Results 131 to 140 of about 4,075,359 (296)

Expression of MUC5AC mRNA in the Goblet Cells of Human Nasal Mucosa [PDF]

, 2001
Background and Objectives：Mucus hypersecretion is a common feature in chronic sinusitis with polyps. Since mucus hypersecretion is commonly accompanied by goblet cell hyperplasia, it is important to identify which mucin gene mRNAs are expressed in the ...
윤주헌, 김창훈
core  

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Effects of Lactic Acid Bacteria and Yeasts on Growth Performance, Intestinal Health, and Organ Morphometry of Broiler Chickens

Food Safety and Health, EarlyView.
The fermentation of molasses‐vinasse with lactic acid bacteria and yeasts improves growth, intestinal health, digestive, and immune organs in chickens, promoting their productive performance and organic development. ABSTRACT This study evaluated the probiotic effects of lactic acid bacteria and yeasts on productive parameters, intestinal health, and ...
José Miranda‐Yuquilema, Fabian Astudillo‐Riera, Juan Taboada‐Pico, Mercy Cuenca‐Condo, Kevin Astudillo‐Vallejo   +4 more
wiley   +1 more source

Immunomodulatory function of conjunctival goblet cells in ocular surface mucosa.

, 2015
In response to an LPS-mediated stimulus, conjunctival goblet cells increase expression of TGF-ß2, and activate it in a TSP-1 dependent manner via a TSP-1 receptor, CD36.
Laura Contreras-Ruiz (461999), Sharmila Masli (87768)   +1 more
core   +1 more source

Advances in Immunological Combination Therapy for Colorectal Cancer

iMetaMed, EarlyView.
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu, Rongbo Wen, Tianshuai Zhang, Fuao Cao, Xiaoming Zhu, Liqiang Hao, Wei Zhang, Guanyu Yu   +7 more
wiley   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Discours prononcé par M. Goblet, ministre de l'Instruction publique et des Beaux-Arts, à l’inauguration de l’école nationale d'enseignement professionnel de Voiron (Isère). Le 3 Octobre 1886

, 1886
Goblet René. Discours prononcé par M. Goblet, ministre de l'Instruction publique et des Beaux-Arts, à l’inauguration de l’école nationale d'enseignement professionnel de Voiron (Isère). Le 3 Octobre 1886.
Goblet, René
core  

Table_1_Mucosal affairs: glycosylation and expression changes of gill goblet cells and mucins in a fish–polyopisthocotylidan interaction.XLSX [Dataset]

[Introduction]: Secreted mucins are highly O-glycosylated glycoproteins produced by goblet cells in mucosal epithelia. They constitute the protective viscous gel layer overlying the epithelia and are involved in pathogen recognition, adhesion and ...
Oswaldo Palenzuela (4721736), Enrique Riera-Ferrer (13449708), Muñoz-Berruezo, Uxue, Raquel Del Pozo (13770765), Estensoro, Itziar, M. Carla Piazzon (5576864), Riera-Ferrer, E., Palenzuela, Oswaldo, Sitjà-Bobadilla, Ariadna, Piazzon de Haro, María Carla, Ariadna Sitjà-Bobadilla (421074), Pozo, R. del, Itziar Estensoro (421070), Uxue Muñoz-Berruezo (18330699)   +13 more
core   +1 more source

Goblet Cells are Derived from a FOXJ1-Expressing Progenitor in a Human Airway Epithelium

, 2011
The overproduction of mucus is a key pathology associated with respiratory diseases, such as asthma and chronic obstructive pulmonary disease. These conditions are characterized by an increase in the number of mucus-producing goblet cells in the airways.
Combe, Delphine, Jones, Carol, Gino Van Heeke, June Giddings, Van Heeke, Gino, Roger, Jan, Turner, Jonathan, Fitau, Juliette, Giddings, June, Jonathan Turner, Juliette Fitau, Jan Roger, Delphine Combe, Carol E. Jones   +13 more
core   +1 more source

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source