucelli MF   +5 more
europepmc   +1 more source

SWEET1‐mediated glucose transport is crucial for energy availability in Arabidopsis

open access: yesNew Phytologist, Volume 249, Issue 4, Page 1816-1830, February 2026.
Summary The stress‐responsive hormone abscisic acid (ABA) is known for its inhibitory effects on various physiological processes, including seed germination, often resulting in energy deprivation. Interestingly, ABA‐induced germination inhibition can be alleviated by exogenous glucose (Glc), mimicking a functional interplay between ABA and sugar ...
Xueyi Xue   +3 more
wiley   +1 more source

Metabolome Atlas of Brain Reveals Regional Shared and Unique Metabolic Drifts in Response to Type 2 Diabetes in Male Mice

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
A detailed metabolome atlas of the male mouse brain was established, incorporating metabolomic and lipidomic profiling of seven anatomical regions. T2D induced marked metabolic alterations, which were mainly associated with lipotoxicity, defective energy metabolism, proinflammatory processes, and neurotoxicity.
Yang Zhou   +5 more
wiley   +1 more source

Characterization of the GPR1/FUN34/YaaH protein family in the green microalga Chlamydomonas suggests their role as intracellular membrane acetate channels

open access: yesPlant Direct, 2019
The unicellular green microalga Chlamydomonas reinhardtii is a powerful photosynthetic model organism which is capable of heterotrophic growth on acetate as a sole carbon source.
Lorenzo Durante   +3 more
doaj   +1 more source

Pomegranate (Punica granatum L.) Fruits: Characterization of the Main Enzymatic Antioxidants (Peroxisomal Catalase and SOD Isozymes) and the NADPH-Regenerating System

open access: yesAgronomy, 2019
Pomegranate (Punica granatum L.) is a common edible fruit. Its juice can be used as a source of antioxidative compounds, primarily polyphenols and vitamin C, in addition to other vitamins and minerals.
Melisa Pinilla   +4 more
doaj   +1 more source

Microbiological Production of Citric and Isocitric Acids from Sunflower Oil

open access: yesFood Technology and Biotechnology, 2008
The growth of wild type strain Yarrowia lipolytica VKM Y-2373 and its mutant Yarrowia lipolytica N 15 as well the biosynthesis of citric and isocitric acids on sunflower oil were studied.
Svetlana V. Kamzolova   +2 more
doaj  

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