Results 101 to 110 of about 75,810 (239)

Feminizing Therapy in People With Klinefelter Syndrome and Gender Incongruence: Considerations for Treatment Without Testosterone Blockers

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS; 47, XXY) usually involves male sex development and gender identity. Small studies suggest gender incongruence may be more common in KS, but feminizing gender‑affirming hormone therapy in this group has been scarcely reported.
Maaike Kroon, Tamira Klaziene Klooker, Sabine Elisabeth Hannema, Martin Den Heijer   +3 more
wiley   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

GnRH-E1 RNA is localized in the GT1-7 neuron nucleus.

, 2016
(A) Schematic diagram of the conserved regulatory elements upstream of the mouse Gnrh1 TSS, which contains enhancers 1, 2, and 3 (E3, E2, E1, respectively), the promoter (P), and the Gnrh1 gene with four exons (white boxes).
Liza E. Brusman (3157143), Pamela L. Mellon (3157146), Polly P. Huang (352229), Nicholas J. G. Webster (195220), Anita K. Iyer (3157140)   +4 more
core   +1 more source

Prospective Short‐ and Long‐Term Changes in Cardiometabolic Risk Markers Following Gender‐Affirming Hormone Therapy

Andrology, EarlyView.
ABSTRACT Introduction Gender‐affirming hormone therapy (GAHT) may be associated with increased cardiometabolic disease (CMD) risk. Prospective CMD risk screening is recommended, but long‐term data are needed regarding changes in CMD markers. Objectives To evaluate prospective changes in CMD risk markers during GAHT.
Louise Lehmann Christensen, Camilla Viola Palm, Marianne S. Andersen, Guy T'Sjoen, Jan Frystyk, Tine Taulbjerg Kristensen, Rikke Hjortebjerg, Dorte Glintborg   +7 more
wiley   +1 more source

Binding of WT and R31C GnRH to the GnRH receptor (GnRH-R).

, 2013
(A) COS-7 cells were transiently transfected with a human GnRH-R DNA construct and incubated with a 125I-labeled GnRH agonist in the presence of indicated concentrations of WT GnRH or R31C GnRH. IC-50 values are WT GnRH, 2.8×10−9 M and R31C GnRH, 8.50×10−
Regis Bobe (437214), Marc Lombes (5655703), Philippe Bouchard (212771), Thierry Brue (341760), Megan Gallant (437213), Frederique Albarel (437212), Jerome Bouligand (5652205), Rosario Pivonello (437215), Joelle Cohen-Tannoudji (5655700), Robert P. Millar (304786), Luigi Maione (437211), Jacques Young (101833), Colleen A. Flanagan (287428), Annamaria Colao (437216), Anne Guiochon-Mantel (101841)   +14 more
core   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Uterus histomorphometry of alpacas (Vicugna pacos) in induced luteal phase, with GnRH or Copulation

Open Veterinary Journal
Background: Alpacas have reproductive traits such as induced ovulation and a higher gestation rate in the left uterine horn. Additionally, low fertility and high embryonic mortality are significant challenges in alpaca breeding. To address these issues,
Jose Goicochea-Vargas, Wilson Rondón-Jorge, Fidel Acosta-Pachorro, Max Salvatierra-Alor, Marcelo Ratto-Fuster, Mauricio Silva-Jimenez, Ximena Valderrama-Linares, Roberto Acosta-Galvez, Edson Morales-Parra   +8 more
doaj   +1 more source

Androgen Receptor Expression in Urothelial Bladder Cancer—A Systematic Review and Meta‐Analysis

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Bladder cancer is a globally prevalent malignancy with a marked male predominance. Over the past decade, the androgen receptor has been investigated as a potential contributor to bladder cancer pathophysiology. Androgen receptor expression is most commonly assessed via immunohistochemistry, but its association with pathological ...
Alex Buckby, Mandana Gholami, Matthew Hong, Michael O'Callaghan   +3 more
wiley   +1 more source

Genome‐wide association and interaction analysis for proliferative retinopathy in adults with type 2 diabetes born during famine: The DOLCE study in Ukraine

Acta Ophthalmologica, EarlyView.
Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina, Most Champa Begum, Xuan Tung Trinh, Turkuler Özgumus, Mikael Åkerlund, Peter Nilsson, Leticia Maria Spindola, Valeriya Lyssenko   +7 more
wiley   +1 more source

Veterinarian attitudes towards immunocontraceptive use in cats

Australian Veterinary Journal, EarlyView.
Background The continuously expanding global cat population poses concerns to public health, native ecosystems and individual animal welfare. These concerns have led to additional management strategies to reduce unowned cat numbers, including the development of feline immunocontraceptives.
E Vartola, S Wills, E Cottingham, CD Marth, N Krekeler   +4 more
wiley   +1 more source