Results 51 to 60 of about 69,761 (267)

Understanding the skin blackening phenomenon in Youzhou Dark goats based on the histological characteristics of melanocytes

Journal of Advanced Veterinary and Animal Research
Objective: The study was conducted to identify the molecular mechanism of the phenotype formation of Youzhou black sheep by histological cytology and transcriptomics.
Cancan Chen, Jie Li, Xiaoyan Sun, Jing Jiang, Shipeng Lv, Liangjia Liu, Gaofu Wang, Hangxing Ren   +7 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Role of certain growth factors and hormones in folliculogenesis

Indian Journal of Animal Sciences, 2020
Folliculogenesis is an inextricable process associated with female fertility and infertility cases. This process involves many events at cellular and molecular level in a highly orchestrated fashion which culminates with ovulation.
SURESH DINKAR KHARCHE, DAYANIDHI JENA, CHETNA GANGWAR, AMIT KHATTI, B BALAMURUGAN   +4 more
doaj   +1 more source

On the angora goat

Papers and proceedings of the Royal Society of Tasmania, 1874
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Exogenous catalase improves the goat seminal attributes at refrigeration temperature

Indian Journal of Animal Sciences, 2020
The objective of the present study was to evaluate the potential benefit of catalase (CAT) on sperm functional parameters (motility, viability, membrane integrity and acrosomal integrity) during liquid storage of buck spermatozoa at 0 h, 24 h, 48 h, 72 ...
PALLAVI SINGH, R RANJAN, S D KHARCHE, M K SINGH   +3 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Effect of quantitative feed restriction and realimentation on growth, carcass traits and economics in stallfed Barbari kids

Indian Journal of Animal Sciences, 2019
Four months old 24 Barbari kids were allotted randomly to ad lib. feeding up to 12 months age, 20% (mild) and 40% (moderate) feed restriction at 5th and 6th months (MMFR) and 20, 40, 60% (severe) feed restriction (MMSFR) each of 20 days duration during ...
N RAMACHANDRAN, D SINGH, S K JINDAL, M K SINGH   +3 more
doaj   +1 more source

Comparative performance of Barbari goats under different rearing system in semi-arid region

Indian Journal of Animal Sciences, 2020
This study was undertaken to compare the performance of Barbari goats under grazing system and stall feeding system. Thirty growing Barbari goats of average body weight 15.20±0.54 kg of about 6 months of age were divided into three equal groups (Gr 1 ...
M K SINGH, RAVINDRA KUMAR, S P SINGH
doaj   +1 more source