Maladaptive behavior and affect regulation: A functionalist perspective. [PDF]
Clinical science has benefited tremendously from taking seriously the proposition that putatively maladaptive behaviors serve psychological functions, prominently among these affect regulation (AR).
Johnson, Sheri L +4 more
core
Weekly assessment of worry: an adaptation of the Penn State Worry Questionnaire for monitoring changes during treatment [PDF]
An adaptation of the Penn State Worry Questionnaire (PSWQ) [Meyer, T. J., Miller, M. L., Metzger, R. L. and Borkovec, T. D. (1990). Development and validation of the Penn State Worry Questionnaire. Behaviour Research and Therapy, 28, 487-495.] for weekly
Beck +16 more
core +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Goal-directed fluid therapy optimizes hemodynamics on the elderly patients undergoing lumbar decompressive surgery and reduces postoperative complications [PDF]
Objective To explore the impact of goal-directed fluid therapy(GDT) management strategy on the perioperative complications of elderly patients undergoing lumbar spine surgery.
XIA Di, XU Li, LI Xu, HUANG Yu-guang
doaj
A randomized, single-blind cross-over design evaluating the effectiveness of an individually defined, targeted physical therapy approach in treatment of children with cerebral palsy [PDF]
Objective: A pilot study to compare the effectiveness of an individual therapy program with the effects of a general physical therapy program. Design: A randomized, single-blind cross-over design.
De Cat, Josse +6 more
core +2 more sources
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
New progress of goal-directed fluid therapy in enhanced recovery after surgery [PDF]
Goal-directed fluid therapy(GDFT) is an important method to accelerate patients rehabilitation after surgical operation. It can maintain the stability of hemodynamic indexes, balance of oxygen supply and demand, reduce the perioperative inflammatory ...
HE Xiao-yi, ZOU Xue-jun, XING Hao-ran
doaj
First-line therapy in HER2 positive metastatic breast cancer. Is the mosaic fully completed or are we missing additional pieces? [PDF]
The discovery of human epidermal growth factor receptor 2 (HER2) and its role in the biology of breast cancer and the subsequent development of HER2-targeted therapies, have dramatically improved clinical outcomes for women with early-stage and advanced ...
Cognetti F. +3 more
core +2 more sources
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Early goal-directed therapy: a UK perspective [PDF]
The surviving sepsis campaign developed guidelines in 2003 that were designed to increase physician awareness of sepsis and to develop a series of recommendations for the management of the patient with sepsis. The guidelines had the support of 11 international professional organisations across a variety of specialties, and advocate aggressive, early ...
A D, Reuben +4 more
openaire +2 more sources

