Results 81 to 90 of about 425,428 (324)

Contributions of the ventromedial prefrontal cortex to goal-directed action selection [PDF]

, 2011
In this article, it will be argued that one of the key contributions of the ventromedial prefrontal cortex (vmPFC) to goal-directed action selection lies both in retrieving the value of goals that are the putative outcomes of the decision process and in ...
O'Doherty, John P.
core  

A Goal-Directed Implementation of Query Answering for Hybrid MKNF Knowledge Bases

, 2012
Ontologies and rules are usually loosely coupled in knowledge representation formalisms. In fact, ontologies use open-world reasoning while the leading semantics for rules use non-monotonic, closed-world reasoning.
ANA SOFIA GOMES, Baral, Drabent, Eiter, Gelfond, Hitzler, Horrocks, JOSÉ JÚLIO ALFERES, Knorr, Lifschitz, Lukacsy, Motik, Patel, Swift, TERRANCE SWIFT, van Gelder, Yang   +16 more
core   +1 more source

Influence on Habitual versus Goal-Directed Decision Making [PDF]

, 2016
Different systems for habitual versus goal-directed control are thought to underlie human decision-making. Working memory is known to shape these decision-making systems and their interplay, and is known to support goal- directed decision making even ...
Heinz, Andreas, Kuschpel, Maxim S., Liu, Shuyan, Rapp, Michael A., Schad, Daniel J.   +4 more
core   +1 more source

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

Molecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns, Ulrik Ringborg, Julio Celis, Bengt Jönsson, Michael Baumann   +4 more
wiley   +1 more source

Tactile suppression in goal-directed movement [PDF]

Psychonomic Bulletin & Review, 2016
Sharing numerous characteristics with suppression in the other senses, tactile suppression is a reliable phenomenon that accompanies movement. By investigating the simplest of movements (e.g., finger flexions), early research tried to explain the origins of the phenomenon in terms of motor command generation together with sensory reafference.
Juravle, G, Binstead, G, Spence, C
openaire   +4 more sources

Neuroimaging of Habit-based vs. Goal-directed behavior in Instrumental Learning [PDF]

, 2017
Addiction has been proposed to result from an overreliance on the habit-based and goal-directed controllers of behavior; however, few data exist to simultaneously support both behavioral and neuoranatomical aspects of this theory in humans.
Lawler, Michael Jacob
core   +1 more source

Goal-Directed Treatment for Osteoporosis: A Progress Report from the ASBMR-NOF Working Group on Goal-Directed Treatment for Osteoporosis. [PDF]

, 2017
The American Society for Bone and Mineral Research and the United States National Osteoporosis Foundation (NOF) formed a working group to develop principles of goal-directed treatment and identify gaps that need to be filled to implement this approach ...
Adler, Austin, Black, Black, Black, Black, Boonen, Brown, Center, Clinton, Cosman, Cosman, Cosman, Cosman, Cosman, Crandall, Cummings, Cummings, Diez-Perez, Diez-Perez, Ferrari, Fink, Freemantle, Giangregorio, Hadji, Hochberg, Johnell, Kanis, Kanis, Leder, Leslie, Leslie, Lewiecki, Lewiecki, Lindsay, Marshall, McClung, McClure, Murad, Neuner, Recknor, Ryg, Schousboe, Schousboe, Schwartz, Shepherd, Siminoski, Siris, Siris, van Geel, Wasnich, Watts   +51 more
core   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

FEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Impaired goal-directed behavioural control in human impulsivity. [PDF]

, 2017
PublishedJournal ArticleResearch Support, Non-U.S. Gov'tThis is the final version of the article. Available from Taylor & Francis (Routledge) via the DOI in this record.Two dissociable learning processes underlie instrumental behaviour.
Baess, K, Chase, HW, Hogarth, L
core   +1 more source