Results 11 to 20 of about 2,695 (215)

Role of Goblet Cells in Intestinal Barrier and Mucosal Immunity

open access: yesJournal of Inflammation Research, 2021
Songwei Yang1 1, Min Yu2 2 1Key Laboratory for Biorheological Science and Technology of Ministry of Education (Chongqing University), Chongqing University Cancer Hospital, Chongqing, 400030, People’s Republic of China; 2Department of General Surgery ...
Yang S, Yu M
doaj   +2 more sources

Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells

open access: yesLife Science Alliance, 2022
The histone methyltransferase Mll1 controls intestinal secretory cell fate by promoting Wnt-driven Paneth and restricting Mapk-dependent goblet cell differentiation through regulation of Gata4/6 transcription factors Differentiation and lineage ...
Johanna Grinat   +8 more
doaj   +1 more source

Mucus and the Goblet Cell [PDF]

open access: yesDigestive Diseases, 2013
The discovery of an inner mucus layer normally impervious to bacteria has changed our way of understanding the interaction between commensal bacteria and the host epithelial cells. This inner colon mucus layer is rapidly renewed and converted into the outer mucus layer by host controlled endogenous proteolytic processing.
Malin E V, Johansson, Gunnar C, Hansson
openaire   +2 more sources

Goblet Cell Carcinoids of the Appendix [PDF]

open access: yesThe Scientific World Journal, 2013
Goblet cell carcinoid (GCC) tumors are a rare subgroup of neuroendocrine tumors almost exclusively originating in the appendix. The tumor most often presents in the fifth or sixth decade with a clinical picture of appendicitis or in advanced cases an abdominal mass associated with abdominal pain.
Holt, Nanna; id_orcid 0000-0002-2032-1691   +1 more
openaire   +3 more sources

Povidone iodine treatment is deleterious to human ocular surface conjunctival cells in culture

open access: yesBMJ Open Ophthalmology, 2020
Objective To determine the effect of povidone iodine (PI), an antiseptic commonly used prior to ocular surgery, on viability of mixed populations of conjunctival stratified squamous and goblet cells, purified conjunctival goblet cells and purified ...
Miriam Kolko   +12 more
doaj   +1 more source

Vasoactive intestinal peptide regulates ileal goblet cell production in mice

open access: yesPhysiological Reports, 2020
Innervation of the intestinal mucosa has gained more attention with demonstrations of tuft and enteroendocrine cell innervation. However, the role(s) these fibers play in maintaining the epithelial and mucus barriers are still poorly understood.
Luke A. Schwerdtfeger, Stuart A. Tobet
doaj   +1 more source

Immunomodulatory cross-talk between conjunctival goblet cells and dendritic cells. [PDF]

open access: yesPLoS ONE, 2015
Goblet cells are secretory epithelial cells of mucosal tissues that confer protection from environmental agents or pathogens via expression and secretion of soluble mucins.
Laura Contreras-Ruiz, Sharmila Masli
doaj   +1 more source

Clinical and morphological analysis of dysplasia in Barrett's esophagus and columnar-lined esophagus

open access: yesAlʹmanah Kliničeskoj Mediciny, 2020
Background: Barrett's esophagus (BE) is a precan-cerous disease of the esophagus. The risk of adenocarcinoma in BE patients increases with the extension of segment length and with the presence of dysplasia.
L. M. Mikhaleva   +7 more
doaj   +1 more source

Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis

open access: yeseLife, 2021
Intestinal goblet cells maintain the protective epithelial barrier through mucus secretion and yet sample lumenal substances for immune processing through formation of goblet cell associated antigen passages (GAPs).
Jenny K Gustafsson   +9 more
doaj   +1 more source

Inhibition of microRNA-328 Increases Ocular Mucin Expression and Conjunctival Goblet Cells

open access: yesBiomedicines, 2023
We previously reported anti-miR-328 therapy for dry eye disease (DED). Since decreased mucin secretion is a risk factor for DED, we aimed to explore whether anti-miR-328 affects mucin expression and goblet cells.
Jackson Choo   +6 more
doaj   +1 more source

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