Results 161 to 170 of about 4,484,465 (292)
Alterations in Nasal Function Following Total Laryngectomy and Their Clinical Correlates
ABSTRACT Introduction Although nasal structural and functional changes after total laryngectomy (TL) have been documented, the influence of clinical variables and symptoms remains underexplored. This study compared nasal structure and function between TL patients and healthy controls and identified clinical factors associated with these changes ...
Kajornpan Sermwittayawong +3 more
wiley +1 more source
From mucus secretion to immune surveillance: the evolving roles of goblet cells in intestinal homeostasis and inflammation. [PDF]
Du N, Zhang K, Guo J, Yan W, Xu L.
europepmc +1 more source
ABSTRACT Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by inflammatory heterogeneity, epithelial hyperplasia, and tissue remodeling, with spatial pathology critical for deciphering pathological mechanisms and guiding clinical practice.
Zi‐Xuan Hua +12 more
wiley +1 more source
A Nutrient-Dense Diet with Optimal Protein Level Restores Goblet Cells and Alleviates Microbial Dysbiosis in a Mouse Model of Colitis. [PDF]
Jiang L +5 more
europepmc +1 more source
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley +1 more source
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu +3 more
wiley +1 more source
Goblet cells dictate viral tropism and pathogenesis in nasal and intestinal mucosae. [PDF]
Wang W +10 more
europepmc +1 more source
Negative feedback by IRE1β optimizes mucin production in goblet cells [PDF]
In mammals, the prototypical endoplasmic reticulum (ER) stress sensor inositol-requiring enzyme 1 (IRE1) has diverged into two paralogs. IRE1α is broadly expressed and mediates the unconventional splicing of X-box binding protein 1 (XBP1) mRNA during ER ...
Ron, David +19 more
core
Dupilumab in Paediatric Netherton Syndrome: Two Case Reports and a Review of the Literature
ABSTRACT Netherton Syndrome (NS) is a rare genodermatosis characterised by a triad of ichthyosiform erythroderma, an atopic diathesis, and trichorrhexis invaginata, for which no effective management is currently approved in Australia. Dupilumab has demonstrated considerable effectiveness in the treatment of atopic conditions in the paediatric ...
Jacqueline Tu +5 more
wiley +1 more source

