Understanding exosomes in regenerative dentistry
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source
Sex-dependent differential increase of specialized pro-resolving mediators in extracellular vesicles secreted by human primary conjunctival goblet cells during allergic inflammation. [PDF]
Lee C, Dartt DA.
europepmc +1 more source
Periodontitis and metabolic dysfunction‐associated steatotic liver disease
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon +6 more
wiley +1 more source
Induction of intercrypt goblet cells upon bacterial infection: a promising therapeutic target to restore the mucosal barrier. [PDF]
Léonard R +10 more
europepmc +1 more source
Modified Gegen Qinlian Decoction modulated the gut microbiome and bile acid metabolism and restored the function of goblet cells in a mouse model of ulcerative colitis. [PDF]
Huang J, Zhang J, Wang F, Tang X.
europepmc +1 more source
Fine‐Needle Aspirate Cytology of Feline Pulmonary Langerhans Cell Histiocytosis in Two Cats
ABSTRACT Feline pulmonary Langerhans cell histiocytosis (FPLCH) is a rare histiocytic disorder in cats, usually diagnosed post‐mortem following natural death or euthanasia for severe respiratory distress. Antemortem diagnosis has been reported only once, achieved by cytologic examination of bronchoalveolar lavage fluid combined with immunocytochemistry,
Karuna Katariwala +7 more
wiley +1 more source
Tear Film Dynamics in Visual Display Terminal Users: A Review of Impact on Goblet Cells, Lacrimal and Meibomian Gland Function. [PDF]
Maity M, Galor A, Basu S, Singh S.
europepmc +1 more source
Abstract Exercise in hot climates increases the risk of gastrointestinal (GI) disruption and respiratory illness. We investigated the effects of a 42 day prebiotic intervention on markers of intestinal epithelial injury, GI discomfort and immunity following football specific exercise in the heat and daily upper respiratory illness.
Connor J. Parker +6 more
wiley +1 more source
Translating gut microbiome research into therapies for type 1 diabetes
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok +2 more
wiley +1 more source
Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto +3 more
wiley +1 more source

