Results 11 to 20 of about 1,028 (203)
Catalytic Nucleophilic Glyoxylation of Aldehydes [PDF]
Organic Letters, 2010 β-Silyloxy-α-ketoesters are prepared through a cyanide-catalyzed benzoin-type reaction with silyl glyoxylates and aldehydes. The products undergo a dynamic kinetic resolution to provide enantioenriched orthogonally protected alcohols and can be converted to the corresponding β-silyloxy-α-aminoesters.
Kimberly M, Steward, Jeffrey S, Johnson
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CATALYTIC MULTI-COMPONENT COUPLING REACTIONS OF SILYL GLYOXYLATES [PDF]
, 2022 Described is the development of catalytic, stereoselective reactions of silyl glyoxylates utilizing Rh(I)-catalyzed additions of aryl boronic acids. This reactivity was translated asymmetrically via additional effort from our laboratory resulting in the ...
Turman, Nolan Clark
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Complexity-Building Transformations of Silyl Glyoxylates [PDF]
, 2011 Silyl glyoxylates are reagents used for the geminal difunctionalization of a glycolic acid junction with nucleophilic and electrophilic species. The research summarized herein describes the development of new reactions that utilize silyl glyoxylates to ...
Schmitt, Daniel Copley
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Vinylogous Michael cascade reactions employing silyl glyoxylates and silyl glyoximides [PDF]
, 2011 I. Vinylation-Initiated Vinylogous Michael Cascade of Silyl Glyoxylates and Elaboration to Nitrocyclopentanols: An investigation of the reaction parameters required to achieve a vinylation-initiated vinylogous Michael cascade of silyl glyoxylates and ...
Boyce, Gregory Ronald
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Catalytic Redox-Initiated Glycolate Aldol Additions of Silyl Glyoxylates [PDF]
, 2009 Lanthanide triisopropoxides catalyze a rapid, tandem MPV reduction/Brook rearrangement/aldol sequence between silyl glyoxylates and aldehydes that achieves catalytic turnover through alkoxide transfer from a strain-release Lewis acidic ...
Greszler, Stephen N. +1 more
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I. Catalytic redox-initiated glycolate aldol additions of silyl glyoxylates II. Diastereoselective De Novo Synthesis of pentasubstituted gamma-butyrolactones from silyl glyoxylates and ketones via double Reformatsky reactions III. Progress toward the total synthesis of leustroducsin B [PDF]
, 2010 I. Catalytic Redox-Initiated Glycolate Aldol Additions of Silyl Glyoxylates An investigation of the reaction parameters necessary for achieving a catalytic redox-initiated glycolate aldol addition of silyl glyoxylates and metal alkoxides was performed ...
Greszler, Stephen Nathaniel
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, 2022 A Lewis-acid-catalyzed selective reaction between anilines and glyoxylates was developed for synthesis of diarylmethanes or oxoimidazolidines. Under the catalysis of AgOTf, a series of anilines-based diarylmethanes, including primary, secondary, and ...
Zhixiong Jin +13 more
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, 2016 An efficient Friedel−Crafts reaction of a series of 2-substituted thiophenes with alkyl glyoxylates has been developed using a catalytic amount of an easy accessible 6,6′-dibromo-BINOL/Ti(IV) complex.
Janusz Jurczak (1470880) +2 more
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, 2016 The three-component coupling of Mg acetylides, silyl glyoxylates, and nitroalkenes results in a highly diastereoselective Kuwajima–Reich/vinylogous Michael cascade that provides tetrasubstituted silyloxyallene products.
Gregory R. Boyce (2121970) +2 more
core +3 more sources
Robustness in Glyoxylate Bypass Regulation
PLoS Computational Biology, 2009 The glyoxylate bypass allows Escherichia coli to grow on carbon sources with only two carbons by bypassing the loss of carbons as CO(2) in the tricarboxylic acid cycle. The flux toward this bypass is regulated by the phosphorylation of the enzyme isocitrate dehydrogenase (IDH) by a bifunctional kinase-phosphatase called IDHKP.
Guy Shinar +2 more
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