Results 71 to 80 of about 2,211,967 (315)

U.S. President Barack Obama speaks at the Millennium Development Goals conference

, 2010
President Obama speaks at the Millennium Development Goals conference at the United Nations building. Obama reemphasizes UN goals which include eradicating extreme poverty, reducing child mortality rates, fighting disease, and developing a global ...
Obama, Barack
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

SPT-UNet: A Superpixel-Level Feature Fusion Network for Water Extraction from SAR Imagery

Remote Sensing
Extracting water bodies from synthetic aperture radar (SAR) images plays a crucial role in the management of water resources, flood monitoring, and other applications.
Teng Zhao, Xiaoping Du, Chen Xu, Hongdeng Jian, Zhipeng Pei, Junjie Zhu, Zhenzhen Yan, Xiangtao Fan   +7 more
doaj   +1 more source

A new denoising method for photon-counting LiDAR data with different surface types and observation conditions

International Journal of Digital Earth, 2023
Spaceborne photon-counting LiDAR is significantly affected by noise, and existing denoising algorithms cannot be universally adapted to different surface types and topographies under all observation conditions.
Jieying Lao, Cheng Wang, Sheng Nie, Xiaohuan Xi, Hui Long, Baokun Feng, Zijia Wang   +6 more
doaj   +1 more source

Do Goals Matter in Engineering Education? An Exploration of How Goals Influence Outcomes for FIRST Robotics Participants [PDF]

, 2012
It has long been recognized that engineers need a variety of skills, including technical and social, to succeed professionally. Attempts to include social skills (i.e., communication, teamwork, and leadership) in engineering education are relatively ...
Skorinko, Jeanine L., Doyle, James K., Tryggvason, Gretar   +2 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Financing the Millennium Development Goals for health and beyond: sustaining the 'Big Push'. [PDF]

, 2010
Many of the Millennium Development Goals are not being achieved in the world's poorest countries, yet only five years remain until the target date. The financing of these Goals is not merely insufficient; current evidence indicates that the temporary ...
McKee, M., David Stuckler, McKee, Martin, Basu, Sanjay, Gorik Ooms, Ooms, G., Sanjay Basu, Stuckler, David, Basu, S., Martin McKee, Ooms, Gorik, Stuckler, D.   +11 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Inconsistent Diurnal Patterns of Far-Red Solar-Induced Chlorophyll Fluorescence Retrieved with Different Algorithms from Tower-Based Observations

Journal of Remote Sensing
Tower-based solar-induced chlorophyll fluorescence (SIF) measurements have yielded crucial datasets for investigating the diurnal patterns of SIF and its relationship with vegetation photosynthesis.
Xinjie Liu, Liangyun Liu, Shanshan Du, Mengjia Qi   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source