Results 141 to 150 of about 56,726 (258)

A Sex-specific Role for Goblet Cells and Mucus Homeostasis in the Intestine. [PDF]

Cell Mol Gastroenterol Hepatol
Gustafsson JK, Knoop KA.
europepmc   +1 more source

Staphylococcus aureus activates NRLP3-dependent IL-1β secretion from human conjunctival goblet cells using α toxin and toll-like receptors 2 and 1. [PDF]

Front Cell Infect Microbiol, 2023
Li D, Hodges R, AukrustNaqvi M, Bair J, Bispo PJM, Gilmore MS, Gregory-Ksander M, Dartt DA.   +7 more
europepmc   +1 more source

Small Airways Dysfunction and Remission in Adults With Asthma: A Longitudinal Exploratory Analysis of the AssessmenT of smalL Airways involvemeNT In aSthma (ATLANTIS) Study

Allergy, EarlyView.
We conducted a post hoc analysis of ATLANTIS, a multinational prospective study including 684 adults with asthma. Fewer small airway symptoms and lower disease activity are independently associated with asthma remission. Replicated airway transcriptomic signatures show increased IL‐4/13 signalling and reduced coagulation pathways across the ATLANTIS ...
Akshi Kumar, Rory Chan, Nazanin Zounemat‐Kermani, Eleanor Quek, Ian M. Adcock, Bianca Beghe, Christopher Brightling, Dave Singh, Janwillem Kocks, Alberto Papi, Klaus F. Rabe, Ulrica Scaffidi‐Argentina, Maarten van den Berge, Monica Kraft, Salman Siddiqui   +14 more
wiley   +1 more source

Structure of the Secretory Compartments in Goblet Cells in the Colon and Small Intestine. [PDF]

Cells
Mironov AA, Sesorova IS, Vavilov PS, Longoni R, Briata P, Gherzi R, Beznoussenko GV.   +6 more
europepmc   +1 more source

The Milk Active Ingredient, 2'-Fucosyllactose, Inhibits Inflammation and Promotes MUC2 Secretion in LS174T Goblet Cells In Vitro. [PDF]

Foods, 2023
Yao Q, Li H, Gao Y, Zheng N, Delcenserie V, Wang J.   +5 more
europepmc   +1 more source

Nasal Airway Transcriptome Reflects Selected Asthma‐Associated Gene Signatures in the Lower Airways

Allergy, EarlyView.
Seven genes and two gene modules were consistently associated with asthma in both airway compartments in ARMS and were validated in ATLANTIS. The two modules reflected IL‐13 related inflammation and mast cell activity, respectively. Nasal gene signatures provide a non‐invasive proxy for selected bronchial asthma‐associated gene signatures. ARMS, Asthma
Hui Wen, Tessa Kole, Orestes A. Carpaij, Tatiana Karp, Victor Guryev, Alen Faiz, Kian Fan Chung, Pankaj Bhavsar, Ian M. Adcock, Salman Siddiqui, Andy Lan, Katie L. Raby, Nazanin Zounemat‐Kermani, Chris Brightling, Dave Singh, Janwillem Kocks, Monica Kraft, Bianca Beghé, Klaus F. Rabe, Alberto Papi, Machteld N. Hylkema, Martijn C. Nawijn, Maarten van den Berge   +22 more
wiley   +1 more source

Goblet Cells and Mucus Composition in Jejunum and Ileum Containing Peyer's Patches and in Colon: A Study in Pigs. [PDF]

Animals (Basel)
Ginoski V, Cortés Sánchez JL, Kahlert S, Schulze Holthausen J, Grześkowiak Ł, Zentek J, Rothkötter HJ.   +6 more
europepmc   +1 more source

Clusterin reverses epitheliopathy, reduces inflammation, and restores goblet cells and corneal nerves in a mouse model of autoimmune dry eye. [PDF]

Sci Rep
Franz J, Ng TF, Gupta S, Wilson MR, Wilson MR, Fini ME, Masli S.   +6 more
europepmc   +1 more source

Goblet cells as mucosal sentinels for immunity [PDF]

Mucosal Immunology, 2017
McGuckin, M. A., Hasnain, S. Z.
openaire   +5 more sources

Is Asthma Remission a New Achievable Goal? A Review of the Current Drug‐Related Evidence and Predictors

Allergy, EarlyView.
ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin, Giulia Marcassa, Bianca Olivieri, Gianenrico Senna, Marco Caminati   +4 more
wiley   +1 more source