Results 241 to 250 of about 157,757 (356)

Left ventricular function improvement during angiotensin receptor–neprilysin inhibitor treatment in a cohort of HFrEF/HFmrEF patients

ESC Heart Failure, Volume 12, Issue 2, Page 1151-1165, April 2025.
Prediction of LVEF improvement in patients with HFrEF and HFmrEF following treatment with Sacubitril/Valsartan. Workflow of this study investigating the functional capacity improvement in response to Sacubitrail/Valsartsan in a real‐world scenario of heart failure treatment.
Florian Appenzeller, Tobias Harm, Manuel Sigle, Parwez Aidery, Klaus‐Peter Kreisselmeier, Livia Baas, Andreas Goldschmied, Meinrad Paul Gawaz, Karin Anne Lydia Müller   +8 more
wiley   +1 more source

Allosteric Activation through Coordinated Energy Landscape Reweighting and Information Flow. [PDF]

Comput Struct Biotechnol J
Zhang BD, Zhao DR, Liu MT, Yang LQ, Sang P.   +4 more
europepmc   +1 more source

AraC-like transcriptional activator CuxR binds c-di-GMP by a PilZ-like mechanism to regulate extracellular polysaccharide production

Proceedings of the National Academy of Sciences of the United States of America, 2017
Simon Schäper, Wieland Steinchen, E. Krol, F. Altegoer, Dorota Skotnicka, L. Søgaard‐Andersen, G. Bange, A. Becker   +7 more
semanticscholar   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

A global stress alarmone couples nutrient limitation to suppression of social signaling in bacteria. [PDF]

iScience
Gondu P, Verma RK, Bhattacharjee C, Mohanty AK, Chatterjee S.   +4 more
europepmc   +1 more source

Analysis and Classification of Partial Shading Conditions in Photovoltaic Arrays

Energy Science &Engineering, EarlyView.
This study presents new mathematical models for describing P–V curve extrema under different shading scenarios and applies machine learning classifiers that use features derived from P–V characteristics for accurate fault identification. ABSTRACT With the escalating global transition toward renewable energy, ensuring the operational stability and ...
Hamid Reza Parsa, Mohammad Sarvi
wiley   +1 more source

Phosphodiesterase BpdE suppress bacterial proliferation by regulating <i>min</i> operon in <i>Brucella abortus</i>. [PDF]

Front Microbiol
Chen J, Dong Z, Liu W, Zu Y, Liu W, Zhou D, Jin Y, Wang A.   +7 more
europepmc   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility. [PDF]

Mol Microbiol
Mohaghegh F, Scadden J, Baker MAB.
europepmc   +1 more source

Cyclic di-GMP Regulates TfoY in Vibrio cholerae To Control Motility by both Transcriptional and Posttranscriptional Mechanisms

Journal of Bacteriology, 2018
Benjamin R Pursley, M. Maiden, M. Hsieh, Nicolas L. Fernandez, Geoffrey B. Severin, C. Waters   +5 more
semanticscholar   +1 more source