Results 91 to 100 of about 2,211,967 (315)
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
A remote sensing-based method for river discharge estimation in data-scarce regions
River discharge is a key hydrological parameter essential for understanding the water cycle, managing water resources, and assessing the impacts of climate change.
Yuan Guo +8 more
doaj +1 more source
Goals for teaching: Towards a framework for examining motivation of graduating teachers [PDF]
Teacher motivation is an important field of research, especially in countries where teacher retention and quality have become prominent concerns. This paper presents a conceptual framework for understanding the stage appropriate goals for teaching of ...
Mansfield, C. +5 more
core +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Accuracy assessment is an indispensable part of land cover change monitoring, the core of which is obtaining high-quality validation datasets. This study proposes a novel and online interactive toolkit (Visual Interpretation Toolkit) for collecting ...
Tingting Zhao, Xiao Zhang, Liangyun Liu
doaj +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Effect of goal activation on goal management
Studies of goal management have examined how to manage multiple goals. Previous research (Finkelstein & Fislibach, 2010) showed that healthy eating made one hungrier. This study hypothesized that participants were hungrier when a health goal was not activated than when it was activated.
openaire +3 more sources
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source

