Results 91 to 100 of about 2,211,967 (315)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

A remote sensing-based method for river discharge estimation in data-scarce regions

open access: yesInternational Journal of Digital Earth
River discharge is a key hydrological parameter essential for understanding the water cycle, managing water resources, and assessing the impacts of climate change.
Yuan Guo   +8 more
doaj   +1 more source

Goals for teaching: Towards a framework for examining motivation of graduating teachers [PDF]

open access: yes, 2012
Teacher motivation is an important field of research, especially in countries where teacher retention and quality have become prominent concerns. This paper presents a conceptual framework for understanding the stage appropriate goals for teaching of ...
Mansfield, C.   +5 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

An interactive toolkit based on Google Earth Engine for visual interpretation and analysis of land cover and land cover changes

open access: yesBig Earth Data
Accuracy assessment is an indispensable part of land cover change monitoring, the core of which is obtaining high-quality validation datasets. This study proposes a novel and online interactive toolkit (Visual Interpretation Toolkit) for collecting ...
Tingting Zhao, Xiao Zhang, Liangyun Liu
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Effect of goal activation on goal management

open access: yesThe Japanese journal of psychology, 2015
Studies of goal management have examined how to manage multiple goals. Previous research (Finkelstein & Fislibach, 2010) showed that healthy eating made one hungrier. This study hypothesized that participants were hungrier when a health goal was not activated than when it was activated.
openaire   +3 more sources

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Goals for Memphis - 1997 Annual Report

open access: yes, 1998
1997 Annual Report of the "Goals for Memphis ...

core  

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