Results 211 to 220 of about 117,081 (314)

Navigating CAR-T translation in Australia: lessons from an academic program. [PDF]

Front Med (Lausanne)
Tan RPA, Walsh R, McCowage G, O'Neill GM, Gowrishankar K.   +4 more
europepmc   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Biofilm-mediated antibiotic tolerance in bacterial pathogens: Integrated molecular networks and novel therapeutic avenues. [PDF]

Virulence
Zou W, Lin R, Zhao Y, Zhan P, Zhao X, Zhang Q.   +5 more
europepmc   +1 more source

A Practical Formulation for Seismic Damage Accumulation on Multiple Mainshock‐Aftershock Sequences Based on Disaggregation of the Mainshock Hazard

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Earthquakes often occur in clusters (foreshocks, mainshocks, and aftershocks) and can lead to cumulative structural damage. Many studies have extended traditional performance‐based earthquake engineering (PBEE) to account for damage accumulation in multiple mainshock‐aftershock (MS‐AS) sequences using Markov chain processes and state‐dependent
Babak Ghods, A. H. M. Muntasir Billah
wiley   +1 more source

Participation of the Transcriptional Regulator Fur in Modulating Biofilm Formation of the Salmonid Pathogen <i>Yersinia ruckeri</i>: Beyond Iron Homeostasis. [PDF]

Int J Mol Sci
Peñaloza D, Barros MJ, Cabezas-Mera F, Acuña LG, Vásquez-Arriagada P, Parra F, Queraltó C, Silva C, Díaz S, Ubilla C, Moya-Beltrán A, Silva A, Nevermann J, Parada P, Gil F, Fuentes JA, Calderón IL.   +16 more
europepmc   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Diverse Biological Functions and Domain-Specific Interactions of the Diguanylate Cyclase PA2072 in <i>Pseudomonas aeruginosa</i> PAO1. [PDF]

Int J Microbiol
Gao X, Zhang Y, Guo L, Zhang H, Sun J, Sun J, Huang W.   +6 more
europepmc   +1 more source

Electrochemical Valence‐Regulated Biomimetic Nanozymes for Breast Cancer Metabolism Inhibition and Potentiated Catalytic Immunotherapy

Exploration, EarlyView.
MnOx nanozymes face low tumoricidal activity and PD‐L1‐mediated immune attenuation. Electrochemically regulated M‐MnOx with high oxidase activity was TCM‐wrapped into TMO. TMO targets tumors, triggers ICD, activates cGAS‐STING, antagonizes PD‐L1, and suppresses tumor recurrence, providing new insights for Mn‐based nanomaterials.
You Pan, Wei Cai, Meng Suo, Xiangqin Meng, Shengxin Ye, Yuping Tan, Xianqing Wei, Mingpu Yang, Pengyuan Qi, Zihang Yu, Kelong Fan, Shipeng Ning   +11 more
wiley   +1 more source

Growth monitoring and promotion uptake and its associated factors among mothers/ caregivers of children aged under two years in Wondo District, Ethiopia: Cross-sectional Study. [PDF]

PLoS One
Negash T, Bolka A, Kare AP, Feleke FW, Bosha T.   +4 more
europepmc   +1 more source