Results 161 to 170 of about 200,215 (293)

Quality of care for people with mental handicap and challenging behaviour : an investigation of the impact of staff training in goal attainment scaling and behavioural procedures

, 2012
This study examined the contribution to quality of care of a goal planning technique called Goal Attainment Scaling and its impact upon the quality of life of people with severe mental handicaps and challenging behaviour.
Turnbull, John
core  

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Efficacy of early goal-directed therapy for hemodynamics stability in off-pump coronary artery bypass surgery. [PDF]

Sci Rep
Khanh BQ, Dung NC, Van Viet P, Doan BC, Thanh BD, Hoa BT, Son PT, Pho DC.   +7 more
europepmc   +1 more source

Feasibility and beneficial effects of an early goal directed therapy after cardiac arrest: evaluation by conductance method. [PDF]

Sci Rep, 2021
Broch O, Hummitzsch L, Renner J, Meybohm P, Albrecht M, Rosenthal P, Rosenthal AC, Steinfath M, Bein B, Gruenewald M.   +9 more
europepmc   +1 more source

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

Advanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan, Hongming Li, Camille Blaine, Julie Grier, Ethan Hammett, Almaris Figueroa‐Gonzalez, Sarai Garcia, Romain Duprat, Justin Reber, Joseph Deluisi, Christos Davatzikos, Theodore D. Satterthwaite, Yong Fan, Desmond J. Oathes   +13 more
wiley   +1 more source

Continuous Hemodynamic Monitoring and Goal-Directed Therapy for Optimization in Total Knee Replacement: A Prospective Observational Study. [PDF]

Cureus
Christofis C, Kyriakou M, Arvanitaki A, Tilkeridis K, Kazakos K, Vogiatzaki T, Pelagia C.   +6 more
europepmc   +1 more source

Resuscitation of patients with septic shock: please "mind the gap"! [PDF]

, 2013
Pinsky, MR, Vallet, B, B. Vallet, M. R. Pinsky, M. Cecconi, Cecconi, M   +5 more
core   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

Comparison of Hemodynamic Management by Hypotension Prediction Index or Goal-Directed Therapy in Radical Cystectomies: A Prospective Observational Study. [PDF]

J Clin Med
Brusasco C, Micali M, Cucciolini G, Filolli D, Gandini M, Lattuada M, Introini C, Corradi F.   +7 more
europepmc   +1 more source

Efficacy of early goal-directed therapy using FloTrac/EV1000 to improve postoperative outcomes in patients undergoing off-pump coronary artery bypass surgery: a randomized controlled trial. [PDF]

J Cardiothorac Surg, 2022
Tribuddharat S, Sathitkarnmanee T, Ngamsaengsirisup K, Sornpirom S.   +3 more
europepmc   +1 more source