Results 71 to 80 of about 7,767,661 (277)

Goal-directed colloid administration improves the microcirculation of healthy and perianastomotic colon

, 2009
BACKGROUND: The aim of this study was to compare the effects of goal-directed colloid fluid therapy with goal-directed crystalloid and restricted crystalloid fluid therapy on healthy and perianastomotic colon tissue in a pig model of colon anastomosis ...
Hiltebrand, Luzius, Kimberger, Oliver, Arnberger, Michael, Brandt, Sebastian, Plock, Jan, Kurz, Andrea, Sigurdsson, Gisli H, Kimberger O, Plock J, Kurz A, Arnberger M, Brandt S, Sigurdsson GH, Hiltebrand L, Plock, Jan Alexander   +14 more
core   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

Qualitative exploration of a client-centred, goal-directed approach to community-based occupational therapy for adults with traumatic brain injury

, 2009
OBJECTIVES. We explored the clinical application of goal-directed therapy in community-based rehabilitation from the perspective of clients with traumatic brain injury (TBI), their significant others, and their treating occupational therapists.
Doig, Emmah, Jennifer Fleming, Cornwell, Petrea L., Cornwell, Petrea L, Petrea L. Cornwell, Emmah Doig, Kuipers, Pim, Fleming, Jennifer, Pim Kuipers   +8 more
core   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Clinical and economic impact of goal-directed fluid therapy during elective gastrointestinal surgery

Perioperative Medicine, 2018
Background Several randomized controlled trials suggest that goal-directed fluid therapy (GDFT) may result in improved postoperative outcomes. The aim of this study was to assess the clinical and financial impact of the real-life implementation of ...
Juying Jin, Su Min, Dan Liu, Ling Liu, Bixiao Lv   +4 more
doaj   +1 more source

Perioperative Quality Initiative (POQI) consensus statement on fundamental concepts in perioperative fluid management: fluid responsiveness and venous capacitance

Perioperative Medicine, 2020
Background Optimal fluid therapy in the perioperative and critical care settings depends on understanding the underlying cardiovascular physiology and individualizing assessment of the dynamic patient state.
Greg S. Martin, David A. Kaufman, Paul E. Marik, Nathan I. Shapiro, Denny Z. H. Levett, John Whittle, David B. MacLeod, Desiree Chappell, Jonathan Lacey, Tom Woodcock, Kay Mitchell, Manu L. N. G. Malbrain, Tom M. Woodcock, Daniel Martin, Chris H. E. Imray, Michael W. Manning, Henry Howe, Michael P. W. Grocott, Monty G. Mythen, Tong J. Gan, Timothy E. Miller   +20 more
doaj   +1 more source

The impact of intraoperative goal-directed fluid therapy on complications after pancreaticoduodenectomy

Annals of Medicine and Surgery, 2018
Optimal fluid balance is critical to minimize anastomotic edema in patients undergoing pancreaticoduodenectomy. We examined the effects of decreased fluid administration on rates of postoperative pancreatic leak and delayed gastric emptying.Retrospective study of 105 patients undergoing pancreaticoduodenectomy at a single institution from January 2015 ...
Jesse K. Sulzer, Amit V. Sastry, Lauren M. Meyer, Allyson Cochran, William C. Buhrman, Erin H. Baker, John B. Martinie, David A. Iannitti, Dionisios Vrochides   +8 more
openaire   +2 more sources

A Critical Call for Mechanistic Investigations of Metal‐Bacteria Interactions

Advanced Materials, EarlyView.
It is well established that the antibacterial properties of metals have tremendous importance for bioengineering applications. What is not as appreciated, however, is the reproducibility crisis in this field's vast literature. In this perspective, we highlight this reproducibility problem, discuss its sources, and suggest solutions towards focused ...
J. Rackwitz, A. Bandyopadhyay, S. Belkin, S. Bose, N. Eliaz, J. L. Gilbert, T. C. Lowe, F. Mücklich, R. J. Turner, C. C. Tasan   +9 more
wiley   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Barriers to the Use of Goal Directed Therapy in a High Risk Surgical Patient Group [PDF]

, 2019
PhDBackground Goal directed therapy, the utilisation of fluids and inotropes to optimise cardiovascular performance of tissue oxygen delivery during surgery, has been shown in small studies to reduce complications after major surgery.
Macdonald, N
core   +4 more sources