Results 121 to 130 of about 50,034 (219)

Mechanism and Intervention of the NPY1R/CREB Signaling Axis in Regulating Inflammatory Response in Aged Ovarian Granulosa Cells and Ovarian Senescence

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Aging‐associated upregulation of NPY1R drives p‐CREB activation, triggering inflammation, mitochondrial dysfunction, and extracellular matrix imbalance to promote ovarian senescence. Pharmacological inhibition of NPY1R with BIBO 3304 restores ovarian homeostasis, highlighting a therapeutic strategy for reproductive aging. ABSTRACT Ovarian senescence is
Junnan Fang, Chaoying Wang, Shuaishuai Guo, Yiping Zhang, Yang Zhang, Huihui Wang, Yue Kong, Haixia Jin, Lin Qi, Yan Liu, Zhaoting Wu, Fuli Zhang, Shuang Wen, Xiaopeng Wang, Guang Yang, Guidong Yao   +15 more
wiley   +1 more source

Roles of Goserelin in Gynecological Disorders. [PDF]

Drug Des Devel Ther
Huang X, Gu N, Qian L, Sun F, Yang S, Xu H.   +5 more
europepmc   +1 more source

Prokineticin 2 regulates the electrophysiological activity of gonadotropin-releasing hormone neurons via direct signalling in adult female mice. [PDF]

Front Endocrinol (Lausanne)
Farkas I, Göblyös B, Moi D, Onnis V, Kalló I, Liposits Z.   +5 more
europepmc   +1 more source

PI4-kinase A is essential for survival of the GnRH neurons. [PDF]

Front Endocrinol (Lausanne)
Constantin S, Nessa N, Stojilkovic SS.
europepmc   +1 more source

Impact of GnRH antagonist protocols versus progestin-primed ovarian stimulation on reproductive outcomes in advanced reproductive age women: a propensity score-matched retrospective cohort study. [PDF]

Front Endocrinol (Lausanne)
Qi Z, Wang T, Ren J, Zhao S, Song J, Lian F, Zhao Y.   +6 more
europepmc   +1 more source

Fibroids in obstructed hemivagina and ipsilateral renal anomaly‐like syndrome: Successful hysterectomy and vaginal septoplasty in a kidney transplant recipient with uterus didelphys, vaginal septum and renal agenesis

International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 491-493, July 2026.
Mariana Correia Moreira Cruz, Sophia Helena Batalha, Vitor Matheus Silva, Marcos de Lorenzo Messina, José Maria Soares Junior, Edmund Chada Baracat   +5 more
wiley   +1 more source

Microglia Rank signaling regulates GnRH neuronal function and the hypothalamic-pituitary-gonadal axis. [PDF]

Science
Collado-Sole A, Borjini N, Zhai J, Ruiz-Pino F, Soria-Alcaide G, Folgueira C, García-Vilela C, Romero-de la Rosa B, Lopez V, Zouaghi Y, Jacobs A, Mora-Romero B, Barranco A, Yoldi G, Rizzoti K, Sabio G, Perez-Chacon G, Santamaria PG, Esteban JA, Journiac N, Prevot V, Pascual A, Fernández-Chacón R, Tena-Sempere M, Pitteloud N, Gonzalez-Suarez E.   +25 more
europepmc   +1 more source

Comparison of euploidy rates between progestin-primed ovarian stimulation and GnRH antagonist protocols: a single-center study in a mixed-ethnicity population. [PDF]

Front Endocrinol (Lausanne)
Ingold C, Dos Santos GG, Barbosa CP, De Oliveira R.   +3 more
europepmc   +1 more source

NGF administration is associated with increased GnRH immunoreactivity and a GnRH-associated phenotype in hypothalamic NSCs of aging mice. [PDF]

Front Endocrinol (Lausanne)
Luo J, Jiang J, Zhang T, Zhang X, Huang Y, Zhang X, Wang Y, Yang Y.   +7 more
europepmc   +1 more source

GnRH Regulates Sex Differentiation in <i>Sebastes schlegelii</i> Through TGF-β/MAPK Signaling Pathways. [PDF]

Biology (Basel)
Huang J, Xu P, Xiao Y, Li J.
europepmc   +1 more source