Results 61 to 70 of about 3,565,746 (293)
Communication for Goal Directed Agents
, 2003 This paper discusses some modeling issues concerning the communication between goal-directed agents. In particular, the role of performatives in agent communication is discussed. It is argued that the specification of the effect of performatives, as prescribed by FIPA, is sometimes too weak or unrealistic.
Mehdi Dastani +2 more
openaire +4 more sources
A Goal-Directed Bayesian Framework for Categorization [PDF]
Frontiers in Psychology, 2017 Categorization is a fundamental ability for efficient behavioral control. It allows organisms to remember the correct responses to categorical cues and not for every stimulus encountered (hence eluding computational cost or complexity), and to generalize appropriate responses to novel stimuli dependant on category assignment.
Rigoli, F. +3 more
openaire +6 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Should we use early less invasive hemodynamic monitoring in unstable ICU patients? [PDF]
, 2011 In the previous issue of Critical Care, Takala and colleagues presented the results of a multicenter study to investigate whether the early presence of less invasive hemodynamic monitoring improves outcome in patients admitted with hemodynamic ...
Maurizio Cecconi +3 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Discrepancy between goal-directed learning and habit.
, 2023 Discrepancy between goal-directed learning and habit.
Alexey Kuznetsov (435093) +2 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Frontiers in Pediatrics, 2023 ObjectiveTo investigate the effectiveness of hip continuous passive motion (hCPM) on hip development at skeletal maturity and gross motor function for spastic cerebral palsy children with hip dysplasia.MethodsProspective case–control research of hCPM ...
Lulu Wang +8 more
doaj +1 more source
Noise characteristics for goal-directed reaching simulations.
, 2022 Noise characteristics for goal-directed reaching simulations.
Friedl De Groote (2542747) +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source