Results 61 to 70 of about 2,211,967 (315)

A systematic study of interactions between sustainable development goals (SDGs) in Hainan Island

open access: yesScientific Reports
The 2030 Agenda for Sustainable Development issued by the United Nations is an important foundation for countries to achieve common economic, social and environmental development.
Linyan Bai   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Spatial Population Distribution Data Disaggregation Based on SDGSAT-1 Nighttime Light and Land Use Data Using Guilin, China, as an Example

open access: yesRemote Sensing, 2023
A high-resolution population distribution map is crucial for numerous applications such as urban planning, disaster management, public health, and resource allocation, and it plays a pivotal role in evaluating and making decisions to achieve the UN ...
Can Liu   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Review of Research on the Stability of Fine-Grained Sediments in Debris Flows

open access: yesGeosciences
Fine-grained sediments in debris flows refer to Quaternary sediments with grain sizes smaller than 2 mm. Their stability is closely related to the initial water threshold that triggers the debris flows and thus controls the density, scale, and damage of ...
Qinjun Wang   +4 more
doaj   +1 more source

Social Goals

open access: yes, 2019
The history of social goals began decades ago in the psychological literature. Over time, several different goal paradigms emerged building from drive theory, goal approach, and self-determination theory. This chapter discusses the historical origins and
McInerney, Dennis M.   +3 more
core   +1 more source

Effects of communication goals and expectancies on language abstraction. [PDF]

open access: yes, 2003
Language abstraction is an important aspect of the description of behavioral events (G.R. Semin & K. Fiedler, 1988) that is typically viewed as a medium by which describers transmit beliefs without conscious awareness or control.
Douglas, Karen, Sutton, Robbie M.
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Academic and social goals in adolescence: developments and directions. [PDF]

open access: yes, 2007
Over the past fifteen years there has been an increased research interest in motivation in learning contexts. Research in the field has been lead by those working with motivational goal theory, which emphasises the reasons students engage in achievement ...
Mansfield, C.
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy