Results 261 to 270 of about 157,757 (356)

Vaccine preparedness for Bundibugyo virus and lessons learned. [PDF]

NPJ Vaccines
Pletschette M, Biedenkopf N.
europepmc   +1 more source

The rising tide: Trends in induction of labor at term over a 5‐year period at a single centre

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 383-390, April 2025.
Abstract Objective Induction of labor (IOL) is a controversial topic in contemporary obstetric practice, with some suggesting that the increase in elective induction (eIOL) as a potential contributor to increasing cesarean delivery (CD) rates. The objectives of this single‐center study were to examine the rates of IOL, trends in indications for IOL ...
Sarah M. Nicholson, Susan Hatt, Etaoin M. Kent, Michael P. Geary, Patrick Dicker, Zara E. Molphy, Karen Flood, Fergal D. Malone   +7 more
wiley   +1 more source

An IgM monoclonal antibody targeting diguanylate cyclase DgcE potentiates gentamicin activity against avian pathogenic Escherichia coli through modulation of c-di-GMP signaling. [PDF]

BMC Vet Res
Fangfang L, Lianhua N, Haiyang W, Zhihao W, Liyan L, Jiangang H, Yuanzheng J, Yinli B, Xiangan H, Haidong W.   +9 more
europepmc   +1 more source

A multicenter analysis of 1364 elective/rescue cerclages in Brazil: Perinatal outcomes, complications, and the role of vaginal progesterone

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate perinatal outcomes in women undergoing cervical cerclage for prevention of preterm birth in Brazilian maternity hospitals. Methods This retrospective cohort study included 1364 women with singleton pregnancies who underwent elective or rescue cervical cerclage between December 2003 and November 2025.
Isabella C. Bragheto, Gabriela M. Pereira, Camila Mirandez, Marcelo Luis Nomura, Elton Carlos Ferreira, Rodolfo C. de Pacagnella, Evelyn Traina, Danilo B. Silva, Karayna Gil Fernandes, Julia Negro, Conrado M. Coutinho, Manuella R. Pereira, Janete Vettorazzi, Julia Hubner, Edson Vieira Cunha Filho, Ellen M. Arlindo, Aluana R. Parola, Pedro D. Correa, Renato Passini Junior, Renato T. Souza   +19 more
wiley   +1 more source

The versatility of the CHASE domain in one-component systems of c-di-GMP signal transduction from <i>P. aeruginosa</i>. [PDF]

J Bacteriol
Angeli S, Scribani-Rossi C, Colasanto G, Spizzichino S, Rosignoli S, Giorgi A, Cutruzzolà F, Paone A, Tramonti A, Contestabile R, Montoya R, O'Toole GA, Paiardini A, Rinaldo S.   +13 more
europepmc   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Mechanical forces in bacterial pathogenesis: Sensing, tropism, and intervention. [PDF]

Virulence
Jiang Y, Xu G, Liang H, Wang Y, Liu G, Pan X, Yang L, Liu H, Liu Y, Ren Y, Wang X, Shi Q.   +11 more
europepmc   +1 more source

Advances in Immunological Combination Therapy for Colorectal Cancer

iMetaMed, EarlyView.
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu, Rongbo Wen, Tianshuai Zhang, Fuao Cao, Xiaoming Zhu, Liqiang Hao, Wei Zhang, Guanyu Yu   +7 more
wiley   +1 more source

Machine learning-driven discovery of therapeutic nucleoside hydrogels for periodontitis. [PDF]

Int J Oral Sci
Li W, Wen Y, Huang Z, Shuai F, Yin Y, Chen Q, Zhu F, Xu H, Zhao H.   +8 more
europepmc   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source