Results 21 to 30 of about 4,075,359 (296)
ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions [PDF]
Experimental and Molecular Medicine, 2023 Inflammatory bowel disease: A protective enzyme in intestinal goblet cells Studies of inflammatory bowel disease (IBD) in mice reveal the role of an enzyme that assists the degradation of mis-folded proteins in the ‘goblet’ cells involved in producing ...
Hyunjin Jeong +13 more
doaj +2 more sources
Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells
Life Science Alliance, 2022 The histone methyltransferase Mll1 controls intestinal secretory cell fate by promoting Wnt-driven Paneth and restricting Mapk-dependent goblet cell differentiation through regulation of Gata4/6 transcription factors Differentiation and lineage ...
Johanna Grinat +8 more
doaj +1 more source
Mucus and the Goblet Cell [PDF]
Digestive Diseases, 2013 The discovery of an inner mucus layer normally impervious to bacteria has changed our way of understanding the interaction between commensal bacteria and the host epithelial cells. This inner colon mucus layer is rapidly renewed and converted into the outer mucus layer by host controlled endogenous proteolytic processing.
Malin E V, Johansson, Gunnar C, Hansson
openaire +2 more sources
Goblet Cell Carcinoids of the Appendix [PDF]
The Scientific World Journal, 2013 Goblet cell carcinoid (GCC) tumors are a rare subgroup of neuroendocrine tumors almost exclusively originating in the appendix. The tumor most often presents in the fifth or sixth decade with a clinical picture of appendicitis or in advanced cases an abdominal mass associated with abdominal pain.
Holt, Nanna; id_orcid 0000-0002-2032-1691 +1 more
openaire +3 more sources
Povidone iodine treatment is deleterious to human ocular surface conjunctival cells in culture
BMJ Open Ophthalmology, 2020 Objective To determine the effect of povidone iodine (PI), an antiseptic commonly used prior to ocular surgery, on viability of mixed populations of conjunctival stratified squamous and goblet cells, purified conjunctival goblet cells and purified ...
Miriam Kolko +12 more
doaj +1 more source
Vasoactive intestinal peptide regulates ileal goblet cell production in mice
Physiological Reports, 2020 Innervation of the intestinal mucosa has gained more attention with demonstrations of tuft and enteroendocrine cell innervation. However, the role(s) these fibers play in maintaining the epithelial and mucus barriers are still poorly understood.
Luke A. Schwerdtfeger, Stuart A. Tobet
doaj +1 more source
Clinical and morphological analysis of dysplasia in Barrett's esophagus and columnar-lined esophagus
Alʹmanah Kliničeskoj Mediciny, 2020 Background: Barrett's esophagus (BE) is a precan-cerous disease of the esophagus. The risk of adenocarcinoma in BE patients increases with the extension of segment length and with the presence of dysplasia.
L. M. Mikhaleva +7 more
doaj +1 more source
eLife, 2021 Intestinal goblet cells maintain the protective epithelial barrier through mucus secretion and yet sample lumenal substances for immune processing through formation of goblet cell associated antigen passages (GAPs).
Jenny K Gustafsson +9 more
doaj +1 more source
Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells. [PDF]
PLoS ONE, 2009 The bronchioles of the murine lung are lined by a simple columnar epithelium composed of ciliated, Clara, and goblet cells that together mediate barrier function, mucociliary clearance and innate host defense, vital for pulmonary homeostasis.
David H Tompkins +7 more
doaj +1 more source
Goblet Cell Carcinoma of the Appendix: A Case Report on Goblet Cell Carcinoid
HCA Healthcare Journal of Medicine, 2020 Goblet cell carcinoid of the appendix is a rare neoplasm with histological features of both neuroendocrine and adenocarcinomas. The combination of its aggressive behavior, infrequent occurrence, and variable clinical presentation convolutes the management of this tumor. We report the case of a 75-year-old female presenting with acute appendicitis.
Sheliza, Kabani +3 more
openaire +3 more sources