Results 101 to 110 of about 194,150 (247)

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

GnRH-II agonist [D-Lys(6)]GnRH-II inhibits the EGF-induced mitogenic signal transduction in human endometrial and ovarian cancer cells

, 2006
The majority of human endometrial and ovarian cancers express receptors for GnRH type I (GnRH-I). Their proliferation is time- and dose-dependently reduced by GnRH-I and its analogs. GnRH-I analogs activate a phosphotyrosine-phosphatase (PTP) and inhibit
Eicke, Nicola, Guenthert, Andreas R., Emons, Guenter, Gruendker, Carsten   +3 more
core   +1 more source

Postlaparoscopic GnRHagonist Therapy does not Improve Spontaneous Conception Rates of Women with Endometriosis

Indonesian Journal of Obstetrics and Gynecology, 2017
Objective: To investigate the reproductive benefits of combining laparoscopic surgery with GnRH-agonist hormonal therapy in treating women with endometriosis.
Kevin D Tjandraprawira, Tono Djuwantono
doaj   +1 more source

Persistent Pelvic Adhesions and Fibrotic Remodeling Following Ectopic Lesion Ablation in a Mouse Model of Endometriosis

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
DT‐mediated ablation eliminated detectable donor‐derived ectopic lesions. However, pelvic adhesions, collagen‐rich fibrosis, α‐SMA‐positive fibrotic remodeling, and functional behavioral alterations persisted. These findings indicate that lesion ablation alone is insufficient to resolve established adhesion‐associated fibrotic remodeling and identify ...
Sohyeon Yun, Kyeong A. So, Eunhee M. Jeong, Marissa G. Hoover, Abu Raihan, Lisa Brennaman, Jung‐Yoon Yoo, Andrew M. Kelleher, Tae Hoon Kim, Jung‐Ho Shin, Jae‐Wook Jeong   +10 more
wiley   +1 more source

Estrogen Receptor Beta Isoforms Interplay Integrates Nuclear and Extra‐Nuclear Signaling to Modulate Human Granulosa Cell Growth

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
Working model of ERβ isoform signaling in human granulosa cells. Upon E2 binding, ERβ1 activates ERE‐dependent transcription and represses AP‐1 activity through Jun/Fos interactions. In contrast, ERβ2, ERβ4, and ERβ5 lack E2 binding and ERE activity but promote AP‐1‐dependent transcription and counteract ERβ1 repression, including after phosphorylation
Clémentine Marie, Inza‐Noor Baskaran, Raphaël Corre, Anne Mayeur, Michaël Grynberg, Guillaume Chevreux, David L'Hôte, Joëlle Cohen‐Tannoudji, Stéphanie Chauvin   +8 more
wiley   +1 more source

Graves' Disease Associated with Goserelin Acetate [PDF]

, 2002
We describe a case of Graves' disease associated with goserelin acetate. A 47-year-old woman experienced thyrotoxicosis during the administration of goserelin acetate, a gonadotropin-releasing hormone (GnRH) -agonist.
Ueda, Yasuo, Morita, Shigeki
core  

Antitumor effect of GnRH agonist in epithelial overian cancer

, 1999
Objective. The effects of the gonadotropin releasing hormone (GnRH) agonist (D-Trp6) were examined in two human ovarian cancer cell lines and in severe combined immune deficiency (SCID) mice to evaluate its potential as a cytocidal, cytostatic, or ...
Jae Keun Jung, Dae Hoon Kim, Young Ae Lim, Dong Choon Park, Young Ok Lew, Yang Kyu Choi, Sung Eun Namkoong, Jin Woo Kim, Jae Hoon Kim   +8 more
core   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Coexisting adenomyosis in endometriosis: Similar pain and quality of life, with longer bleeding and bowel symptoms—A comparative cross‐sectional study

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 164-173, October 2026.
Abstract Objective To compare pain, menstrual flow, and quality of life (QoL) between women undergoing surgery for endometriosis only compared with women with endometriosis and coexisting adenomyosis. Methods A cross‐sectional study, set in two tertiary hospitals, of reproductive‐aged women (18–50 years) with a preoperative imaging diagnosis of ...
Mariana Matzenbacher Brunoro, Ana Clara Pimenta Servidoni, Sofia Di Nur Wakabayashi, Camila Rebeque Dagola, Marina Paula Andres, Mauricio Simoes Abrao   +5 more
wiley   +1 more source

A comparative study on oxidative and antioxidative markers of serum and follicular fluid in GnRH agonist and antagonist cycles

, 2012
To determine whether concentrations of oxidative stress markers of follicular fluid and serum are different in GnRH agonist protocol from GnRH antagonist ...
TÜRKÇÜOĞLU, ILGIN, ÖZEROL, ELİF, Celik, Ebru, Simsek, Yavuz, KARAER, ABDULLAH, Minareci, Yağmur, TANBEK, KEVSER, Kumbak, Banu, YILMAZ, ERCAN, Celik, Onder   +9 more
core   +1 more source