Results 231 to 240 of about 189,721 (306)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Protocol to identify the signaling network of nucleotide second messengers in Shigella sonnei. [PDF]

STAR Protoc
Cui B, Chen X, Wang M, Deng Y.
europepmc   +1 more source

A Case for Anti‐IgE Vaccination

Allergy, EarlyView.
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff, Zahra Gharailoo, Monique Vogel, Martin F. Bachmann   +3 more
wiley   +1 more source

Personalized, digitally designed 3D-Printed protein substitutes: Advancing medical food for PKU patients. [PDF]

Curr Res Food Sci
Marcello F, Baratian Ghorghi Z, Russo GL, Ferraioli A, Cavella S, Di Monaco R.   +5 more
europepmc   +1 more source

Polypropylene Nanoplastic Exposure to Respiratory Epithelial Barrier‐On‐Chip and Interfacial Interactions With Human Serum Albumin

Allergy, EarlyView.
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert, Eyup Bilgi, Reyhan Coban, Pelin Saglam‐Metiner, Basar Dogan, Zeynep Imir‐Tekneci, Suleyman Selim Cinaroglu, Ozlem Goksel, Ceyda Oksel Karakus, Ozlem Yesil‐Celiktas   +9 more
wiley   +1 more source

A decade of innovation in healthcare: Automation, bio-printing and digital twin technologies for personalized therapies. [PDF]

Int J Pharm X
Ghavami D, Giulietti N, Sandri G, Giberti H.   +3 more
europepmc   +1 more source

Rapid evolution of Klebsiella pneumoniae biofilms in vitro delineates adaptive changes selected during infection. [PDF]

Nat Commun
Zaborskytė G, Coelho P, Wrande M, Sandegren L.   +3 more
europepmc   +1 more source

PeriOperative Quality Initiative consensus statement recommendations on the definitions, aims and delivery of shared decision‐making for major surgery

Anaesthesia, EarlyView.
Summary Introduction Shared decision‐making is a collaborative process whereby clinicians and patients work together to decide on a treatment plan that is informed by evidence, clinical experience and individual patient characteristics and preferences. This process is particularly important for complex surgical decisions when the risks and benefits of ...
Debra Leung, Alf Collins, Jennifer Philip, Michael P. W. Grocott, Bernhard Riedel, Denny Z. H. Levett, on behalf of the PeriOperative Quality Initiative XVIII (POQI XVIII) Workgroup, Nina Abild Frederiksen, Peter Alkemade, Ianthe Boden, Mark Boughey, Meg Chiswell, Rohit D'Costa, Jeremy Fernando, Diane Fisher, Tammy C Hoffmann, Hilmy Ismail, Richard Kelly, Telena Kerkham, Smaro Lazarakis, Ailsa McKitterick‐Gillett, Rory Ormiston, Joanne Shafer, Mieka Tabart, Phong Tran, David Wang, David Watters, Elliot Wollner   +27 more
wiley   +1 more source

Impact of facility based versus home based growth monitoring and promotion programs on child nutritional status in rural Bangladesh. [PDF]

Sci Rep
Hossain M, Haque MA, Faruque ASG, Bulbul MMI, Ahmed T, Ashorn U, Ashorn P.   +6 more
europepmc   +1 more source