Results 11 to 20 of about 100,933 (268)

GnRH Receptors in Cancer: From Cell Biology to Novel Targeted Therapeutic Strategies [PDF]

Endocrine reviews, 2012
Patrízia Limonta, Marina Montagnani Marelli, Stefania Mai, Marcella Motta, Luciano Martini, Roberta M. Moretti   +5 more
openalex   +2 more sources

GnRH replacement rescues cognition in Down syndrome

Science, 2022
At the present time, no viable treatment exists for cognitive and olfactory deficits in Down syndrome (DS). We show in a DS model (Ts65Dn mice) that these progressive nonreproductive neurological symptoms closely parallel a postpubertal decrease in ...
M. Manfredi-Lozano, Valérie Leysen, M. Adamo, I. Paiva, R. Rovera, J. Pignat, Fatima Ezzahra Timzoura, Michael Candlish, S. Eddarkaoui, S. Malone, M. S. Silva, S. Trova, M. Imbernón, Laurine Decoster, Ludovica Cotellessa, M. Tena-Sempere, M. Claret, A. Paoloni-Giacobino, D. Plassard, Emmanuelle Paccou, N. Vionnet, James Acierno, A. Maceski, A. Lutti, F. Pfrieger, S. Rasika, F. Santoni, U. Boehm, P. Ciofi, L. Buée, N. Haddjeri, A. Boutillier, Jens Kuhle, A. Messina, Bogdan Draganski, P. Giacobini, N. Pitteloud, V. Prévot   +37 more
semanticscholar   +1 more source

Direct evidence that KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Reports suggest that at least 25% of women suffering from reproductive disorders are due to hypothalamic dysfunction. Pulsatile gonadotropin-releasing hormone (GnRH) regimens are used for infertile women.
Mayuko Nagae, Y. Uenoyama, Saki Okamoto, Hitomi Tsuchida, Kana Ikegami, Teppei Goto, S. Majarune, Sho Nakamura, M. Sanbo, M. Hirabayashi, Kenta Kobayashi, Naoko Inoue, H. Tsukamura   +12 more
semanticscholar   +1 more source

Estrus synchronization protocols for fixed-time artificial insemination (FTAI) during non-breeding season in ewes [PDF]

Journal of Central European Agriculture
This study aimed to compare three protocols used for induction and estrus synchronization followed by fixed-time artificial insemination (FTAI) during the non-breeding season in anestrous Cluj Merino ewes.
Alexandru DEAC, Doru POP, Marius AIPĂTIOAIE, Adriana MUSCĂ, Ștefania MESEȘAN, Ileana MICLEA, Ioan LADOȘI, Marius ZĂHAN   +7 more
doaj   +1 more source

Comparisons of GnRH Antagonist versus GnRH Agonist Protocol in Supposed Normal Ovarian Responders Undergoing IVF: A Systematic Review and Meta-Analysis

PLoS ONE, 2014
Objective To evaluate the effectiveness and safety of GnRH antagonist and GnRH agonist in supposed normal ovarian responders undergoing IVF. Methods Data from 6 databases were retrieved for this study.
Jinsong Xiao, Cunmei Su, Xian‐Tao Zeng
openalex   +3 more sources

Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion

Nature Communications, 2016
Anti-Müllerian hormone (AMH) plays crucial roles in sexual differentiation and gonadal functions. However, the possible extragonadal effects of AMH on the hypothalamic–pituitary–gonadal axis remain unexplored.
I. Cimino, F. Casoni, Xinhuai Liu, A. Messina, J. Parkash, Soazik P. Jamin, S. Catteau-jonard, F. Collier, M. Baroncini, D. Dewailly, P. Pigny, Melanie Prescott, R. Campbell, A. Herbison, V. Prévot, P. Giacobini   +15 more
semanticscholar   +1 more source

Pengaruh Pemberian Gonadotropin Releasing Hormone (GnRH) Terhadap Peningkatan Kualitas Spermatozoa Sapi Bali Pengaruh Pemberian Gonadotropin Releasing Hormone (GnRH) Terhadap Peningkatan Kualitas Spermatozoa Sapi Bali

Jurnal Sain Veteriner, 2022
Penelitian ini bertujuan mengetahui pengaruh pemberian gonadotropin releasing hormone (GnRH) terhadap peningkatan kualitas spermatozoa sapi bali. Penelitian ini menggunakan dua ekor sapi bali berumur 2 dan 4 tahun dengan rancangan pola bujursangkar latin
Amalia Sutriana, Tongku Nizwan Siregar, Feby Claudia Sirait, Juli Melia, Hafizuddin .   +4 more
doaj   +1 more source

GnRH dysregulation in polycystic ovarian syndrome (PCOS) is a manifestation of an altered neurotransmitter profile

Reproductive Biology and Endocrinology, 2018
BackgroundGnRH is the master molecule of reproduction that is influenced by several intrinsic and extrinsic factors such as neurotransmitters and neuropeptides.
Nirja Chaudhari, Mitali Dawalbhakta, L. Nampoothiri   +2 more
semanticscholar   +1 more source

COMPARATIVE STUDY OF USE SOMETREATMENTAL REGIMES TOTREAT POSTPARTUM FUNCTIONAL INFERTILITY OF COWS IN BASRA [PDF]

Basrah Journal of Veterinary Research, 2019
Postpartum an estrus in cows is regarded as one of the most important causes of functional infertility after parturition during reproductive lifespan. Therefor the present study was conducted to induce fertile estrus in anestrus cows which suffered from ...
doaj   +1 more source

Nasal Placode Development, GnRH Neuronal Migration and Kallmann Syndrome

Front. Cell Dev. Biol., 2019
The development of Gonadotropin releasing hormone-1 (GnRH) neurons is important for a functional reproduction system in vertebrates. Disruption of GnRH results in hypogonadism and if accompanied by anosmia is termed Kallmann Syndrome (KS).
Hyun‐Ju Cho, Y. Shan, Niteace C. Whittington, S. Wray   +3 more
semanticscholar   +1 more source