Results 61 to 70 of about 138,929 (305)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Influence of floor type on production performance and worm load in lactating Jakhrana goats

Indian Journal of Animal Sciences, 2019
The aim of this study was to investigate the effect of slatted floor (SLF) over soil floor (SOF) on performance of lactating goats reared under group feeding conditions up to 120 days postpartum. Fortnightly live weight and weekly test day milk yield was
N RAMACHANDRAN, S P SINGH, R POUROUCHOTTAMANE, D K SHARMA, S BHUSAN, B RAI, S K JINDAL   +6 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Persistence of the efficacy of copper oxide wire particles against Haemonchus contortus in grazing South African goats [PDF]

, 2012
A study was conducted to examine the duration of anthelmintic effect of copper oxide wire particles (COWP) in grazing goats, as data for the persistence of efficacy of COWP in this host species is limited.
Medley, G. F., Githiori, J.B., Vatta, A. F., Waller, P. J., Medley, Graham, Waller, P.J., Githiori, J. B., Vatta, A.F., Medley, G.F.   +8 more
core   +1 more source

Role of certain growth factors and hormones in folliculogenesis

Indian Journal of Animal Sciences, 2020
Folliculogenesis is an inextricable process associated with female fertility and infertility cases. This process involves many events at cellular and molecular level in a highly orchestrated fashion which culminates with ovulation.
SURESH DINKAR KHARCHE, DAYANIDHI JENA, CHETNA GANGWAR, AMIT KHATTI, B BALAMURUGAN   +4 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Goats excel at learning and remembering a highly novel cognitive task [PDF]

, 2014
PMCID ...
Baciadonna, L., Baciadonna, Luigi, McElligott, Alan G., Luigi Baciadonna, Haque, S., McElligott, Alan; id_orcid, Baciadonna, L, Haque, Samaah, Haque, S, Elodie F Briefer, Briefer, Elodie F., Briefer,, E. F., Alan G McElligott, Samaah Haque, McElligott, AG, Briefer, EF   +15 more
core   +1 more source

Exogenous catalase improves the goat seminal attributes at refrigeration temperature

Indian Journal of Animal Sciences, 2020
The objective of the present study was to evaluate the potential benefit of catalase (CAT) on sperm functional parameters (motility, viability, membrane integrity and acrosomal integrity) during liquid storage of buck spermatozoa at 0 h, 24 h, 48 h, 72 ...
PALLAVI SINGH, R RANJAN, S D KHARCHE, M K SINGH   +3 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source