Results 71 to 80 of about 317,713 (306)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Effect of quantitative feed restriction and realimentation on growth, carcass traits and economics in stallfed Barbari kids

open access: yesIndian Journal of Animal Sciences, 2019
Four months old 24 Barbari kids were allotted randomly to ad lib. feeding up to 12 months age, 20% (mild) and 40% (moderate) feed restriction at 5th and 6th months (MMFR) and 20, 40, 60% (severe) feed restriction (MMSFR) each of 20 days duration during ...
N RAMACHANDRAN   +3 more
doaj   +1 more source

Comparative performance of Barbari goats under different rearing system in semi-arid region

open access: yesIndian Journal of Animal Sciences, 2020
This study was undertaken to compare the performance of Barbari goats under grazing system and stall feeding system. Thirty growing Barbari goats of average body weight 15.20±0.54 kg of about 6 months of age were divided into three equal groups (Gr 1 ...
M K SINGH, RAVINDRA KUMAR, S P SINGH
doaj   +1 more source

Effects of sainfoin hay on gastrointestinal infection with nematodes in goats [PDF]

open access: yes, 2003
EFFECTS OF SAINFOIN HAY ON GASTROINTESTINAL INFECTION WITH NEMATODES IN ...
H., HOSTE, Ph., DORCHIES, V., PAOLINI
core  

The antibody loci of the domestic goat (Capra hircus) [PDF]

open access: yes, 2018
The domestic goat (Capra hircus) is an important ruminant species both as a source of antibody-based reagents for research and biomedical applications and as an economically important animal for agriculture, particularly for developing nations that ...
Bickhart, Derek M.   +4 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Breeding goats for organic production in Germany [PDF]

open access: yes, 2001
With only 120,000 females (year 2000), goat keeping is a niche activity in animal husbandry in Germany. Most of the goats (about 90%) are kept on part-time farms.
Rahmann, Gerold
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Effects of condensed tannins on established populations and on incoming larvae of Trichostrongylus colubriformis and Teladorsagia circumcincta in goats [PDF]

open access: yes, 2003
The use of tanniferous plants or tannins represents one alternative approach to the control of gastrointestinal parasites in ruminants but most data have been obtained in sheep.
Andrey, FRAYSSINES   +4 more
core  

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