Results 191 to 200 of about 195,075 (267)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Understanding Public Perspectives on Direct to Consumer Pharmacogenomic Testing in the UK: A Qualitative Study

Mathieson A, Brunton L, Gillibrand S, Moldovan R, McDermott J.   +4 more
europepmc   +1 more source

Elucidating the phase 1 trial experience among study participants following completion of the INTERCEPT-AD study of sabirnetug (ACU193) for early Alzheimer's disease: a qualitative interview study. [PDF]

Trials
Merikle E, Presnall C, Feaster T, Moxon R, Siemers E, Kerwin D, Cline S.   +6 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Insights From Black Living Kidney Donors: An Interview Study on APOL1 Genetic Testing Experiences. [PDF]

Clin Transplant
Iltis AS, Walsh HA, Baldwin K, McIntosh T, Mohan S, Sawinski D, Goodman MS, DuBois JM.   +7 more
europepmc   +1 more source

Intensive longitudinal follow-up of cisgender and transgender women engaged in sex work during the three months following initiation of daily oral PrEP: A series of case-studies with mixed-method assessments. [PDF]

PLOS Glob Public Health
Vazquez Guillamet LJ, Valencia J, Ryan P, Matarranz M, Cuevas-Tascón G, Del-Olmo-Morales MA, Laguna L, Casanueva N, Viladomiu C, Matthews LT, Lazarus JV, Chevance G.   +11 more
europepmc   +1 more source

The freebirth debate: Respecting autonomy while reflecting on our own practices. [PDF]

Acta Obstet Gynecol Scand
Gunnarsdóttir J, Hjartardóttir H.
europepmc   +1 more source

Patients' Concerns for Hormone-Replacement Therapy for Menopause. [PDF]

Cureus
Distler KR, Kappers D, Hollingsworth JC.
europepmc   +1 more source

Controlling Symptoms versus Minimizing Negative Treatment Impact: A Grounded Theory Study of Heterogeneity in Patient Preferences for Psoriasis Treatments. [PDF]

Patient Prefer Adherence
Szabo SM, Hawkins NS, Germeni E.
europepmc   +1 more source

Primary Care Practitioners' Approaches to Deprescribing Opioids for Older Adults With Chronic Pain: A Qualitative Analysis. [PDF]

J Am Geriatr Soc
Wang BX, Lindenberg JH, Herzig SJ, Schonberg MA, Anderson TS.   +4 more
europepmc   +1 more source