Feasibility and beneficial effects of an early goal directed therapy after cardiac arrest: evaluation by conductance method. [PDF]
Broch O +9 more
europepmc +1 more source
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan +6 more
wiley +1 more source
Continuous Hemodynamic Monitoring and Goal-Directed Therapy for Optimization in Total Knee Replacement: A Prospective Observational Study. [PDF]
Christofis C +6 more
europepmc +1 more source
Impact of Goal Directed Therapy in Head and Neck Oncological Surgery with Microsurgical Reconstruction: Free Flap Viability and Complications. [PDF]
Tapia B +6 more
europepmc +1 more source
Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai +18 more
wiley +1 more source
Comparison of Hemodynamic Management by Hypotension Prediction Index or Goal-Directed Therapy in Radical Cystectomies: A Prospective Observational Study. [PDF]
Brusasco C +7 more
europepmc +1 more source
Efficacy of early goal-directed therapy using FloTrac/EV1000 to improve postoperative outcomes in patients undergoing off-pump coronary artery bypass surgery: a randomized controlled trial. [PDF]
Tribuddharat S +3 more
europepmc +1 more source
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang +19 more
wiley +1 more source
Perioperative predictors of complications in open abdominal aortic surgery: A retrospective analysis under a structured perioperative goal-directed therapy protocol. [PDF]
De Rosa RC, Romanelli A.
europepmc +1 more source
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li +9 more
wiley +1 more source

