Results 31 to 40 of about 1,099,253 (266)

The Kumtor gold deposit in the Middle Tien Shan, Kyrgyzstan, and the application of 3-D modeling in Seequent’s Leapfrog Geo software for the geological exploration

open access: yesРуды и металлы, 2023
The Kumtor deposit is one of the largest gold deposits in the Tien Shan. The ore zones are localized in rocks of the black shale formation, in an amagmatic gently dipping structure.
Shevkunov A. G.   +3 more
doaj   +1 more source

Gold for Gold

open access: yesSeptentrio Conference Series, 2014
(Abstract missing)
openaire   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

An unusual case of invasive pleuritis and miliary Mycoplasma pneumonia during check‐point inhibitor therapy

open access: yesRespirology Case Reports, 2021
A growing body of evidence suggests that check‐point inhibitors not only increase the overall risk of infections, but, due to an altered immune response, may also result in atypical manifestations.
Daniel Bird, Maninder Singh
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Mineralogy Characteristics of Overflow Product from Hydrocyclone in the Jiaojia Gold Mine

open access: yesYankuang ceshi, 2014
The capacity of ore treatment reached 12,000 t/d and gold recovery achieved 92% in the Jiaojia Gold Mine. Broken product has been washed with double spiral classifier, and the ore slime yield was 7%.
HU Hai-xiang   +5 more
doaj   +2 more sources

The impact of improved surgical safety checklist participation on OR efficiencies: A pretest-post test analysis

open access: yesJournal of Perioperative Nursing, 2019
Objective: To describe changes in day of surgery (DOS) cancellations and procedural delays following introduction of a practice improvement intervention to improve team members’ participation in the surgical safety checklist (SSC).
Brigid Gillespie   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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