Results 141 to 150 of about 2,502,296 (297)

Evaluation of the Safety and Immunogenicity of a Peste Des Petits Ruminants (PPR), Sheep and Goat Pox (SGP) and Contagious Caprine Pleuropneumonia (CCPP) Multivalent Vaccine (JOVAC-Combo^®) Under Field Conditions in Somalia. [PDF]

Viruses
Almajali AM, Shawash H, Salaita H, Mahapatra M, Parida S, Wilson S.   +5 more
europepmc   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Migratory Sheep and Goat Production System: The Mainstay of Tribal Hill Economy in Himachal Pradesh [PDF]

The migratory and socio-economic aspects of sheep and goat flock-owners have been studied to examine yield, cost, income and employment in migratory sheep and goat production system in the Kangra district of Himachal Pradesh for the year 2001-02.
Singh, D.R., Kaul, Sushila, Sivaramane, N.   +2 more
core  

Goat productivity under smallholder farmer management in semi-arid and hot-humid parts of Zimbabwe: a useful step for building resilient goat production systems in marginalized communities. [PDF]

Trop Anim Health Prod
Munengwa A, Nyahangare ET, Jambwa P, Mugoti A, Mandara S, Dzviti M, Chikumba N, McGaw LJ.   +7 more
europepmc   +1 more source

Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection

Advanced Science, EarlyView.
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse, Sixtine Coindre, Anne Wijkhuisen, Romain Marlin, Laure Fournier Le Ray, Juliette Pons, Melyssa Yaugel‐Novoa, Véronique Avettand‐Fenoel, Laurent Abi‐Rached, Anne‐Sophie Gallouet, Francis Relouzat, Mael Gourves, Asier Saez‐Cirion, Hisashi Arase, Gerard Zurawski, Sandra Zurawski, Nathalie Dereuddre‐Bosquet, Roger Le Grand, Stéphanie Simon, Olivier Lambotte, Benoit Favier   +20 more
wiley   +1 more source

Olfactory neuroblastoma in a goat. [PDF]

Vet Res Commun
Mascaro SB, Suárez-Bonnet A, Dunkel B, Jeckel S, Martí-Garcia B.   +4 more
europepmc   +1 more source

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

Advanced Science, EarlyView.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shang   +9 more
wiley   +1 more source

Diversity and Occurrence of Tick-Borne Pathogens in Small Ruminants and Their Ticks in Sardinia: Implications for Animal Health and Zoonotic Risk. [PDF]

Vet Sci
Chisu V, Zobba R, Giua L, Foxi C, Bianco P, Chessa G, Masala G, Alberti A, Cabras P.   +8 more
europepmc   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

High Seropositivity to <i>Coxiella burnetii</i> Among Goats Sampled in Southwestern Jeonnam Province, South Korea: A Pilot Study. [PDF]

Animals (Basel)
Bok EY, Kwak CR, Lee HG, Kim D, Lee ED, Kim KW, Cho A, Jung Y, Kang SJ, Jung BG.   +9 more
europepmc   +1 more source