Results 131 to 140 of about 56,745 (258)

A Sex-specific Role for Goblet Cells and Mucus Homeostasis in the Intestine. [PDF]

Cell Mol Gastroenterol Hepatol
Gustafsson JK, Knoop KA.
europepmc   +1 more source

Staphylococcus aureus activates NRLP3-dependent IL-1β secretion from human conjunctival goblet cells using α toxin and toll-like receptors 2 and 1. [PDF]

Front Cell Infect Microbiol, 2023
Li D, Hodges R, AukrustNaqvi M, Bair J, Bispo PJM, Gilmore MS, Gregory-Ksander M, Dartt DA.   +7 more
europepmc   +1 more source

Structure of the Secretory Compartments in Goblet Cells in the Colon and Small Intestine. [PDF]

Cells
Mironov AA, Sesorova IS, Vavilov PS, Longoni R, Briata P, Gherzi R, Beznoussenko GV.   +6 more
europepmc   +1 more source

Is Asthma Remission a New Achievable Goal? A Review of the Current Drug‐Related Evidence and Predictors

Allergy, EarlyView.
ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin, Giulia Marcassa, Bianca Olivieri, Gianenrico Senna, Marco Caminati   +4 more
wiley   +1 more source

Goblet Cells and Mucus Composition in Jejunum and Ileum Containing Peyer's Patches and in Colon: A Study in Pigs. [PDF]

Animals (Basel)
Ginoski V, Cortés Sánchez JL, Kahlert S, Schulze Holthausen J, Grześkowiak Ł, Zentek J, Rothkötter HJ.   +6 more
europepmc   +1 more source

The Milk Active Ingredient, 2'-Fucosyllactose, Inhibits Inflammation and Promotes MUC2 Secretion in LS174T Goblet Cells In Vitro. [PDF]

Foods, 2023
Yao Q, Li H, Gao Y, Zheng N, Delcenserie V, Wang J.   +5 more
europepmc   +1 more source

Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma

Allergy, EarlyView.
EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler, Sally E. Wenzel, Steve D. Groshong, Mario Castro, Ian D. Pavord, Klaus F. Rabe, Elizabeth Laws, Alexandre Jagerschmidt, Kaitlyn Gayvert, Sivan Harel, Jennifer D. Hamilton, Nikhil Amin, Lu Zhang, Heming Xing, Anissa Elfakir, Bema Coulibaly, Souâd Naimi, Sara Hamon, Paul J. Rowe, Frank Nestle, Danen M. Cunoosamy, Emanuele de Rinaldis, Leda P. Mannent   +22 more
wiley   +1 more source

Clusterin reverses epitheliopathy, reduces inflammation, and restores goblet cells and corneal nerves in a mouse model of autoimmune dry eye. [PDF]

Sci Rep
Franz J, Ng TF, Gupta S, Wilson MR, Wilson MR, Fini ME, Masli S.   +6 more
europepmc   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Microbiota shape the colon epithelium controlling inter-crypt absorptive goblet cells via butyrate-GP R109A signalling. [PDF]

Gut Microbes
Dias Nirello V, Araújo N, Carvalho de Assis H, Moreno-Gonzalez M, Ruiz P, Castro PR, Shealy NG, Shelton C, Font Fernandes M, de Oliveira S, Boroni M, Ryffel B, Byndloss MX, Beraza N, Ramirez Vinolo MA, Varga-Weisz P.   +15 more
europepmc   +1 more source