Results 151 to 160 of about 91,974 (203)
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The International Journal of Biochemistry & Cell Biology, 2003
The two principal features of airway goblet cells are rapid secretion of mucin onto the airway surface and increase in number (hyperplasia) with chronic inhaled 'insult'. The first is associated with homeostasis, the latter with pathophysiology. Myristoylated alanine-rich C kinase (MARCKS) is a key molecule regulating mucin exocytosis, a process also ...
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The two principal features of airway goblet cells are rapid secretion of mucin onto the airway surface and increase in number (hyperplasia) with chronic inhaled 'insult'. The first is associated with homeostasis, the latter with pathophysiology. Myristoylated alanine-rich C kinase (MARCKS) is a key molecule regulating mucin exocytosis, a process also ...
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Seminars in Diagnostic Pathology
Appendix, considered a vestigial and disposable organ, has been long neglected as a source of abdominal tumors. Among the appendiceal tumors, goblet cell adenocarcinoma (GCA) is a rare primary epithelial neoplasm which has undergone multiple name changes and classifications in recent years, adding to confusion surrounding this unique amphicrine tumor ...
Jula, Veerapong, Mojgan, Hosseini
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Appendix, considered a vestigial and disposable organ, has been long neglected as a source of abdominal tumors. Among the appendiceal tumors, goblet cell adenocarcinoma (GCA) is a rare primary epithelial neoplasm which has undergone multiple name changes and classifications in recent years, adding to confusion surrounding this unique amphicrine tumor ...
Jula, Veerapong, Mojgan, Hosseini
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Goblet cell carcinoid of the appendix
Cancer, 1974Twelve tumors of the appendix are described which show histologic features different from both ordinary carcinoid and adenocarcinoma. The principal cell type has a close resemblance to the normal goblet cell in the epithelium of the intestinal tract. Paneth's and argentaffin cells were present in considerable numbers in some of these tumors.
S G, Subbuswamy +3 more
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Goblet cell carcinoid of the appendix
Human Pathology, 1982A goblet cell carcinoid (adenocarcinoid) of the appendix was studied ultrastructurally and found to have features at variance with those of previously reported cases. The findings support a hypothesis that adenocarcinoids represent a composite, biphasic neoplasm of two morphologically differentiated cells, each derived from a common endodermal ...
F H, Rodriguez, D P, Sarma, J H, Lunseth
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Science Signaling, 2023
Autophagy augments the mucus-secreting capacity of goblet cells by reducing ER stress.
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Autophagy augments the mucus-secreting capacity of goblet cells by reducing ER stress.
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Mucins, Mucus, and Goblet Cells
Chest, 2018The respiratory epithelium is lined by mucus, a gel consisting of water, ions, proteins, and macromolecules. The major macromolecular components of mucus are the mucin glycoproteins, which are critical for local defense of the airway. There are three classes of mucins in the airways: those that are secreted but do not polymerize (MUC7), those that are ...
Jonathan, Ma +2 more
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Goblet Cells Secretion and Mucogenesis
Annual Review of Physiology, 1990In the final discussions of the last Ciba Symposium on Mucus and Mucosa (London, 1984), I voiced my impression that, in this gelatinous drama of mucus formation, several scripts were looking for characters, and some characters were looking for roles. Now, four years later, we have been able to locate a few of the missing characters and see them play ...
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Management of goblet cell carcinoid
Journal of Surgical Oncology, 2006AbstractBackground and ObjectivesGoblet cell carcinoid, a rare tumor of intermediate malignant potential, is known to account for a significant minority of appendiceal neoplasms. Sixteen new cases of gastrointestinal goblet cell carcinoid were reviewed to describe their presentation, treatment, and outcome.MethodsA review of 16 cases from a single ...
John C, Byrn +4 more
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Science, 2021
Gut Physiology An adult human has a gut surface area averaging 30 square meters that is bombarded daily by xenobiotics and microorganisms. Mucus synthesized by goblet cells supplies a protective barrier coating. Nystrom et al. discovered that goblet cells are not all the same along the length of the gut; rather, they form different functional ...
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Gut Physiology An adult human has a gut surface area averaging 30 square meters that is bombarded daily by xenobiotics and microorganisms. Mucus synthesized by goblet cells supplies a protective barrier coating. Nystrom et al. discovered that goblet cells are not all the same along the length of the gut; rather, they form different functional ...
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