The rising tide: Trends in induction of labor at term over a 5‐year period at a single centre
Abstract Objective Induction of labor (IOL) is a controversial topic in contemporary obstetric practice, with some suggesting that the increase in elective induction (eIOL) as a potential contributor to increasing cesarean delivery (CD) rates. The objectives of this single‐center study were to examine the rates of IOL, trends in indications for IOL ...
Sarah M. Nicholson +7 more
wiley +1 more source
Identification of poplar and spruce GDP-mannose pyrophosphorylases involved in mannan and ascorbic acid biosynthesis. [PDF]
Guevara-Rozo S, Mansfield SD.
europepmc +1 more source
Abstract Objective To evaluate perinatal outcomes in women undergoing cervical cerclage for prevention of preterm birth in Brazilian maternity hospitals. Methods This retrospective cohort study included 1364 women with singleton pregnancies who underwent elective or rescue cervical cerclage between December 2003 and November 2025.
Isabella C. Bragheto +19 more
wiley +1 more source
Tangential flow filtration as a novel approach for fluorescent tracer purification and production up-scaling: cetuximab-800CW and ustekinumab-800CW as a proof-of-concept. [PDF]
Huizinga HK +8 more
europepmc +1 more source
ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang +5 more
wiley +1 more source
Bridging preclinical development and clinical manufacturing: a translational GMP-Platform for lentiviral vector production in academic CAR T-Cell therapy. [PDF]
Lara-Chica M +12 more
europepmc +1 more source
S100A8/A9 Drives Emergency Granulopoiesis to Promote Triple‐Negative Breast Cancer Metastasis
ABSTRACT Objective Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential and limited therapeutic options. Although neutrophils contribute to tumor progression, how tumors systemically regulate neutrophil production remains poorly understood.
Hami Hemati +5 more
wiley +1 more source
Identification of genetic determinants that promote biofilm growth under heterotrophic conditions in <i>Cupriavidus necator</i> using transposon enrichment. [PDF]
Weiler JR, Lapp CJ, Gescher J, Edel M.
europepmc +1 more source
Repeated Exposure to a Hair Bleaching Mixture Alters cGAS–STING Pathway Transcripts in Mice
ABSTRACT Hair bleaching products commonly contain ammonia and hydrogen peroxide, chemicals capable of generating reactive oxygen species (ROS). However, their effects on innate immune signaling pathways associated with DNA damage remain poorly understood.
Leticia Rodrigues Sampaio +2 more
wiley +1 more source

