Results 41 to 50 of about 4,075,359 (296)

Early transcriptional response in the jejunum of germ-free piglets after oral infection with virulent rotavirus [PDF]

, 2008
Germ-free piglets were orally infected with virulent rotavirus to collect jejunal mucosal scrapings at 12 and 18 hours post infection (two piglets per time point).
Hulst, M.M., Wit, A.A.C., de, van der Meulen, J., Niewold, T., Meulen, J., van der, de Wit, A.A.C., Smits, M.A., Kerstens, H.H.D.   +7 more
core   +1 more source

Novel insights into the study of goblet cell hypersecretion in allergic rhinitis

Frontiers in Immunology
Goblet cell hypersecretion is a hallmark of airway inflammation and is driven by complex neuroimmune regulation involving submucosal glands and goblet cells. Although studies have focused on mast cell degranulation as a critical driver of nasal secretion,
Xiaojia Zhu, Xiaojia Zhu, Fengli Cheng, Hongying Duan, Hongying Duan, Sirui Fu, Sirui Fu, Changqing Zhao   +7 more
doaj   +1 more source

Modulation of Conjunctival Goblet Cell Function by Inflammatory Cytokines

Mediators of Inflammation, 2013
Ocular surface inflammation associated with Sjögren’s syndrome is characterized by a loss of secretory function and alteration in numbers of mucin secreting goblet cells.
L. Contreras-Ruiz, A. Ghosh-Mitra, M. A. Shatos, D. A. Dartt, S. Masli   +4 more
doaj   +1 more source

Toll-like receptor 4 damages the intestinal epithelial cells by activating endoplasmic reticulum stress in septic rats [PDF]

PeerJ
Background The severity of acute gastrointestinal injury (AGI) is a critical determinant of survival in sepsis. However, there is no specifically interventional management for gastrointestinal dysfunction.
Xue Wu, Jilin Yang, Xin Bao, Yijie Wang
doaj   +2 more sources

Influence of in ovo inoculation of probiotic strains on the jejunal goblet cell counts and morphometry in peri- and post-hatching chicks [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017
The objective of the present study was to evaluate the effects of in ovo inoculation of different probiotic strains (Bacillus subtilis, Enterococcus faecium, and Pediococcus acidilactici) on jejunal goblet cells counts and morphometry in chicken ...
MAJIDI-MOSLEH A, SADEGHI AA, MOUSAVI SN, CHAMANI M, ZAREI A   +4 more
doaj   +1 more source

Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2

The EMBO Journal, 2023
Intestinal goblet cells are secretory cells specialized in the production of mucins, and as such are challenged by the need for efficient protein folding.
Eva Cloots, Phaedra Guilbert, Mathias Provost, Lisa Neidhardt, Evelien Van de Velde, Farzaneh Fayazpour, Delphine De Sutter, Savvas N Savvides, Sven Eyckerman, Sophie Janssens   +9 more
doaj   +1 more source

Absence of gut microbiota impairs depletion of Paneth cells but not goblet cells in germ-free Atoh1lox/lox VilCreERT2 mice. [PDF]

, 2023
Mouse atonal homolog 1 (Math1/Atoh1) is a basic helix-loop-helix transcription factor important for the differentiation of secretory cells within the intestinal epithelium.
Kellmann, Philipp, Gomez de Agüero, Mercedes, Stephanie C. Ganal-Vonarburg, Mercedes Gomez de Agüero, Jakob Zimmermann, Mohsin Hassan, Philipp Kellmann, Stefania Huber, Edoardo Lazzarini, Huber, Stefania, Lazzarini, Edoardo, Hassan, Mohsin, Juanola, Oriol, Moghadamrad, Sheida, Zimmermann, Jakob, Oriol Juanola, Ganal-Vonarburg, Stephanie C, Sheida Moghadamrad   +17 more
core   +2 more sources

Goblet Cell Carcinoid of the Appendix.

Internal Medicine, 1994
A 47-year-old man was admitted with appendicitis, and appendectomy was performed. On microscopic examination of the resected specimen, the presence of goblet cell carcinoid in the tip of appendix was revealed. This tumor showed an aggressive nature with perineural and vascular invasion around the appendiceal serosa.
ZEA-IRIARTE, Walter Leopoldo, ITO, Masahiro, NAITO, Shinji, NAKAYAMA, Toshiyuki, ITSUNO, Minoru, FUJII, Hideharu, FURUKAWA, Masato, MAKIYAMA, Kazuya, SEKINE, Ichiro   +8 more
openaire   +5 more sources

Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells. [PDF]

PLoS ONE, 2013
Intestinal epithelial cells (IECs) regulate the absorption and secretion of anions, such as HCO3(-) or Cl(-). Bestrophin genes represent a newly identified group of calcium-activated Cl(-) channels (CaCCs).
Go Ito, Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Tomohiro Mizutani, Shiro Yui, Junko Akiyama-Morio, Yasuhiro Nemoto, Eriko Okada, Akihiro Araki, Kazuo Ohtsuka, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe   +15 more
doaj   +1 more source

Keeping goblet cells unstressed: new insights into a general principle. [PDF]

EMBO J
The regulation of unfolded protein response (UPR) sensors has been studied for over 20 years, but IRE1β has remained a mystery. IRE1β is highly expressed in goblet cells: specialized epithelial cells that secrete mucus.
Bertolotti A.
europepmc   +4 more sources