PKC‐mediated phosphorylation of FOXL2 weakens DNA binding, alters subnuclear localization and protein interactions, and reshapes FOXL2‐dependent transcriptional programs in granulosa cells, supporting a reversible mechanism that modulates FOXL2 activity through phosphorylation of its DNA‐binding domain. ABSTRACT FOXL2 is a forkhead transcription factor
Ludovic Mousseron +5 more
wiley +1 more source
Microglia Rank signaling regulates GnRH neuronal function and the hypothalamic-pituitary-gonadal axis. [PDF]
Collado-Sole A +25 more
europepmc +1 more source
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu +7 more
wiley +1 more source
Comparison of euploidy rates between progestin-primed ovarian stimulation and GnRH antagonist protocols: a single-center study in a mixed-ethnicity population. [PDF]
Ingold C +3 more
europepmc +1 more source
Semi‐Artificial Breeding Report of Endangered Chitala lopis Using Hormonal Induction Treatments
The graphical abstract of the first successful semi‐artificial breeding of the endangered Giant Featherback (Chitala lopis, Bleeker 1851) by hormonal induction ABSTRACT Reproductive maturity of Chitala lopis is critical for preventing species loss, as the species was previously listed as critically endangered on the IUCN Red List.
Boby Muslimin +18 more
wiley +1 more source
NGF administration is associated with increased GnRH immunoreactivity and a GnRH-associated phenotype in hypothalamic NSCs of aging mice. [PDF]
Luo J +7 more
europepmc +1 more source
Characterization of Lipizzan Horse Population From Lipica Stud Using Molecular and Pedigree Data
ABSTRACT In this study, we analysed genetic diversity, population structure and inbreeding in the Lipica Stud Farm population by integrating pedigree records, microsatellite (STR) and genome‐wide SNP data generated using the GGP Equine 70K BeadChip. The dataset comprised 233 horses from the Lipica Stud Farm, which served as the reference population for
Tamara Ferme +4 more
wiley +1 more source
GnRH Regulates Sex Differentiation in <i>Sebastes schlegelii</i> Through TGF-β/MAPK Signaling Pathways. [PDF]
Huang J, Xu P, Xiao Y, Li J.
europepmc +1 more source
Abstract Background Poor ovarian response (POR) complicates a substantial proportion of in vitro fertilization (IVF) cycles, frequently causing cycle cancellation and suboptimal reproductive outcomes. Conventional follicular‐phase ovarian stimulation (FPOS) protocols often yield limited results, prompting the evaluation of alternative strategies such ...
Vittorio Agrifoglio +8 more
wiley +1 more source
Polymorphism of the Gonadotropin-Releasing Hormone Receptor Gene and Its Association With Production Traits in Isfahani Native Hens. [PDF]
Kheiri F +4 more
europepmc +1 more source

