Results 61 to 70 of about 2,281,943 (313)
A Review of Research on the Stability of Fine-Grained Sediments in Debris Flows
GeosciencesFine-grained sediments in debris flows refer to Quaternary sediments with grain sizes smaller than 2 mm. Their stability is closely related to the initial water threshold that triggers the debris flows and thus controls the density, scale, and damage of ...
Qinjun Wang +4 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
International Journal of Digital Earth, 2023 Spaceborne photon-counting LiDAR is significantly affected by noise, and existing denoising algorithms cannot be universally adapted to different surface types and topographies under all observation conditions.
Jieying Lao +6 more
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Goals for teaching: Towards a framework for examining motivation of graduating teachers [PDF]
, 2012 Teacher motivation is an important field of research, especially in countries where teacher retention and quality have become prominent concerns. This paper presents a conceptual framework for understanding the stage appropriate goals for teaching of ...
Mansfield, C. +5 more
core +1 more source
Computational Intelligence Methodologies Applied to Sustainable Development Goals
, 2022 This book presents computational intelligence methodologies and its applications to sustainable development goals. Along 18 chapters prepared by reputed scientists around the world, this book explores and focuses on the impacts produced by the ...
Brito Santana, Julio +2 more
core +1 more source
SPT-UNet: A Superpixel-Level Feature Fusion Network for Water Extraction from SAR Imagery
Remote SensingExtracting water bodies from synthetic aperture radar (SAR) images plays a crucial role in the management of water resources, flood monitoring, and other applications.
Teng Zhao +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source